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Browsing Genetics by Author "Niemand, Jandeli"
Now showing items 1-6 of 6
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Moyo, Phanankosi; Kunyane, Phaladi; Selepe, Mamoalosi A.; Eloff, Jacobus Nicolaas; Niemand, Jandeli; Louw, Abraham Izak; Maharaj, Vinesh J.; Birkholtz, Lyn-Marie (BioMed Central, 2019-03-08)BACKGROUND : Optimal adoption of the malaria transmission-blocking strategy is currently limited by lack of safe and efficacious drugs. This has sparked the exploration of different sources of drugs in search of ...
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Niemand, Jandeli; Van Biljon, Riette Andele; Van der Watt, Mariette Elizabeth; Van Heerden, Ashleigh; Reader, Janette; Van Wyk, Roelof Daniel Jacobus; Orchard, Lindsey M.; Chibale, Kelly; Llinas, Manuel; Birkholtz, Lyn-Marie (American Chemical Society, 2021-09)Please read abstract in the article.
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Van Biljon, Riette Andele; Van Wyk, Roelof Daniel Jacobus; Painter, Heather J.; Orchard, Lindsey; Reader, Janette; Niemand, Jandeli; Llinas, Manuel; Birkholtz, Lyn-Marie (BioMed Central, 2019-12)BACKGROUND : Malaria pathogenesis relies on sexual gametocyte forms of the malaria parasite to be transmitted between the infected human and the mosquito host but the molecular mechanisms controlling gametocytogenesis ...
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Morahan, Belinda J.; Abrie, Clarissa; Al-Hasani, Keith; Batty, Mitchell B.; Corey, Victoria; Cowell, Anne N.; Niemand, Jandeli; Winzeler, Elizabeth A.; Birkholtz, Lyn-Marie; Doerig, Christian; Garcia-Bustos, Jose F. (Nature Research, 2020-11)Mitosis has been validated by numerous anti-cancer drugs as being a druggable process, and selective inhibition of parasite proliferation provides an obvious opportunity for therapeutic intervention against malaria. ...
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Van Biljon, Riette Andele; Niemand, Jandeli; Clark, Katherine; Verlinden, Bianca K.; Abrie, Clarissa; Von Gruning, Hilde; Smidt, Werner; Smit, Annel; Reader, Janette; Painter, Heather; Llinas, Manuel; Doerig, Christian; Birkholtz, Lyn-Marie (Nature Publishing Group, 2018-11-08)The life cycle of the malaria parasite Plasmodium falciparum is tightly regulated, oscillating between stages of intense proliferation and quiescence. Cyclic 48-hour asexual replication of Plasmodium is markedly different ...
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Rossouw, Ingrid; Maritz-Olivier, Christine; Niemand, Jandeli; Van Biljon, Riette Andele; Smit, Annel; Olivier, Nicholas Abraham; Birkholtz, Lyn-Marie; Small, Pamela L.C. (Public Library of Science, 2015-05-08)Human babesiosis, especially caused by the cattle derived Babesia divergens parasite, is on the increase, resulting in renewed attentiveness to this potentially life threatening emerging zoonotic disease. The molecular ...
Now showing items 1-6 of 6