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Browsing Immunology by Author "Newton, Claire L."
Now showing items 1-8 of 8
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Examining the effects of sodium ions on the binding of antagonists to dopamine D2 and D3 receptors Newton, Claire L.; Wood, Martin D.; Strange, Philip G. (Public Library of Science, 2016-07-05)Many G protein-coupled receptors have been shown to be sensitive to the presence of sodium ions (Na+). Using radioligand competition binding assays, we have examined and compared the effects of sodium ions on the binding ...
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Ludwig, Mike; Newton, Claire L. (Wiley, 2024)Robert (Bob) Millar will retire in 2024, after a long and distinguished career in neuroendocrinology. Claire and I have been working with Bob for some years and took on the task of organising a Festschrift to celebrate his ...
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Sperduti, Samantha; Limoncella, Silvia; Lazzaretti, Clara; Paradiso, Elia; Riccetti, Laura; Turchi, Sara; Ferrigno, Ilaria; Bertacchini, Jessika; Palumbo, Carla; Potì, Francesco; Longobardi, Salvatore; Millar, Robert P.; Simoni, Manuela; Newton, Claire L.; Casarini, Livio (MDPI Publishing, 2019-11-07)Commercial gonadotropin-releasing hormone (GnRH) antagonists di er by 1–2 amino acids and are used to inhibit gonadotropin production during assisted reproduction technologies (ART). In this study, potencies of three ...
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Azubuike, Udochi Felicia; Newton, Claire L.; Van den Bout, Iman (MDPI, 2022-08-06)Kisspeptin is an anti-metastatic mediator in many cancer types, acting through its receptor, KISS1R. However, controversy remains regarding its role in breast cancer since both pro- and antimetastatic roles have been ...
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Newton, Claire L.; Anderson, Ross Calley (Springer, 2018)The gonadotropin receptors (luteinising hormone receptor; LHR and follicle-stimulating hormone receptor; FSHR) are G protein-coupled receptors (GPCRs) that play an important role in the endocrine control of reproduction. ...
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Hanyroup, Sharika; Anderson, Ross Calley; Nataraja, Selvaraj; Yu, Henry N.; Millar, Robert P.; Newton, Claire L. (Oxford University Press, 2021-12)Mutations in G protein-coupled receptors (GPCRs) underlie numerous diseases. Many cause receptor misfolding and failure to reach the cell surface. Pharmacological chaperones are cell-permeant small molecules that engage ...
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Anderson, Ross Calley; Newton, Claire L.; Millar, Robert P. (Frontiers Media, 2019-01-23)The follicle-stimulating hormone receptor (FSHR) has been targeted therapeutically for decades, due to its pivotal role in reproduction. To date, only purified and recombinant/biosimilar FSH have been used to target FSHR ...
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Suthiram, Janine; Pieters, Ane; Moosa, Zulfiah Mohamed; Zeevaart, Jan Rijn; Sathekge, Mike Machaba; Ebenhan, Thomas; Anderson, Ross Calley; Newton, Claire L. (MDPI, 2023-01)Please read abstract in article.
Now showing items 1-8 of 8