Browsing Immunology by Author "Roskams, Tania"

Browsing Immunology by Author "Roskams, Tania"

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  • Activated intestinal macrophages in patients with cirrhosis release NO and IL- 6 that may disrupt intestinal barrier function 
    Du Plessis, Johannie; Vanheel, Hanne; Janssen, Carl E.I.; Roos, Leonie; Slavik, Tomas; Stivaktas, Paraskevi Irene; Nieuwoudt, Martin J.; Van Wyk, Stefan George; Vieira, Warren Antonio; Pretorius, Etheresia; Beukes, Mervyn; Farré, Ricard; Tack, Jan; Laleman, Wim; Fevery, Johan; Nevens, Frederik; Roskams, Tania; Van der Merwe, Schalk Willem (Elsevier, 2013-06)
    BACKGROUND & AIMS : Bacterial infections commonly occur in decompensated cirrhosis resulting from bacterial translocation from the intestine. We studied the role of intestinal macrophages and the epithelial barrier in ...
  • CD14+ macrophages that accumulate in the colon of African AIDS patients express pro-inflammatory cytokines and are responsive to lipopolysaccharide 
    Cassol, Edana; Rossouw, Theresa M.; Malfeld, Susan; Mahasha, Phetole Walter; Slavik, Tomas; Seebregts, Christopher J.; Bond, Robert P.; Du Plessis, Johannie; Janssen, Carl E.I.; Roskams, Tania; Nevens, Frederik; Alfano, Massimo; Poli, Guido; Van der Merwe, Schalk Willem (BioMed Central, 2015-10-17)
    BACKGROUND : Intestinal macrophages are key regulators of inflammatory responses to the gut microbiome and play a central role in maintaining tissue homeostasis and epithelial integrity. However, little is known about the ...