Browsing Genetics by Title

Browsing Genetics by Title

Sort by: Order: Results:

  • Inheritance of deleterious mutations at both BRCA1 and BRCA2 in an international sample of 32,295 women 
    Rebbeck, Timothy R.; Friebel, Tara M.; Mitra, Nandita; Wan, Fei; Chen, Stephanie; Andrulis, Irene L.; Apostolou, Paraskevi; Arnold, Norbert; Arun, Banu K.; Barrowdale, Daniel; Benitez, Javier; Berger, Raanan; Berthet, Pascaline; Borg, Ake; Buys, Saundra S.; Carter, Jonathan; Chiquette, Jocelyne; Claes, Kathleen B.M.; Couch, Fergus J.; Cybulski, Cezary; Daly, Mary B.; De la Hoya, Miguel; Diez, Orland; Domchek, Susan M.; Nathanson, Katherine L.; Durda, Katarzyna; Ellis, Steve; EMBRACE; Evans, D. Gareth; Foretova, Lenka; Friedman, Eitan; Frost, Debra; Ganz, Patricia A.; Garber, Judy; Glendon, Gord; Godwin, Andrew K.; Greene, Mark H.; Gronwald, Jacek; Hahnen, Eric; Hallberg, Emily; Hamann, Ute; Hansen, Thomas V.O.; HEBON; Imyanitov, Evgeny N.; Isaacs, Claudine; Jakubowska, Anna; Janavicius, Ramunas; Jaworska-Bieniek, Katarzyna; John, Esther M.; Karlan, Beth Y.; Kaufman, Bella; KConFab investigators; Kwong, Ava; Laitman, Yael; Lasset, Christine; Lazaro, Conxi; Lester, Jenny; Loman, Niklas; Lubinski, Jan; Manoukian, Siranoush; Mitchell, Gillian; Montagna, Marco; Neuhausen, Susan L.; Nevanlinna, Heli; Niederacher, Dieter; Nussbaum, Robert L.; Offit, Kenneth; Olah, Edith; Olopade, Olufunmilayo I.; Park, Sue Kyung; Piedmonte, Marion; Radice, Paolo; Rappaport-Fuerhauser, Christine; Rookus, Matti A.; Seynaeve, Caroline; Simard, Jacques; Singer, Christian F.; Soucy, Penny; Southey, Melissa; Stoppa-Lyonnet, Dominique; Sukiennicki, Grzegorz; Szabo, Csilla I.; Tancredi, Mariella; Teixeira, Manuel R.; Teo, Soo-Hwang; Terry, Mary Beth; Thomassen, Mads; Tihomirova, Laima; Tischkowitz, Marc; Toland, Amanda Ewart; Toloczko-Grabarek, Aleksandra; Tung, Nadine; Jansen van Rensburg, Elizabeth; Villano, Danylo; Wang-Gohrke, Shan; Wappenschmidt, Barbara; Weitzel, Jeffrey N.; Zidan, Jamal; Zorn, Kristin K.; McGuffog, Lesley; Easton, Douglas; Chenevix-Trench, Georgia; Antoniou, Antonis C.; Ramus, Susan J. (BioMed Central, 2016-11-11)
    BACKGROUND : Most BRCA1 or BRCA2 mutation carriers have inherited a single (heterozygous) mutation. Transheterozygotes (TH) who have inherited deleterious mutations in both BRCA1 and BRCA2 are rare, and the consequences ...
  • Inheritance of phenotypic traits in the progeny of a Ceratocystis interspecific cross 
    Fourie, Arista; Wingfield, Michael J.; Wingfield, Brenda D.; Van der Nest, Magrieta Aletta; Loots, Mattheus Theodor; Barnes, Irene (Elsevier, 2018-07)
    Ceratocystis fimbriata is a fungal plant pathogen that causes black rot on Ipomoea batatas. Based on inoculation studies on numerous tree species, the pathogen is known to be host specific. The closely related species, ...
  • Inherited predisposition to breast/ovarian cancer : the frequency and nature of BRCA1 gene mutations in South African families 
    Yawitch, Tali Michelle (University of Pretoria, 2005-01-09)
    Breast cancer is the most common cancer in South African women. Approximately 5¬10% of all breast cancer cases are due to an inherited predisposition, resulting from mutations in tumour suppressor genes. The BRCA1 gene on ...
  • Insect associates of Ceratocystis albifundus and patterns of association in a native savanna ecosystem in South Africa 
    Heath, R.N. (Ronald Natale); Wingfield, Michael J.; Van Wyk, Marelize; Roux, Jolanda (Entomological Society of America, 2009)
    Species of Ceratocystis Ellis and Halstead s.l. include important plant pathogens such as C. albifundus Morris, De Beer, and M. J. Wingfield that causes a serious wilt disease of non-native, plantation-grown Acacia mearnsii ...
  • Insect gallers and their plant hosts : from omics data to systems biology 
    Oates, Caryn Nicole; Denby, Katherine J.; Myburg, Alexander Andrew; Slippers, Bernard; Naidoo, Sanushka (MDPI Publishing, 2016)
    Gall-inducing insects are capable of exerting a high level of control over their hosts’ cellular machinery to the extent that the plant’s development, metabolism, chemistry, and physiology are all altered in favour of ...
  • Insights into the evolution of multicellularity from the sea lettuce genome 
    De Clerck, Olivier; Kao, Shu-Min; Bogaert, Kenny A.; Blomme, Jonas; Foflonker, Fatima; Kwantes, Michiel; Vancaester, Emmelien; Vanderstraeten, Lisa; Aydogdu, Eylem; Boesger, Jens; Califano, Gianmaria; Charrier, Benedicte; Clewes, Rachel; Del Cortona, Andrea; D’Hondt, Sofie; Fernandez-Pozo, Noe; Gachon, Claire M.; Hanikenne, Marc; Lattermann, Linda; Leliaert, Frederik; Liu, Xiaojie; Maggs, Christine A.; Popper, Zoë A.; Raven, John A.; Van Bel, Michiel; Wilhelmsson, Per K.I.; Bhattacharya, Debashish; Coates, Juliet C.; Rensing, Stefan A.; Van der Straeten, Dominique; Vardi, Assaf; Sterck, Lieven; Vandepoele, Klaas; Van de Peer, Yves; Wichard, Thomas; Bothwell, John H. (Elsevier (Cell Press), 2018-09)
    We report here the 98.5 Mbp haploid genome (12,924 protein coding genes) of Ulva mutabilis, a ubiquitous and iconic representative of the Ulvophyceae or green seaweeds. Ulva’s rapid and abundant growth makes it a key ...
  • Insights into the mechanisms implicated in Pinus pinaster resistance to pinewood nematode 
    Modesto, Ines; Sterck, Lieven; Arbona, Vicent; Gomez-Cadenas, Aurelio; Carrasquinho, Isabel; Van de Peer, Yves; Miguel, Celia M. (Frontiers Media, 2021-06-10)
    Pine wilt disease (PWD), caused by the plant–parasitic nematode Bursaphelenchus xylophilus, has become a severe environmental problem in the Iberian Peninsula with devastating effects in Pinus pinaster forests. Despite ...
  • Inspiratory muscle training in severe spinal muscular atrophy : a case report 
    Human, Anri; Honey, Engela M.; Morrow, Brenda (Mark Allen Healthcare Limited, 2019-05)
    BACKGROUND/AIMS : Inspiratory muscle training aims to preserve or improve respiratory muscle strength in children with neuromuscular diseases in order to prevent or minimise pulmonary morbidity. The aim of this study was ...
  • Integration of genomic and proteomic analyses in the classification of the Siphoviridae family 
    Adriaenssens, Evelien M.; Edwards, Robert P.; Nash, John H.E.; Mahadevan, Padmanabhan; Seto, Donald; Ackermann, Hans-Wolfgang; Lavigne, Rob; Kropinski, Andrew M. (Elsevier, 2015-03)
    Using a variety of genomic (BLASTN, ClustalW) and proteomic (Phage Proteomic Tree, CoreGenes) tools we have tackled the taxonomic status of members of the largest bacteriophage family, the Siphoviridae. In all over 400 ...
  • An integrative approach to understanding pyrethroid resistance in Rhipicephalus microplus and R. decoloratus ticks 
    Van Wyk, Roelof Daniel Jacobus; Baron, Samantha; Maritz-Olivier, Christine (Elsevier, 2016-06)
    Rhipicephalus microplus and Rhipicephalus decoloratus species occur in regions with savannah and temperate climates, typically in grassland and wooded areas used as cattle pasture. Both species are associated with the ...
  • Interaction of nonstructural protein NS3 of African horsesickness virus with viral and cellular proteins 
    Beyleveld, Mia (University of Pretoria, 2007)
    African horsesickness virus (AHSV) is a dsRNA virus that belongs to the Orbivirus genus within the Reoviridae family. Each of the ten viral dsRNA segments encodes one virus-specific protein. During its life cycle AHSV ...
  • Interaction specificity between leaf-cutting ants and vertically transmitted Pseudonocardia bacteria 
    Andersen, Sandra B.; Yek, Sze Huei; Nash, David R.; Boomsma, Jacobus J. (BioMed Central, 2015)
    BACKGROUND : The obligate mutualism between fungus-growing ants and microbial symbionts offers excellent opportunities to study the specificity and stability of multi-species interactions. In addition to cultivating ...
  • Interactions between hymenopteran species associated with gall‐forming wasps : the Leptocybe invasa community as a case study 
    Gevers, Caitlin R.; Dittrich-Schroder, Gudrun; Slippers, Bernard; Hurley, Brett Phillip (Wiley, 2021-05)
    1. Leptocybe invasa is native to Australia and induces galls on various species of Eucalyptus. Two genetically distinct lineages of this wasp have been detected outside its native range, namely, Leptocybe Lineage A and ...
  • Internalin AB-expressing recombinant Lactobacillus casei protects Caco-2 cells from Listeria monocytogenes-induced damages under simulated intestinal conditions 
    Bhunia, Arun K.; Thantsha, Mapitsi Silvester (Public Library of Science, 2019-07-29)
    Please read abstract in the article.
  • Internet access constrains science development and training at South African universities 
    Slippers, Bernard; Majozi, Thokozani; Nelwamondo, Fulufhelo V.; Steenkamp, Christine M.; Van Heerden, Esta; Wright, Caradee Yael (Academy of Science of South Africa, 2011)
    As a group of young scientists whose future careers depend increasingly on access to Internet resources, we are extremely concerned by the apparent lack of understanding of the stranglehold that current approaches to ...
  • The intracellular bacterium Wolbachia uses parasitoid wasps as phoretic vectors for efficient horizontal transmission 
    Ahmed, Muhammad Zaheerudin; Li, Shao-Jian; Xue, Xia; Yin, Xiang-Jie; Ren, Shun-Xiang; Jiggins, Francis M.; Greeff, Jaco M. (Jacobus Maree); Qiu, Bao-Li (Public Library of Science, 2015-02)
    Facultative bacterial endosymbionts are associated with many arthropods and are primarily transmitted vertically from mother to offspring. However, phylogenetic affiliations suggest that horizontal transmission must also ...
  • Intraspecific genetic variation in the percoid teleosts Argyrosomus japonicus (Temminck&Schlegel, 1843) and Pomadasys commersonnii (Lacepède, 1801), as inferred from the mitochondrial control region 
    Klopper, Arrie Willem (University of Pretoria, 2005)
    Dusky kob, Argyrosomus japonicus and spotted grunter, Pomadasys commersonnii occur off South Africa’s southern and eastern seaboard. They are the preferred target species for both shore and estuarine anglers. In order to ...
  • Invasion history and management of Eucalyptus snout beetles in the Gonipterus scutellatus species complex 
    Schroder, Michelle L.; Slippers, Bernard; Wingfield, Michael J.; Hurley, Brett Phillip (Springer, 2020-01)
    Gonipterus scutellatus (Coleoptera: Curculionidae), once thought to be a single species, is now known to reside in a complex of at least eight cryptic species. Two of these species (G. platensis and G. pulverulentus) and ...
  • Invasive gall-forming wasps that threaten non-native plantation-grown Eucalyptus : diversity and invasion patterns 
    Dittrich-Schroder, Gudrun; Hurley, Brett Phillip; Wingfield, Michael J.; Nahrung, Helen F.; Slippers, Bernard (Wiley, 2020-11)
    Gall‐forming hymenopterans of Eucalyptus species are highly successful invaders causing significant damage in non‐native plantation forests. To date, at least 16 of these species have been recorded as invasive eucalypt ...
  • Investigating the effects of RBBP6 gene expression on telomerase activity in cervical cancer 
    Mosweu, Mpho (University of Pretoria, 2020)
    Cancer remains a major health problem. It is ranked the second most common cause of death to cardiovascular diseases worldwide, with about 9.6 million deaths annually. This burden is greatly carried by developing countries, ...