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Browsing Immunology by Subject "Immune checkpoint inhibitors"
Now showing items 1-4 of 4
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(Elsevier, 2021-12)Immune checkpoint inhibitors are a new class of oncologic drugs that act via the inhibition of check- points, thereby unlocking the immune system to attack cancer cells. Their emergence has radically changed the concept ...
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(Springer, 2020-12)The immune checkpoints associated with the CTLA-4 and PD-1 pathways are critical modulators of immune activation. These pathways dampen the immune response by providing brakes on activated T cells, thereby ensuring more ...
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Realizing the clinical potential of immunogenic cell death in cancer chemotherapy and radiotherapy (MDPI, 2019-02)Immunogenic cell death (ICD), which is triggered by exposure of tumor cells to a limited range of anticancer drugs, radiotherapy, and photodynamic therapy, represents a recent innovation in the revitalized and burgeoning ...
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Role of the neutrophil in the pathogenesis of advanced cancer and impaired responsiveness to therapy (MDPI Publishing, 2020-04-01)Notwithstanding the well-recognized involvement of chronic neutrophilic inflammation in the initiation phase of many types of epithelial cancers, a growing body of evidence has also implicated these cells in the pathogenesis ...
Now showing items 1-4 of 4