Browsing Research Articles (Genetics) by Title

Browsing Research Articles (Genetics) by Title

Sort by: Order: Results:

  • Repeat-induced point mutations drive divergence between Fusarium circinatum and its close relatives 
    Van Wyk, Stephanie; Wingfield, Brenda D.; De Vos, Lieschen; Van der Merwe, Nicolaas Albertus (Albie); Santana, Quentin C.; Steenkamp, Emma Theodora (MDPI, 2019-12)
    The Repeat-Induced Point (RIP) mutation pathway is a fungal-specific genome defense mechanism that counteracts the deleterious effects of transposable elements. This pathway permanently mutates its target sequences by ...
  • Reproducible microbial community dynamics of two drinking water systems treating similar source waters 
    Potgieter, Sarah; Dai, Zihan; Havenga, Minette; Vosloo, Solize; Sigudu, Makhosazana; Pinto, Ameet; Venter, S.N. (Stephanus Nicolaas) (American Chemical Society, 2021-06)
    Understanding whether the spatiotemporal dynamics of the drinking water microbiome are reproducible in full-scale drinking water systems is an important step in devising engineering strategies for effectively managing and ...
  • Reproductive biology of Withania ashwagandha sp. novo (Solanaceae) 
    Mir, Bilal Ahmad; Koul, Sushma; Soodan, Amarjit Singh (Elsevier, 2013-02)
    Withania ashwagandha Kaul (Solanaceae) is an annual plant species of immense medicinal importance. It is a repository of a large number of pharmacologically active secondary metabolites known as withanolides. Evidence ...
  • Research in COVID-19 times : the way forward 
    Pepper, Michael Sean; Burton, Stephanie G. (Health and Medical Publishing Group, 2020-08)
    The COVID-19 pandemic has had a major impact on research at universities. Universities around the world, including in South Africa, have been or are still closed as part of national lockdown strategies. Students have not ...
  • A reservoir of ‘historical’ antibiotic resistance genes in remote pristine Antarctic soils 
    Van Goethem, Marc W.; Pierneef, Rian Ewald; Bezuidt, Keoagile Ignatius Oliver; Van de Peer, Yves; Cowan, Don A.; Makhalanyane, Thulani Peter (BioMed Central, 2018-02-23)
    BACKGROUND : Soil bacteria naturally produce antibiotics as a competitive mechanism, with a concomitant evolution, and exchange by horizontal gene transfer, of a range of antibiotic resistance mechanisms. Surveys of ...
  • Residual effects caused by a past mycovirus Infection in Fusarium circinatum 
    Zamora-Ballesteros, Cristina; Wingfield, Brenda D.; Wingfield, Michael J.; Martin-Garcia, Jorge; Diez, Julio J. (MDPI, 2021-01)
    Mycoviruses are known to be difficult to cure in fungi but their spontaneous loss occurs commonly. The unexpected disappearance of mycoviruses can be explained by diverse reasons, from methodological procedures to ...
  • Resistance sniffer : an online tool for prediction of drug resistance patterns of Mycobacterium tuberculosis isolates using next generation sequencing data 
    Muzondiwa, Dillon; Mutshembele, Awelani; Pierneef, Rian Ewald; Reva, Oleg N. (Elsevier, 2020-02)
    The effective control of multidrug resistant tuberculosis (MDR-TB) relies upon the timely diagnosis and correct treatment of all tuberculosis cases. Whole genome sequencing (WGS) has great potential as a method for ...
  • Reverse transcription recombinase polymerase amplification assay for rapid detection of canine associated rabies virus in Africa 
    Coertse, Jessica; Weyer, Jacqueline; Nel, Louis Hendrik; Markotter, Wanda (Public Library of Science, 2019-07)
    Rabies is a neglected disease mostly affecting the developing world. Accurate and reliable diagnostic and surveillance data forms the foundation for the formulation and monitoring of control strategies. Although various ...
  • A review of Pinaceae resistance mechanisms against needle and shoot pathogens with a focus on the Dothistroma-Pinus interaction 
    Fraser, S.; Martín-García, J.; Perry, A.; Kabir, M.S.; Owen, T.; Solla, A.; Brown, A.V.; Bulman, L.S.; Barnes, Irene; Hale, M.D.; Vasconcelos, M.W.; Lewis, K.J.; Doğmusı-Lehtijarvi, H.T.; Markovskaja, S.; Woodward, S.; Bradshaw, R.E. (Wiley, 2016-10)
    Dothistroma needle blight (DNB), caused by Dothistroma septosporum and Dothistroma pini, is a highly damaging disease of pine. DNB was originally considered a problem on exotic Pinus radiata plantations in the Southern ...
  • Revisiting ancestral polyploidy in plants 
    Ruprecht, Colin; Lohaus, Rolf; Vanneste, Kevin; Mutwil, Marek; Nikoloski, Zoran; Van de Peer, Yves; Persson, Staffan (American Association for the Advancement of Science, 2017-07-05)
    Whole-genome duplications (WGDs) or polyploidy events have been studied extensively in plants. In a now widely cited paper, Jiao et al. presented evidence for two ancient, ancestral plant WGDs predating the origin of ...
  • Revisiting the phenomenon of cellulase action : not all endo-and exo-cellulase interactions are synergistic 
    Thoresen, Mariska; Malgas, Samkelo; Mafa, Mpho Stephen; Pletschke, Brett Ivan (MDPI, 2021-01)
    The conventional endo–exo synergism model has extensively been supported in literature, which is based on the perception that endoglucanases (EGs) expose or create accessible sites on the cellulose chain to facilitate ...
  • Rhizosheath microbial community assembly of sympatric desert speargrasses is independent of the plant host 
    Marasco, Ramona; Mosqueira, María J.; Fusi, Marco; Ramond, Jean-Baptiste; Merlino, Giuseppe; Maggs-Kölling, Gillian; Booth, Jenny M.; Cowan, Don A.; Daffonchio, Daniele (BMC, 2018-12)
    Background The rhizosheath-root system is an adaptive trait of sandy-desert speargrasses in response to unfavourable moisture and nutritional conditions. Under the deserts’ polyextreme conditions, plants interact with ...
  • The RIPper, a web-based tool for genome-wide quantification of repeat-induced point (RIP) mutations 
    Van Wyk, Stephanie; Harrison, Christopher H.; Wingfield, Brenda D.; De Vos, Lieschen; Van der Merwe, Nicolaas Albertus (Albie); Steenkamp, Emma Theodora (PeerJ, 2019-08)
    BACKGROUND. The RIPper (http://theripper.hawk.rocks) is a set of web-based tools designed for analyses of Repeat-Induced Point (RIP) mutations in the genome sequences of Ascomycota. The RIP pathway is a fungal genome ...
  • The road to resistance in forest trees 
    Naidoo, Sanushka; Slippers, Bernard; Plett, Jonathan M.; Coles, Donovin; Oates, Caryn Nicole (Frontiers Media, 2019-03-29)
    In recent years, forests have been exposed to an unprecedented rise in pests and pathogens. This, coupled with the added challenge of climate change, renders forest plantation stock vulnerable to attack and severely limits ...
  • A roadmap for Antarctic and Southern Ocean science for the next two decades and beyond 
    Kennicutt II, M.C.; Chown, Steven Loudon; Cassano, J.J.; Liggett, D.; Peck, L.S.; Massom, R.; Rintoul, S.R.; Storey, J.; Vaughan, D.G.; Wilson, T.J.; Allison, I.; Ayton, J.; Badhe, R.; Baeseman, J.; Barrett, P.J.; Bell, R.E.; Bertler, N.; Bo, S.; Brandt, A.; Bromwich, D.; Cary, S.C.; Clark, M.S.; Convey, P.; Costa, E.S.; Cowan, Don A.; Deconto, R.; Dunbar, R.; Elfring, C.; Escutia, C.; Francis, J.; Fricker, H.A.; Fukuchi, M.; Gilbert, N.; Gutt, J.; Havermans, C.; Hik, D.; Hosie, G.; Jones, G.; Kim, Y. D.; Le Maho, Y.; Lee, S.H.; Leppe, M.; Leitchenkov, G.; Li, X.; Lipenkov, V.; Lochte, K.; López-Martínez, J.; Lüdecke, C.; Lyons, W.; Marenssi, S.; Miller, H.; Morozova, P.; Naish, T.; Nayak, S.; Ravindra, R.; Retamales, J.; Ricci, C.A.; Rogan-Finnemore, M.; Ropert-Coudert, Y.; Samah, A.A.; Sanson, L.; Scambos, T.; Schloss, I.R.; Shiraishi, K.; Siegert, M.J.; Simões, J.C.; Storey, B.; Sparrow, M.D.; Wall, D.H.; Walsh, J.C.; Wilson, G.; Winther, J.G.; Xavier, J.C.; Yang, H.; Sutherland, W.J. (Cambridge University Press, 2015-02)
    Antarctic and Southern Ocean science is vital to understanding natural variability, the processes that govern global change and the role of humans in the Earth and climate system. The potential for new knowledge to be ...
  • Roadmap for naming uncultivated Archaea and Bacteria 
    Murray, Alison E.; Freudenstein, John; Gribaldo, Simonetta; Hatzenpichler, Roland; Hugenholtz, Philip; Kampfer, Peter; Konstantinidis, Konstantinos T.; Lane, Christopher E.; Papke, R. Thane; Parks, Donovan H.; Rossello-Mora, Ramon; Stott, Matthew B.; Sutcliffe, Iain C.; Thrash, J. Cameron; Venter, S.N. (Stephanus Nicolaas); Whitman, William B.; Acinas, Silvia G.; Amann, Rudolf I.; Anantharaman, Karthik; Armengaud, Jean; Baker, Brett J.; Barco, Roman A.; Bode, Helge B.; Boyd, Eric S.; Brady, Carrie Louise; Carini, Paul; Chain, Patrick S.G.; Colman, Daniel R.; DeAngelis, Kristen M.; De los Rios, Maria Asuncion; Estrada-de los Santos, Paulina; Dunlap, Christopher A.; Eisen, Jonathan A.; Emerson, David; Ettema, Thijs J.G.; Eveillard, Damien; Girguis, Peter R.; Hentschel, Ute; Hollibaugh, James T.; Hug, Laura A.; Inskeep, William P.; Ivanova, Elena P.; Klenk, Hans-Peter; Li, Wen-Jun; Lloyd, Karen G.; Loffler, Frank E.; Makhalanyane, Thulani Peter; Moser, Duane P.; Nunoura, Takuro; Palmer, Marike; Parro, Victor; Pedrós-Alio, Carlos; Probst, Alexander J.; Smits, Theo H.M.; Steen, Andrew D.; Steenkamp, Emma Theodora; Spang, Anja; Stewart, Frank J.; Tiedje, James M.; Vandamme, Peter; Wagner, Michael; Wang, Feng-Ping; Yarza, Pablo; Hedlund, Brian P.; Reysenbach, Anna-Louise (Nature Research, 2020-06-08)
    The assembly of single-amplified genomes (SAGs) and metagenome-assembled genomes (MAGs) has led to a surge in genome-based discoveries of members affiliated with Archaea and Bacteria, bringing with it a need to develop ...
  • The role of aDNA in understanding the coevolutionary patterns of human sexually transmitted infections 
    Pimenoff, Ville N.; Houldcroft, Charlotte J.; Rifkin, Riaan F.; Underdown, Simon (MDPI, 2018-07)
    Analysis of pathogen genome data sequenced from clinical and historical samples has made it possible to perform phylogenetic analyses of sexually transmitted infections on a global scale, and to estimate the diversity, ...
  • Role of plants in anticancer drug discovery 
    Khazir, Jabeena; Mir, Bilal Ahmad; Pilcher, Lynne A.; Riley, Darren L. (Elsevier, 2014-02)
    Cancer is one of the major causes of death and the number of new cases, as well as the number of individuals living with cancer, is expanding continuously. Worldwide the alarming rise in mortality rate due to cancer has ...
  • The role of reactive oxygen species in adipogenic differentiation 
    De Villiers, Danielle; Potgieter, Marnie; Ambele, Melvin Anyasi; Adam, Ladislaus; Durandt, Chrisna; Pepper, Michael Sean (Springer, 2017-11)
    Interest in reactive oxygen species and adipocyte differentiation/adipose tissue function is steadily increasing. This is due in part to a search for alternative avenues for combating obesity, which results from the excess ...
  • Roles of plant volatiles in defence against microbial pathogens and microbial exploitation of volatiles 
    Hammerbacher, Almuth; Coutinho, Teresa A.; Gershenzon, Jonathan (Wiley, 2019-10)
    Plants emit a large variety of volatile organic compounds during infection by pathogenic microbes, including terpenes, aromatics, nitrogen‐containing compounds, and fatty acid derivatives, as well as the volatile plant ...