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Browsing Research Articles (Chemical Pathology) by Type "Article"
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Punchoo, Rivak; Dreyer, Greta; Pillay, Tahir S.
(MDPI, 2023-03)
Preclinical studies show that the anticancer actions of vitamin D metabolites are mediated by apoptosis, inhibition of cell proliferation and induction of cell cycle arrest. Cervical cancer cells express an autocrine vitamin ...
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Olivier, Brenda J.; Bond, Robert P.; Van Zyl, Walda B.; Delport, Maraliese; Slavik, Tomas; Ziady, Christopher; Terhaar sive Droste, Jochim S.; Lastovica, Albert; Van der Merwe, Schalk Willem
(American Society for Microbiology, 2006-02)
Our study aimed to evaluate the oral cavity as a reservoir from where Helicobacter pylori may be transmitted. Histology and PCR amplification were performed. Eighty-four percent of the stomach biopsies tested positive; ...
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Van Deventer, B.S.; Makhoba, Aubrey Musa; Du Toit-Prinsloo, L.; Van Niekerk, Chantal
(Clinics Cardive Publishing, 2022-09)
Sudden unexpected infant death (SUDI) is reported to be
an extraordinarily high burden in sub-Saharan Africa, with
the incidence rate in South Africa among the highest in the
world. It is common for the cause of many ...
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Pillay, Tahir S.; Muyldermans, Serge
(Korean Society for Laboratory Medicine, 2021)
Antibodies have proven to be central in the development of diagnostic methods over decades, moving from polyclonal antibodies to the milestone development of monoclonal
antibodies. Although monoclonal antibodies play a ...
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Oosthuizen, Nicholette M.
(Health and Medical Publishing Group, 2012-07)
Skill in interpreting biochemical data to correctly identify and treat acid-base disorders is an essential competency for clinicians. Studies have, however, shown that proficiency in this area is lacking and that performance ...
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Delport, Rhena
(Clinics Cardive, 2018-01)
Both patient and health-system delays contribute to delays in restoring myocardial perfusion. Patient-related delays constitute the time from onset of symptoms to the call for help, and onset of symptoms to first medical ...
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Govender, Radha; De Greef, Jacques; Delport, Rhena; Becker, Piet J.; Vermaak, William J.H.
(Clinics Cardiv, 2008-05)
AIM: Ischaemia-modified albumin (IMA), as measured by the albumin-cobalt binding (ACB) test®, has been cleared by the US Food and Drug administration as a biomarker to exclude the presence of myocardial ischaemia in patients. ...
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Van Deventer, Barbara Stroh; Du Toit-Prinsloo, Lorraine; Van Niekerk, Chantal
(Health and Medical Publishing Group, 2022-12)
Cardiovascular diseases (CVDs) are ever-increasing, and as such are considered to be one of the most concerning public health burdens worldwide. They remain the leading cause of death across the world (~17.7 million deaths ...
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Satekge, Tumelo M.; Kiabilua, Olivia; Van Biljon, Gertruida; Pillay, Komala; Pillay, Tahir S.
(International Federation of Clinical Chemistry and Laboratory Medicine, 2017)
Congenital nephrotic syndrome is a rare inherited
disorder arising from defects in the proteins of the
cells in the glomerular basement membrane and develops
either in utero or at birth. The clinical presentation
is ...
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Delport, Rhena; Bornman, Maria S. (Riana); MacIntyre, Una Elizabeth; Oosthuizen, Nicholette M.; Becker, Piet J.; Aneck-Hahn, Natalie Hildegard; De Jager, Christiaan
(National Institute of Environmental Health Sciences (NIEHS), 2010-12)
BACKGROUND: The insecticide dichlorodiphenyltrichloroethane (DDT) has been used for malaria vector control in the northern and eastern parts of the Vhembe District of Limpopo Province, South Africa, since 1945. Bioaccumulation ...
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Bhoora, Sachin; Pather, Yuvelia; Marais, Sumari; Punchoo, Rivak
(MDPI, 2020-02)
Vitamin D has displayed anti-cancer actions in numerous in vitro studies. Here,
we investigated the anti-cancer actions of cholecalciferol, a vitamin D precursor, on a metastatic
cervical cancer cell line, namely, CaSki. ...
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Patil, Mangesh; Choudhari, Amit S.; Pandita, Savita; Raina, Prerna; Kaul-Ghanekar, Ruchika
(Medknow, 2017-10-11)
BACKGROUND : The altered expression of histone deacetylase family member
8 (HDAC8) has been found to be linked with various cancers, thereby making
its selective inhibition a potential strategy in cancer therapy. ...
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Mandave, P.C.; Kuvalekar, A.A.; Mantri, N.L.; Islam, Md Ataul; Ranjekar, P.K.
(CIRAD, 2017-05)
INTRODUCTION - Proanthocyanidins (PAs) are a
group of polyphenolic secondary metabolites synthesized
in plants via flavonoid pathway. Strawberry
(Fragaria × ananassa Duch.) is a rich source of flavonoids
and proanthocyanins, ...
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Pillay, Tahir S.; Turzyniecka, Magdalena J.
(Health and Medical Publishing Group, 2013-06)
No abstract available..
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Chale-Matsau, Bettina; Van Niekerk, Chantal; Kemp, Tanja; Pillay, Tahir S.
(American Association for Clinical Chemistry, 2018-03)
A 33-year-old woman presented for the first time at
the age of 9 years with recurrent seizures and was subsequently
treated for epilepsy for 2 years. At 11 years of
age, it was noted that the patient had hypocalcemia
...
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De Greef, Jacques; Govender, Radha; Vermaak, William J.H.; Perumal, Nalini S.; Libhaber, Elena; Vangu, Mboyo-Di-Tamba
(Clinics Cardiv, 2007-11)
BACKGROUND: B-type natriuretic peptide(BNP) and the inactive amino-terminal pro-B-type natriuretic peptide (NT-proBNP) have a prognostic value in heart failure and in myocardial infarction. There has been some evidence ...
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Parson, Walther; Strobl, Christina; Huber, Gabriela; Zimmermann, Bettina; Gomes, Sibylle M.; Souto, Luis; Fendt, Liane; Delport, Rhena; Langit, Reina; Wootton, Sharon; Lagacé, Robert; Irwin, Jodi
(Elsevier, 2013-09)
Insights into the human mitochondrial phylogeny have been primarily achieved by sequencing full mitochondrial genomes (mtGenomes). In forensic genetics (partial) mtGenome information can be used to assign haplotypes to ...
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Bangalee, Avania; Bhoora, Sachin; Punchoo, Rivak
(AOSIS, 2021-10)
Serological tests based on the enzyme immunoassay (EIA) are the primary tool for the diagnosis of human immunodeficiency virus (HIV) in adults and have rapidly evolved to quicker, affordable and more accurate test formats ...
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Delport, Rhena
(Clinics Cardiv, 2009-01)
This review discusses the 1987 article by Wyndham, Seftel, Pilcher and Baker on familial hypercholesterolaemia (FH) and myocardial infarction (MI) in young Afrikaners, in terms of the significance at the time of publication, ...
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Punchoo, Rivak; Zhou, Esther; Bhoora, Sachin
(MyJove Corporation, 2021-08-26)
Apoptosis biomarkers were investigated in actinomycin D-treated SiHa cervical cancer
cells using a benchtop flow cytometer. Early biomarkers (Annexin V and mitochondrial
membrane potential) and late biomarkers (caspases ...