Browsing Immunology by Author "Poli, Guido"

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CD14+ macrophages that accumulate in the colon of African AIDS patients express pro-inflammatory cytokines and are responsive to lipopolysaccharide

Cassol, Edana; Rossouw, Theresa M.; Malfeld, Susan; Mahasha, Phetole; Slavik, Tomas; Seebregts, Christopher J.; Bond, Robert P.; Du Plessis, Johannie; Janssen, Carl E.I.; Roskams, Tania; Nevens, Frederik; Alfano, Massimo; Poli, Guido; Van der Merwe, Schalk Willem (BioMed Central, 2015-10-17)

BACKGROUND : Intestinal macrophages are key regulators of inflammatory responses to the gut microbiome and play a central role in maintaining tissue homeostasis and epithelial integrity. However, little is known about the ...
Persistent microbial translocation and immune activation in HIV-1–infected South Africans receiving combination antiretroviral therapy

Cassol, Edana; Malfeld, Susan; Mahasha, Phetole; Van der Merwe, Schalk Willem; Cassol, Sharon; Seebregts, Christopher J.; Alfano, Massimo; Poli, Guido; Rossouw, Theresa M. (University of Chicago Press, 2010-07)

BACKROUND: Microbial translocation contributes to immune activation and disease progression during chronic human immunodeficiency virus type 1 (HIV-1) infection. However, its role in the African AIDS epidemic remains c ...

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