Browsing Research Articles (Physiology) by Subject "L‐Kynurenine"

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An in vitro investigation of l-kynurenine, quinolinic acid, and kynurenic acid on B16 F10 melanoma cell cytotoxicity and morphology

Basson, Charlise; Serem, June Cheptoo; Hlophe, Yvette Nkondo; Bipath, Priyesh (Wiley, 2023-10)

The metastatic behavior of melanoma has accentuated the need for specific therapy targets. Compounds, namely L‐kynurenine (L‐kyn), quinolinic acid (Quin), and kynurenic acid (KA) previously displayed antiproliferative ...
The involvement of a chemokine receptor antagonist CTCE-9908 and kynurenine metabolites in cancer development

Nkandeu, D.S. (Danielle Sandra); Basson, Charlise; Joubert, Anna Margaretha; Serem, June Cheptoo; Bipath, Priyesh; Nyakudya, Trevor Tapiwa; Hlophe, Yvette Nkondo (Wiley, 2022-08)

Cancer is the second leading cause of mortality worldwide. Skin cancer is the most common cancer in South Africa with nearly 20,000 reported cases every year and 700 deaths. If diagnosed early, the 5‐year survival rate ...

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