Browsing Internal Medicine by Title

Browsing Internal Medicine by Title

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  • The antimicrobial effect of colistin methanesulfonate on Mycobacterium tuberculosis in vitro 
    Van Breda, Shane Vontelin; Buys, Antoinette; Apostolides, Zeno; Nardell, Edward Anthony; Stoltz, Anton Carel (Elsevier, 2015-07)
    Polymyxins have previously been described to have activity against M. tuberculosis (MTB), but further research was abandoned due to systemic toxicity concerns to achieve the required MIC. Colistin methanesulfonate (CMS), ...
  • Apoptotic profiling of chronic myeloid leukaemia patients' platelets ex vivo before and after treatment with Imatinib 
    Repsold, Lisa; Pool, Roger; Karodia, Mohammed; Tintinger, Gregory Ronald; Becker, Piet J.; Joubert, Anna Margaretha (Wiley, 2021-06)
    Chronic myeloid leukaemia (CML) is a malignancy of the haematopoietic stem cells. The first line of treatment for CML, especially in developing countries, remains the first-generation tyrosine kinase inhibitor, Imatinib. ...
  • The arterial duct and the right aortic arch : telescope into the prenatal defective heart 
    Ker, James A. (Springer, 2021-12)
    Progress in the understanding, diagnosis and treatment of congenital cardiovascular anomalies began when dr Helen Taussig founded the pediatric cardiology clinic at the Johns Hopkins Hospital in Baltimore in 1930 and the ...
  • The association between elevated troponin levels and all cause 30 day mortality in critically ill patients seen at an Academic Hospital – a prospective cohort study 
    Joseph, Darren; Ker, James A.; Rheeder, Paul; Ueckermann, Veronica (University of Leicester, 2017-03-07)
    PURPOSES : Elevated cardiac troponins have been shown to be associated with mortality in critical care, but its utility is not well established, especially in the setting of renal failure. This study aimed to examine the ...
  • Association between gestational diabetes and biomarkers : a role in diagnosis 
    Adam, Sumaiya; Pheiffer, Carmen; Dias, Stephanie Charmaine; Rheeder, Paul (Taylor and Francis, 2018)
    BACKGROUND : We investigated the association between markers of insulin resistance, chronic inflammation, and adipokines and GDM. METHODS : In our case-cohort study in Johannesburg we included women with GDM and controls. ...
  • Association between HIV replication and serum leptin levels : an observational study of a cohort of HIV-1-infected South African women 
    Azzoni, Livio; Crowther, Nigel J.; Firnhaber, Cynthia; Foulkes, Andrea S.; Yin, Xiangfan; Glencross, Deborah; Gross, Robert; Kaplan, Mitch D.; Papasavvas, Emmanouil; Schulze, Doreen; Stevens, Wendy; Van der Merwe, Maria-Teresa; Waisberg, Rita; Sanne, Ian; Montaner, Luis J. (BioMed Central, 2010-09)
    BACKGROUND: Advanced HIV infection can result in lipoatrophy and wasting, even in the absence of ongoing opportunistic infections, suggesting that HIV may directly affect adipose tissue amount and distribution. METHODS: ...
  • Association of Adipose tissue inflammation with histologic severity of nonalcoholic fatty liver disease 
    Du Plessis, Johannie; Van Pelt, Jos; Korf, Hannelie; Mathieu, Chantal; Van der Schueren, Bart; Lannoo, Matthias; Oyen, Tom; Topal, Baki; Fetter, Gary; Nayler, Simon; Van der Merwe, Tessa; Windmolders, Petra; Van Gaal, Luc; Verrijken, An; Hubens, Guy; Gericke, Martin; Cassiman, David; Francque, Sven; Nevens, Frederik; Van der Merwe, Schalk (Elsevier, 2015-09)
    BACKGROUND & AIMS : The prevalence of nonalcoholic fatty liver disease (NAFLD) has increased with the obesity pandemic. We analyzed the transcriptional profiles of subcutaneous adipose tissue (SAT) and visceral adipose ...
  • Attitudes toward plagiarism : the case of undergraduate health sciences students at the University of Pretoria 
    Matsebetlela, E.M. (Emmanuel); Kuhudzai, Anesu Gelfand (CSSALL Publishers, 2018)
    The primary aim of the study on which this article is based was to investigate undergraduate health sciences students’ perceptions, attitudes to and awareness of plagiarism at the University of Pretoria in South Africa. ...
  • Autoimmune hepatitis : a clinical study 
    Buchel, Elwin Herbert (University of Pretoria, 2011-01-10)
    This study involved the analysis of 112 patients with autoimmune hepatitis (AIH), during which process several specific issues or problems were identified. One subgroup included pregnant patients, and another patients ...
  • Autonomic impairment in rheumatoid arthritis 
    Janse van Rensburg, Dina Christina; Ker, James A.; Grant, C.C. (Catharina Cornelia); Fletcher, Lizelle (Blackwell Publishing, 2012-08)
    AIM: To determine if there is a difference between autonomic cardiac control as measured by heart rate variability (HRV) in women with rheumatoid arthritis (RA) compared to a healthy control group. METHODS: The RA group ...
  • Autonomic response to exercise as measured by cardiovascular variability 
    Grant, C.C. (Catharina Cornelia); Ker, James A. (Health and Medical Publishing Group, 2008)
    MOTIVATION: There is growing interest in the use of cardiovascular variability indicators as measures of autonomic activity,even though reported results are not always comparable or as expected. This review aims to determine ...
  • Bariatric surgery : risks and recommendations for the prevention of perioperative thromboembolism 
    Murphy, A.; Van der Merwe, Maria-Teresa (Health and Medical Publishing Group, 2010)
    No abstract available.
  • Basedow paraplegia : a possible misnomer 
    Smith, Lizl; Kemp, Tanja; Van der Meyden, C.H. (Kees); Schutte, Clara-Maria (Health and Medical Publishing Group, 2015-10)
    Thyrotoxic myopathy frequently occurs in clinical practice; however, the association of hyperthyroidism with a flaccid, areflexic paraplegia, so-called Basedow paraplegia, appears to represent a controversial and doubtful ...
  • Beneficial and harmful interactions of antibiotics with microbial pathogens and the host innate immune system 
    Anderson, Ronald; Tintinger, Gregory Ronald; Cockeran, Riana; Potjo, Moliehi; Feldman, Charles (Molecular Diversity Preservation International, 2010-05)
    In general antibiotics interact cooperatively with host defences, weakening and decreasing the virulence of microbial pathogens, thereby increasing vulnerability to phagocytosis and eradication by the intrinsic antimicrobial ...
  • Beta blockers and their combinations in the management of hypertension 
    Ker, James A. (South African Academy of Family Practice/Primary Care, 2012-09)
    Beta blockers have been prescribed for the treatment of primary hypertension for a very long time. Currently, it is doubtful whether this is still a good idea. In fact, many are of the opinion that beta blockers should be ...
  • Broken heart syndrome 
    Ker, James A. (Media 24, 2015)
    Takotsubo was first described in Japan in 1990, but subsequently it was described globally and in 2013 there were 1879 publications on the subject. The main characteristic is transient reversible systolic dysfunction of ...
  • Burning issues in acute heart failure management 
    Ker, James A.; Outhoff, Kim (Medpharm Publications, 2019-12)
    In general, heart failure is the end-stage manifestation of cardiovascular disease and is an important and increasing cause of morbidity worldwide. Acute heart failure, whether of new onset or an exacerbation of chronic ...
  • Burning issues in blood pressure control 
    Ker, James A.; Outhoff, Kim (OASIS, 2019-03)
    Globally more than 1 billion people have hypertension and it is predicted that because of ageing populations and increasing sedentary lifestyles, this figure will rise to about 1.5 billion by 2025. Elevated blood pressure ...
  • Burning issues in the prevention of heart failure 
    Ker, James A.; Outhoff, Kim (MedPharm Publications, 2020-08)
    Chronic heart failure is common, debilitating, and often the culmination of pervasive cardiovascular insults that systematically undermine the heart’s circulatory capacity and invoke counterproductive neuro-hormonal ...
  • Burning issues in the prevention of heart failure 
    Ker, James A.; Outhoff, Kim (AOSIS Open Journals, 2019-07)
    Chronic heart failure is common, debilitating, and often the culmination of pervasive cardiovascular insults that systematically undermine the heart’s circulatory capacity and invoke counterproductive neuro-hormonal ...