Browsing Research Articles (Paediatrics and Child Health) by Title

Browsing Research Articles (Paediatrics and Child Health) by Title

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  • Malignant extracranial germ cell tumours : a first national report by the South African Children's Cancer Study Group 
    Hendricks, Marc; Cois, Annibale; Geel, Jennifer; Du Plessis, Johan; Bassingthwaighte, Mairi; Naidu, Gita; Rowe, Biance; Buchner, Ane; Omar, Fareed E.; Thomas, Karla; Uys, Ronelle; Van Zyl, Anel; Van Heerden, Jaques; Mahlachana, Ngoakoana; Vermeulen, Johani; Davidson, Alan; Frazier, A. Lindsay; Donald, Kirsty; Kruger, Mariana (Wiley, 2022-05)
    OBJECTIVE : To determine the overall survival (OS) and prognostic factors influencing outcomes in children and adolescents with malignant extracranial germ cell tumours (MEGCTs) in preparation for the development of a ...
  • Management guidelines for acute infective diarrhoea/gastroenteritis in infants 
    Wittenberg, Dankwart F. (Health and Medical Publishing Group, 2012-02)
    BACKGROUND: Acute onset vomiting and diarrhoea is one of the most common illnesses of infancy, and is second only to respiratory illnesses as a cause of childhood deaths worldwide. Existing guidelines for management of ...
  • Management of acute fever in children : consensus recommendations for community and primary healthcare providers in Sub-Saharan Africa 
    Green, Robin J.; Webb, David; Jeena, Prakash Mohan; Wells, Mike; Butt, Nadia; Hangoma, Jimmy Mapenzi; Moodley, Rajatheran Sham; Maimin, Jackie; Wibbelink, Margreet; Mustafa, Fatima (Elsevier, 2021-06)
    Fever is one of the most common reasons for unwell children presenting to pharmacists and primary healthcare practitioners. Currently there are no guidelines for assessment and management of fever specifically for community ...
  • Management of acute fever in children : guideline for community healthcare providers and pharmacists 
    Green, Robin J.; Jeena, Prakash M.; Kotze, S.; Lewis, Humphrey; Webb, D.; Wells, M. (Health and Medical Publishing Group, 2013-12)
    Fever is a normal physiological response to illness that facilitates and accelerates recovery. Although it is often associated with a self-limiting viral infection in children, it may also be a presenting symptom of more ...
  • Management of community-acquired pneumonia in children : South African Thoracic Society guidelines (Part 3) 
    Reubenson, G.; Avenant, Theunis Johannes; Moore, D.P.; Itzikowitz, G; Andronikou, S.; Cohen, C.; Green, Robin J.; Jeena, P.; Masekela, P.; Masekela, R.; Nicol, M.P.; Pillay, A.; Madhi, S.A.; Zar, Heather J.; Argent, A.C. (Health and Medical Publishing Group, 2020-08)
    BACKGROUND. Pneumococcal conjugate vaccine (PCV) administration and other advances have been associated with a shift in the aetiological spectrum of community-acquired pneumonia, necessitating reconsideration of empiric ...
  • Management of severe acute malnutrition 
    Cloete, Jeane (Health and Medical Publishing Group, 2015-07)
    Malnutrition remains a global health concern and contributes significantly to childhood mortality. Nearly half of all deaths in children <5 years of age are attributed to undernutrition, especially in developing countries. ...
  • Management of severe aortic valve stenosis in the neonate 
    Mitchell, Belinda J.; Brown, S.C. (South African Heart Association, 2014)
    Aortic valve stenosis (AS) causing obstruction to the left ventricular outfl ow, and hence reduction of the cardiac output, remains a therapeutic challenge for paediatric cardiologists and cardiothoracic surgeons. Infants ...
  • Managing and preventing childhood pneumonia in South Africa : updated South African guidelines 
    Green, Robin J.; Zar, Heather J.; Madhi, Shabir A. (Health and Medical Publishing Group, 2020-08)
    The two articles in this edition of CME follow up on those in the previous edition, i.e. epidemiology/aetiology and diagnosis of community-acquired pneumonia (CAP) in children. The articles in this issue cover recommendations ...
  • Markers of cognitive function in individuals with metabolic disease : Morquio syndrome and tyrosinemia type III 
    Blundell, James; Frisson, Steven; Chakrapani, Anupam; Kearney, Shauna; Vijay, Suresh; MacDonald, Anita; Gissen, Paul; Hendriksz, Christian J.; Olson, Andrew (Routledge, 2018)
    We characterized cognitive function in two metabolic diseases. MPS–IVa (mucopolysaccharidosis IVa, Morquio) and tyrosinemia type III individuals were assessed using tasks of attention, language and oculomotor function. ...
  • Mechanisms of mitochondrial dysfunction in lysosomal storage disorders : a review 
    Stepien, Karolina M.; Roncaroli, Federico; Turton, Nadia; Hendriksz, Christian J.; Roberts, Mark; Heaton, Robert A.; Hargreaves, Iain (MDPI, 2020-08)
    Mitochondrial dysfunction is emerging as an important contributory factor to the pathophysiology of lysosomal storage disorders (LSDs). The cause of mitochondrial dysfunction in LSDs appears to be multifactorial, although ...
  • The medical dictionary ‘tongue-in-cheek' edition 
    Green, Robin J.; Hoffmann, Kelly S.; Pentz, Adele (Health and Medical Publishing Group, 2013-12)
    Medical communication is often so formal, and one can't help thinking that sometimes a more light-hearted approach would be nice. We recently attended an advanced paediatric life support course in Pretoria (may we suggest ...
  • Metabolic alterations in mothers living with HIV and their HIV-exposed, uninfected infants 
    Du Toit, Louise de Villiers; Mason, Shayne; Van Reenen, Mari; Rossouw, Theresa; Louw, Roan (MDPI, 2024-02)
    HIV-exposed, uninfected (HEU) children present with suboptimal growth and a greater susceptibility to infection in early life when compared to HIV-unexposed, uninfected (HUU) children. The reasons for these findings are ...
  • Metabolomics of urinary organic acids in respiratory chain deficiencies in children 
    Reinecke, Carolus J.; Koekemoer, Gerhard; Van der Westhuizen, Francois H.; Louw, Roan; Lindeque, Jeremie Z.; Mienie, Lodewikus J.; Smuts, Izelle (Springer, 2012-04)
    Metabolomic analysis of the urinary organic acids from 39 selected children with defined respiratory chain deficiencies (RCDs) was performed using untargeted gas chromatography–mass spectrometry, revealing the presence ...
  • Metastatic calcification as a result of extensive bone metastases in a paediatric patient with parameningeal embryonal rhabdomyosarcoma 
    Ismail, Farzanah; Lockhat, Zarina I.; Khan, Nausheen; Van de Werke, Irma; Adroos, Narosha; Sathekge, Mike Machaba; Kruger, Mariana; Reynders, David (Health and Medical Publishing Group, 2008-04)
    We present a case of parameningeal embryonal rhabdomyosarcoma with the primary lesion arising in the middle and inner ear, with associated diffuse skeletal metastases and metastatic calcifications.
  • Method of delivery, the microbiome and neurodevelopment  
    Lamb, Gregory V.; Van Niekerk, Andre; Green, Robin J. (Allergy Society of South Africa, 2017-09)
    Caesarean sections, and especially elective Caesarean sections, are on the increase worldwide. The grey-matter volume of the foetal brain undergoes a linear increase of 1,4% per week from 29 weeks until 40 weeks of ...
  • The microbiome in chronic inflammatory airway disease : a threatened species 
    Green, Robin J.; Van Niekerk, Andre; Jeevarathnum, A.C.; Feldman, Charles; Richards, Guy A. (Health and Medical Publishing Group, 2016-08)
    The human body is exposed to a multitude of microbes and infectious organisms throughout life. Many of these organisms colonise the skin, gastrointestinal tract (GIT) and airway. We now recognise that this colonisation ...
  • Missed opportunities along the prevention of mother-to-child transmission services cascade in South Africa : uptake, determinants, and attributable risk (the SAPMTCTE) 
    Woldesenbet, Selamawit A.; Jackson, Debra J.; Lombard, Carl; Dinh, Thu-ha; Puren, Adrian; Sherman, Gayle; Ramokolo, Vundli; Doherty, Tanya; Mogashoa, Mary M.; Bhardwaj, S.; Chopra, Mickey; Shaffer, Nathan; Pillay, Yogan; Goga, Ameena Ebrahim; Anglewicz, Philip (Public Library of Science, 2015-07-06)
    Objectives We examined uptake of prevention of mother-to-child HIV transmission (PMTCT) services, predictors of missed opportunities, and infant HIV transmission attributable to missed opportunities along the PMTCT ...
  • Missed opportunities for early infant HIV diagnosis : results of a national study in South Africa 
    Woldesenbet, Selamawit A.; Jackson, Debra J.; Goga, Ameena Ebrahim; Crowley, Siobhan; Doherty, Tanya; Mogashoa, Mary M.; Dinh, Thu-Ha; Sherman, Gayle G. (Lippincott Williams and Wilkins, 2015-03)
    BACKGROUND : Services to diagnose early infant HIV infection should be offered at the 6-week immunization visit. Despite high 6-week immunization attendance, the coverage of early infant diagnosis (EID) is low in many ...
  • Missing HIV prevention opportunities in South African children - a 7-year review 
    Feucht, Ute Dagmar; Meyer, Anell; Kruger, Mariana (BioMed Central, 2014-12)
    BACKGROUND : The prevention of mother-to-child transmission (PMTCT) program in South Africa is now successful in ensuring HIV-free survival for most HIV-exposed children, but gaps in PMTCT coverage remain. The study ...
  • Mitochondrial DNA parameters in blood of infants receiving lopinavir/ritonavir or lamivudine prophylaxis to prevent breastfeeding transmission of HIV-1 
    Monnin, Audrey; Nagot, Nicolas; Peries, Marianne; Vallo, Roselyne; Meda, Nicolas; Singata-Madliki, Mandisa; Tumwine, James K.; Kankasa, Chipepo; Ngandu, Nobubelo Kwanele; Goga, Ameena Ebrahim; Reynier, Pascal; Tylleskar, Thorkild; Van de Perre, Philippe; Moles, Jean-Pierre (MDPI, 2020-09)
    Children who are human immunodeficiency virus (HIV)-exposed but uninfected (CHEU) accumulate maternal HIV and antiretroviral exposures through pregnancy, postnatal prophylaxis, and breastfeeding. Here, we compared the ...