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Browsing Immunology by Author "Choi, Jennifer"
Now showing items 1-6 of 6
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Blidner, Ada Gabriela; Choi, Jennifer; Cooksley, Tim; Dougan, Michael; Glezerman, Ilya; Ginex, Pamela; Girotra, Monica; Gupta, Dipti; Johnson, Douglas; Shannon, Vickie R.; Suarez-Almazor, Maria; Rapoport, Bernardo Leon; Anderson, Ronald (Springer, 2020-12)Despite the success and ongoing promise of monoclonal antibody–targeted immune checkpoint inhibitor immunotherapy of advanced malignancies, in particular, antibodies directed against CTLA-4 and PD-1/PD-L1, the development ...
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Cooksley, Tim; Girotra, Monica; Ginex, Pamela; Gordon, Ruth Ann; Anderson, Ronald; Blidner, Ada Gabriela; Choi, Jennifer; Dougan, Michael; Glezerman, Ilya; Gupta, Dipti; Johnson, Douglas; Shannon, Vickie R.; Suarez-Almazor, Maria; Rapoport, Bernardo Leon (Springer, 2020-12)Immune checkpoint inhibitors (ICIs) have emerged as the newest pillar of cancer treatment, transforming outcomes in melanoma and showing benefit in a range of malignancies. Immune-mediated toxicities, stemming from increased ...
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Suarez-Almazor, Maria; Pundole, Xerxes; Abdel-Wahab, Noha; Johnson, Douglas; Gupta, Dipti; Glezerman, Ilya; Cooksley, Tim; Anderson, Ronald; Blidner, Ada Gabriela; Choi, Jennifer; Dougan, Michael; Ginex, Pamela; Girotra, Monica; Shannon, Vickie R.; Rapoport, Bernardo Leon (Springer, 2020-12)Immune checkpoint inhibitors (ICIs) have emerged as the newest pillar of cancer treatment. Immune-mediated toxicities, stemming from increased activity within the T cell lineage, range from asymptomatic or mild complications ...
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Shannon, Vickie R.; Anderson, Ronald; Blidner, Ada Gabriela; Choi, Jennifer; Cooksley, Tim; Dougan, Michael; Glezerman, Ilya; Ginex, Pamela; Girotra, Monica; Gupta, Dipti; Johnson, Douglas; Suarez-Almazor, Maria; Rapoport, Bernardo Leon (Springer, 2020-12)The immune checkpoints associated with the CTLA-4 and PD-1 pathways are critical modulators of immune activation. These pathways dampen the immune response by providing brakes on activated T cells, thereby ensuring more ...
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Choi, Jennifer; Anderson, Ronald; Blidner, Ada Gabriela; Cooksley, Tim; Dougan, Michael; Glezerman, Ilya; Ginex, Pamela; Girotra, Monica; Gupta, Dipti; Johnson, Douglas; Shannon, Vickie R.; Suarez-Almazor, Maria; Rapoport, Bernardo Leon; Lacouture, Mario E. (Springer, 2020-12)Immune checkpoint inhibitors (ICIs) frequently result in cutaneous immune-related adverse events (IrAEs). Although the majority of these events are mild-to-moderate in severity, up to 5% are severe, which may lead to ...
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Dougan, Michael; Blidner, Ada Gabriela; Choi, Jennifer; Cooksley, Tim; Glezerman, Ilya; Ginex, Pamela; Girotra, Monica; Gupta, Dipti; Johnson, Douglas; Shannon, Vickie R.; Suarez-Almazor, Maria; Anderson, Ronald; Rapoport, Bernardo Leon (Springer, 2020-12)Immune-related adverse events (IrAEs) affecting the gastrointestinal (GI) tract and liver are among the most frequent and most severe inflammatory toxicities from contemporary immunotherapy. Inflammation of the colon and ...
Now showing items 1-6 of 6