Browsing Immunology by UP Author "Madzime, Morris"

Browsing Immunology by UP Author "Madzime, Morris"

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  • Dolutegravir potentiates platelet activation by a calcium-dependent, ionophore-like mechanism 
    Madzime, Morris; Theron, Annette J.; Anderson, Ronald; Tintinger, Gregory; Steel, Helen C.; Meyer, Pieter Willem Adriaan; Nel, Jan Gert; Feldman, Charles; Rossouw, Theresa M. (Taylor and Francis, 2022)
    Please read abstract in the article.
  • Interactions of HIV and antiretroviral therapy with neutrophils and platelets 
    Madzime, Morris; Rossouw, Theresa M.; Theron, Annette J.; Anderson, Ronald; Steel, Helen C. (MDPI, 2021-03-12)
    Neutrophils are important components of the innate immune system that mediate pathogen defense by multiple processes including phagocytosis, release of proteolytic enzymes, production of reactive oxygen species, and ...
  • Pro-inflammatory interactions of dolutegravir with human neutrophils in an in vitro study 
    Theron, Annette J.; Anderson, Ronald; Madzime, Morris; Rossouw, Theresa M.; Steel, Helen C.; Meyer, Pieter Willem Adriaan; Cholo, Moloko C.; Kwofie, Luyanda Laura Illicia; Feldman, Charles; Tintinger, Gregory (MDPI, 2022-12-19)
    There is increasing awareness of an association between the uptake of the HIV integrase inhibitor, dolutegravir, in first-line antiretroviral regimens with unusual weight gain and development of the metabolic syndrome, ...