Browsing Internal Medicine by Subject "Reactive oxygen species"

Browsing Internal Medicine by Subject "Reactive oxygen species"

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  • Cigarette smoke condensate attenuates phorbol ester-mediated neutrophil extracellular trap formation 
    Bokaba, Refilwe Philadelphia; Anderson, Ronald; Theron, Annette J.; Tintinger, Gregory Ronald (Makerere University Medical School, 2017-09)
    BACKGROUND : Neutrophil extracellular traps (NETs) constitute a network of chromatin fibres containing histone and antimicrobial peptides that are released by activated neutrophils. NETs protect the host against infection ...
  • Effects of moxifloxacin on human neutraphil and T-lymphocyte functions in vitro 
    Potjo, Moliehi; Cockeran, Riana; Theron, Annette J.; Feldman, Charles; Anderson, Ronald (Molecular Diversity Preservation International, 2010)
    Moxifloxacin is useful in the treatment of respiratory infections, including community-acquired pneumonia, and also shows promise in the treatment of tuberculosis, a clinical setting which necessitates extended administration ...
  • Neutrophil extracellular traps and their role in health and disease 
    Nel, Jan Gert; Theron, Annette J.; Pool, Roger; Durandt, Chrisna; Tintinger, Gregory Ronald; Anderson, Ronald (AOSIS OpenJournals, 2016-01)
    The human innate immune system is indispensable for protection against potentially invasive microbial and viral pathogens, either neutralising them or containing their spread until effective mobilisation of the slower, adaptive ...
  • Pneumolysin activates neutrophil extracellular trap formation 
    Nel, Jan Gert; Theron, Annette J.; Durandt, Chrisna; Tintinger, Gregory Ronald; Pool, Roger; Mitchell, Timothy J.; Feldman, Charles; Anderson, Ronald (Wiley, 2016-06)
    The primary objective of the current study was to investigate the potential of the pneumococcal toxin, pneumolysin (Ply), to activate neutrophil extracellular trap (NET) formation in vitro. Isolated human blood neutrophils ...