Browsing Internal Medicine by Subject "Community-acquired pneumonia"

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Pneumolysin mediates platelet activation in vitro

Nel, Jan Gert; Durandt, Chrisna; Mitchell, Timothy J.; Feldman, Charles; Anderson, Ronald; Tintinger, Gregory Ronald (Springer, 2016-08)

This study has explored the role of the pneumococcal toxin, pneumolysin (Ply), in activating human platelets. Following exposure to Ply [10–80 nanograms (ng)/ml], platelet activation and cytosolic Ca2+ concentrations ...
Soluble triggering receptor expressed on myeloid cells in sputum of patients with community-acquired pneumonia or pulmonary tuberculosis : a pilot study

Tintinger, Gregory Ronald; Van der Merwe, J.J.; Ficki, H.; Rheeder, Paul; Feldman, Charles; Anderson, Ronald (Springer, 2012-01)

Soluble triggering receptor expressed on myeloid cells is upregulated on the surface of inflammatory cells in the presence of bacterial infections apparently excluding those due to Mycobacterium tuberculosis. Therefore, ...

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