Browsing Research Articles (Internal Medicine) by Title

Browsing Research Articles (Internal Medicine) by Title

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  • Comparison of the diagnostic potential of three anti-citrullinated protein antibodies as adjuncts to rheumatoid factor and CCP in a cohort of South African rheumatoid arthritis patients 
    Meyer, Pieter Willem Adriaan; Ally, Mahmood Moosa Tar Mahomed; Hodkinson, Bridget; Anderson, Ronald; Tikly, Mohammed (Springer, 2018-06)
    PURPOSE : A retrospective comparison of the prevalence and diagnostic value of anti-Sa, anti-CEP-1, and anti-MCV autoantibodies relative to those of the established autoantibodies, composite RF and anti-CCP-IgG used routinely ...
  • Comparison of the effects of electronic cigarette vapours and tobacco smoke extracts on human neutrophils in vitro 
    Richards, G.A.; Theron, Annette J.; Van den Bout, Jan Iman; Anderson, Ronald; Feldman, Charles; Van Zyl Smit, Richard; Chang, Ju-Wei; Tintinger, Gregory (European Respiratory Society, 2023-05)
    BACKGROUND : Electronic cigarettes (ECs) are electronic aerosol delivery systems composed of nicotine and various chemicals, which are widely used to facilitate smoking cessation. Although ECs are considered safer than ...
  • A comparison of the pharmacokinetics of Aspen Ceftriaxone and Rocephin in community-acquired meningitis 
    Richards, Guy A.; Elliott, E.; Shaddock, E.J.; Mushi, D.; Mzileni, M.; Ray, R.; Rulisa, S.; Seolwane, F.; Stacey, S.L.; Stoltz, Anton Carel; Venturas, J.P.; Schoeman, H. (Health and Medical Publishing Group, 2013-12)
    BACKGROUND. Community-acquired bacterial meningitis (CABM) is a life-threatening condition that is common among immunocompromised individuals. Intravenous ceftriaxone, of which Rocephin (ROC) is the originator brand, is ...
  • Coronavirus and pregnancy : the challenges of the 21(st) Century : a review 
    Adam, Sumaiya; Pheiffer, Carmen; Dias, Stephanie; Hlongwane, T.M.A.G. (Tsakane); Vannevel, Valerie; Soma-Pillay, Priya; Abdullah, Fareed (Frontiers Media SA, 2022-07-13)
    Despite many advances in medicine we are still faced with emerging pathogens. Pregnant women have been disproportionately affected by previous coronavirus outbreaks. The COVID-19 pandemic has not affected pregnant women ...
  • The correlation between C-reactive protein and toxic granulation of neutrophils in the peripheral blood 
    Van de Vyver, Annemarie; Delport, Eluned F.; Esterhuizen, M.; Pool, Roger (Health and Medical Publishing Group, 2010-07)
    BACKGROUND: During inflammation, the serum concentrations of granulocyte colony-stimulating factor (G-CSF), plasma interleukin-6 (IL-6), and C-reactive protein (CRP) increase. A positive correlation between CRP and the ...
  • Could genetics be the answer? 
    Ker, James A. (New Media Publishing, 2017-10)
    Atherosclerotic coronary artery disease is responsible for millions of deaths worldwide on a yearly basis.
  • COVID-19 severity and in-hospital mortality in an area with high HIV prevalence 
    Boswell, Michael; Maimela, T.C.R. (Tshegofatso); Hameiri-Bowen, Dan; Riley, George; Malan, Albertus; Steyn, Nickietta; Nolutshungu, Nomonde; De Villiers, Talita R.; De Beer, Zelda; Mathabathe, John; Tshabalala, Khanyisile; Abdullah, Fareed; Ramlall, Rajiev; Heystek, Marthinus J.; Basu, Debashis; Rheeder, Paul; Ueckermann, Veronica; Van Hougenhouck-Tulleken, W.G. (Wesley) (AOSIS, 2023-01-27)
    BACKGROUND : HIV infection causes immune dysregulation affecting T-cell and monocyte function, which may alter coronavirus disease 2019 (COVID-19) pathophysiology. OBJECTIVES : We investigated the associations among ...
  • The COVID-19 treatment landscape : a South African perspective on a race against time 
    Hendricks, Candice Laverne; Herd, Candice Lee; Nel, Marcel; Tintinger, Gregory Ronald; Pepper, Michael Sean (Frontiers Media, 2021-02-19)
    The pandemic caused by SARS-CoV-2 has infected more than 94 million people worldwide (as of 17 January 2020). Severe disease is believed to be secondary to the cytokine release syndrome (CRS or “cytokine storm”) which ...
  • A crazy cause of dyspnoea : pulmonary alveolar proteinosis 
    Soma, Prashilla; Ellemdin, Shiraz; Roche, Natalie J. (Elsevier, 2014-08)
    In March, 2013, a 37-year-old woman presented to the emergency department with a 6 month history of worsening dyspnoea, fatigue, insomnia, and generalised body pains. She had no cough or haemoptysis, was a non-smoker, and ...
  • Cross-reactive neutralizing antibody responses elicited by SARS-CoV-2 501Y.V2 (B.1.351) 
    Moyo‑Gwete, Thandeka; Madzivhandila, Mashudu; Makhado, Zanele; Ayres, Frances; Mhlanga, Donald; Oosthuysen, Brent; Lambson, Bronwen E.; Kgagudi, Prudence; Tegally, Houriiyah; Iranzadeh, Arash; Doolabh, Deelan; Tyers, Lynn; Chinhoyi, Lionel R.; Mennen, Mathilda; Skelem, Sango; Marais, Gert; Wibmer, Constantinos K.; Bhiman, Jinal N.; Ueckermann, Veronica; Rossouw, Theresa M.; Boswell, Michael T.; De Oliveira, Tulio (Massachusetts Medical Society, 2021-06)
    No abstract available.
  • Cryptogenic, embolic stroke-looking backstage 
    Ker, James A. (Elsevier, 2022-05)
    Stroke is a common and devastating event and the majority of cases are caused by thromboembolism from the left atrium, left ventricle or left sided valves. This case report describes a case of embolic stroke with the origin ...
  • Cytomegalovirus viral load kinetics in patients with HIV/AIDS admitted to a medical intensive care unit : a case for pre-emptive therapy 
    Mayaphi, Simnikiwe Horatious; Brauer, Marieke; Morobadi, Daniel M.; Mazanderani, Ahmad Haeri; Mafuyeka, Rendani T.; Olorunju, Steve A.S.; Tintinger, Gregory Ronald; Stoltz, Anton Carel (Public Library of Science, 2014-04-03)
    BACKGROUND : Cytomegalovirus (CMV) infection is associated with severe diseases in immunosuppressed patients; however, there is a lack of data for pre-emptive therapy in patients with HIV/AIDS. METHOD : This was a ...
  • Dance as physical exercise for older people 
    Viljoen, Margaretha; Levay, Peter Ferenc (Academy of Science of South Africa, 2021-11)
    The importance of adequate physical activity for older people cannot be overestimated. Evidence exists that physical exercise can improve quality of life; benefit brain areas involved with executive control; delay the ...
  • Decision-making using absolute cardiovascular risk reduction and incremental cost-effectiveness ratios : a case study 
    Ker, James A.; Oosthuizen, H.; Rheeder, Paul (Clinics Cardiv, 2008-03)
    BACKGROUND: Many clinical guidelines have adopted a multifactorial cardiovascular risk assessment to identify high-risk individuals for treatment. The framingham risk chart is a widely used risk engine to calculate the ...
  • Decline in antibody responses to SARS-CoV-2 post-vaccination poses a risk to health care workers 
    Worsley, Catherine M.; Van der Mescht, Mieke Adri; Hoffmann, Daniel; Meyer, Pieter Willem Adriaan; Ueckermann, Veronica; Rossouw, Theresa M. (Elsevier, 2022-09)
    No abstract available.
  • Decreased CD10 expression in the bone marrow neutrophils of HIV positive patients 
    Van de Vyver, Annemarie; Delport, Eluned F.; Visser, Adele (Open Journal System, 2010-11)
    BACKGROUND: HIV-1 infection is associated with various quantitative and qualitative changes in haemopoietic cells. Clear distinction between primary myelodysplastic syndrome (MDS) and secondary dysplasia may not always be ...
  • Decreased severity of disease during the first global Omicron variant COVID-19 outbreak in a large hospital in Tshwane, South Africa 
    Abdullah, Fareed; Myers, J.; Basu, Debashis; Tintinger, Gregory; Ueckermann, Veronica; Mathebula, M.; Ramlall, R.; Spoor, S.; De Villiers, T.; Van der Walt, Z.; Cloete, Jeane; Soma-Pillay, Priya; Rheeder, Paul; Paruk, Fathima; Engelbrecht, Adel; Lalloo, Vidya; Myburg, M.; Kistan, J.; Van Hougenhouck-Tulleken, W.G. (Wesley); Boswell, Michael T.; Gray, G.; Welch, R.; Blumberg, Lucille Hellen; Jassat, W. (Elsevier, 2022-03)
    INTRODUCTION : The coronavirus disease 2019 (COVID-19) first reported in Wuhan, China in December 2019 is a global pandemic that is threatening the health and wellbeing of people worldwide. To date there have been more ...
  • Despite delayed kinetics, people living with HIV achieve equivalent antibody function after SARS-CoV-2 infection or vaccination 
    Motsoeneng, Boitumelo M.; Manamela, Nelia; Kaldine, Haajira; Kgagudi, Prudence; Hermanus, Tandile; Ayres, Frances; Makhado, Zanele; Moyo-Gwete, Thandeka; Van der Mescht, Mieke Adri; Abdullah, Fareed; Boswell, Michael; Ueckermann, Veronica; Rossouw, Theresa; Madhi, Shabir A.; Moore, Penny L.; Richardson, Simone I. (Frontiers Media, 2023-08-03)
    The kinetics of Fc-mediated functions following SARS-CoV-2 infection or vaccination in people living with HIV (PLWH) are not known. We compared SARS-CoV-2 spike-specific Fc functions, binding, and neutralization in ...
  • Detection of acute and early HIV-1 infections in an HIV hyper-endemic area with limited resources 
    Mayaphi, Simnikiwe Horatious; Martin, Desmond J.; Quinn, Thomas C.; Laeyendecker, Oliver; Olorunju, Steve A.S.; Tintinger, Gregory Ronald; Stoltz, Anton Carel (Public Library of Science, 2016-10-20)
    BACKGROUND: Two thirds of the world's new HIV infections are in sub-Saharan Africa. Acute HIV infection (AHI) is the time of virus acquisition until the appearance of HIV antibodies. Early HIV infection, which includes ...
  • Detection of neutralizing antibodies in COVID-19 patients from Steve Biko Academic Hospital Complex : a pilot study 
    Kgatle, Mankgopo; Chalwe, Joseph Musonda; Van der Westhuizen, Donald; Xu, Shuting; Damane, Botle Precious; Mathebela, Precious; Ueckermann, Veronica; Mayaphi, Simnikiwe; Rodrigues, Hosana Gomes; Moura-Alves, Pedro; Ndlovu, Honest; Mzizi, Yonwaba; Zongo, Lusanda; Hairwadzi, Henry; Vorster, Mariza; Zeevaart, Jan Rijn; Sathekge, Mike Machaba (MDPI, 2023-07-03)
    A correlation between neutralization activity after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination and protection against coronavirus disease 2019 (COVID-19) has been demonstrated by several ...