Mathews, Edward Henry; Visagie, M.H. (Michelle Helen); Meyer, Albertus Abram; Joubert, Anna Margaretha; Mathews, George Edward(Elsevier, 2020-06)
OBJECTIVE : Although metabolic treatment of highly glycolytic cancers and metastases is becoming an important research field, the effects of such treatments are not fully quantified yet. In this article we attempt to ...
BACKGROUND : Due to their high proliferative requirements, tumorigenic cells possess altered metabolic systems
whereby cells utilize higher quantities of glutamine and glucose. These altered metabolic requirements make ...
Mathews, Edward Henry; Stander, Barend Andre; Joubert, Annie M.; Liebenberg, Leon(Elsevier, 2014-02)
OBJECTIVE : Most glucose (and glutamine)-deprivation studies of cancer cell cultures focus on total depletion, and are conducted over at least 24 h. It is difficult to extrapolate findings from such experiments to practical ...
