Browsing Internal Medicine by Author "Ker, James A."

Browsing Internal Medicine by Author "Ker, James A."

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  • Obstructive sleep apnoea and hypertension 
    Ker, James A. (New Media Publishing, 2018-03)
    OSAHS raises the mean 24-hour blood pressure (BP) by 5mmHg to 10mmHg and the blood pressure increase is more in those patients with >20% arterial oxygen desaturation per hour of sleep. This rise in mean BP can lead to 20% ...
  • Pharmaceutical drugs in the treatment of STEMI 
    Ker, James A. (New Media Publishing, 2016-08)
    Our concept of ST-segment Elevated Myocardial Infarction (STEMI) refers to when coronary blood supply decreases abruptly after a thrombotic occlusion. The underlying mechanism leading to the thrombotic event is an unstable ...
  • The reliability of chest radiographs in predicting left atrial enlargement 
    Quinton, S.J. (Susanna Jacoba); Ker, James A.; Rheeder, Paul; Deffur, A. (Clinics Cardiv, 2010-09)
    INTRODUCTION: Estimates of left atrial size in patients with suspected cardiac disease play an important role in predicting prognosis and events, as well as treatment decisions. Two methods are commonly used to estimate ...
  • Rheumatoid arthritis and risk of cardiovascular disease 
    Meyer, Pieter Willem Adriaan; Anderson, Ronald; Ker, James A.; Ally, Mahmood Moosa Tar Mahomed (Clinics Cardive, 2018-09)
    In developing countries, rheumatoid arthritis (RA) remains a seriously under-prioritised disease, particularly among the underprivileged, often resulting in presentation of patients late in the course of their disease, ...
  • The risk of CAD in women 
    Ker, James A. (New Media Publishing, 2018-08)
    A therosclerotic cardiovascular disease (CVD) is a chronic disorder that develops throughout life causing no symptoms. However, with progression to an advanced stage, symptoms of ischaemia appear, terminating in acute ...
  • Secondary hypertension 
    Ker, James A. (South African Academy of Family Practice, 2011-09)
    Secondary hypertension is rare and the diagnosis may be challenging although, on occasion, there are clinical features indicative of a specific underlying cause. The more commonly encountered causes include renal parenchymal ...
  • Thrombotic complications 
    Ker, James A. (New Media Publishing, 2015-09)
    There have been significant advances in the treatment of heart failure (HF) with a reduction in mortality. Despite this improvement in mortality, HF still has a bad prognosis and research is ongoing to find ways to improve ...
  • The treatment of cholesterol : issues, effects and targets 
    Ker, James A. (South African Academy of Family Practice/Primary Care, 2010-11)
    Statins are the most powerful cholesterol lowering drugs currently available. Statins inhibit 3-hydroxy-3-methylglutaryl-coenzyme A (HMG CoA) reductase, which leads to reduced cholesterol synthesis. In addition, low-density ...
  • Under pressure to keep it ticking 
    Ker, James A. (New Media Publishing, 2017-11)
    Most patients with hypertension can develop heart failure. In the Framing Heart Study hypertension preceded the development of heart failure in about 91% of new-onset heart failure during at least mean follow-up of 14.1 ...
  • Unilateral atrial fibrillation - how common is atrial divorce? 
    Ker, James A. (Royal College of Physicians of Edinburgh, 2017-06)
    Atrial brillation is the most common pathologic supraventricular tachycardia. It has many causes, is an expensive disease, impairs quality of life and leads to an increased risk of death. Atrial dissociation is ...
  • An unresolved problem 
    Ker, James A. (Media 24, 2015-04)
    The impact of hypertension as a risk factor on the occurrence of cardiovascular disease clinical events should not be underestimated.
  • Vitamin D in acute and chronic disease 
    Ker, James A. (Health and Medical Publishing Group, 2011)
    It has emerged over the past 10-20 years that the change in our lifestyle has led to the widespread deficiency of vitamin D. These lifestyle changes include the avoidance of sunlight (voluntary or greater reliance on ...