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Browsing Research Articles (Physiology) by Subject "Lysotracker staining"

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A novel 2-methoxyestradiol analogue is responsible for vesicle disruption and lysosome aggregation in breast cancer cells

Nkandeu, D.S. (Danielle Sandra); Van den Bout, Jan Iman; Cronjé, Marianne J.; Van Papendorp, D.H. (Dirk Hermanus), 1949-; Joubert, Anna Margaretha (Karger Publishers, 2018)

BACKGROUND : 2-Methoxyestradiol (2ME2) is an endogenous metabolite of 17-β-estradiol with anti-proliferative and anti-angiogenic properties. Due to 2ME2’s rapid metabolism and low oral bioavailability in in vivo settings, ...

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