Browsing Nuclear Medicine by Subject "Hypoxia"

Now showing items 1-2 of 2

Correlation between [68Ga]Ga-FAPI-46 PET imaging and HIF-1 immunohistochemical analysis in cervical cancer: proof-of-concept

Mokoala, K.M.G. (Kgomotso); Lawal, Ismaheel Opeyemi; Maserumule, Letjie; Bida, Meshack; Maes, Alex; Ndlovu, Honest; Reed, Janet D.; Mahapane, Johncy; Davis, Cindy; Van de Wiele, Christophe; Popoola, Gbenga; Giesel, Frederik L.; Vorster, Mariza; Sathekge, Mike Machaba (MDPI, 2023-08-03)

Hypoxia leads to changes in tumor microenvironment (upregulated CAFs) with resultant aggressiveness. A key factor in the physiological response to hypoxia is hypoxia-inducible factor-1alpha (HIF-1 ). [68Ga]Ga-FAPI PET ...
A prospective investigation of tumor hypoxia imaging with 68Ga-nitroimidazole PET/CT in patients with carcinoma of the cervix uteri and comparison with 18F-FDG PET/CT : correlation with immunohistochemistry

Mokoala, K.M.G. (Kgomotso); Lawal, Ismaheel Opeyemi; Maserumule, L.C. (Letjie); Hlongwa, Khanyisile N.; Ndlovu, Honest; Reed, Janet D.; Bida, Nndweleni Meshack; Maes, Alex; Van de Wiele, Christophe; Mahapane, Johncy; Davis, Cindy; Jeong, Jae Min; Popoola, Gbenga O.; Vorster, Mariza; Sathekge, Mike Machaba (MDPI, 2021-02-12)

Hypoxia in cervical cancer has been associated with a poor prognosis. Over the years 68Ga labelled nitroimidazoles have been studied and have shown improved kinetics. We present our initial experience of hypoxia Positron ...

Now showing items 1-2 of 2

Search UPSpace