Joubert, Annie M.; Maritz, Christine; Joubert, Fourie(Biomedical Research Press, 2005-06)
2-Methoxyestradiol (2ME), an endogenous metabolite of 17Beta-estradiol, has been reported to play an active role in the induction of apoptosis in both proliferating endothelial and cancer cells. Since it has been indicated ...
Joubert, Annie M.; Marais, Sumari; Maritz, Christine(Centro Regional de Investigaciones Cientificas Y Tecnologicas / Universidad Nacional de Cuyo, 2009-02)
Proteins of the B-cell lymphoma 2 family are crucial for the regulation of apoptosis. B-cell
lymphoma 2-associated X is a pro-apoptotic protein, while B-cell lymphoma 2 protein opposes apoptosis. The influence of 1 μM ...
Joubert, Annie M.; Maritz, Christine; Joubert, Fourie(Biomedical Research Press, 2005-04)
Proteins of the Bcl-2 family are key regulators of apoptosis. Bax can be regarded as pro-apoptotic, whereas Bcl-2 is perceived as anti-apoptotic. It has been proposed that an increased ratio of proapoptotic Bax to ...
Joubert, Annie M.; Bianchi, Pepita; Maritz, Christine; Joubert, Fourie(Biomedical Research Press, 2006-08)
The effects of 20 μg/mL exogenous prostaglandin A2 (PGA2) were determined on Bax, Bcl-2 and proliferating cell nuclear antigen (PCNA) expression levels in MCF-7 cells. Flow cytometric analysis indicated a pronounced increase ...
