Antimitotic compounds are still one of the most widely used chemotherapeutic anticancer drugs in the clinic today. Given
their effectiveness against cancer it is beneficial to continue enhancing these drugs. One way is ...
BACKGROUND : 2-Ethyl-3-O-sulphamoyl-estra-1,3,5(10)16-tetraene (ESE-16) is a unique, in silico-designed compound
with possible anticancer properties, which were identified in our laboratory. This compound is capable ...
Cancer is the second leading cause of death in South Africa. The
critical role that microtubules play in cell division makes them an ideal target
for the development of chemotherapeutic drugs that prevent the
hyperproliferation ...
The aim of this study was to characterize the in vitro action of 2-ethyl-3-O-sulphamoyl-estra-1,3,5(10)16-tetraene (ESE-16) on
non-tumorigenic MCF-12A, tumorigenic MCF-7 and metastatic MDA-MB-231 breast cancer cells. ...
