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Browsing Research Articles (Physiology) by Author "Gwangwa, Mokgadi Violet"

Now showing items 1-4 of 4

Comparison of structures and cytotoxicity of mupirocin and batumin against melanoma and several other cancer cell lines

Reva, Oleg N.; Rademan, Sunelle; Visagie, M.H. (Michelle Helen); Lebelo, M.T. (Maphuti); Gwangwa, Mokgadi Violet; Klochko, Vitalii V.; Joubert, Anna Margaretha; Lall, Namrita (Future Science, 2019)

AIM : To determine the computer-predicted anticancer activity of mupirocin and to compare its activities with those determined for another polyene antibiotic, batumin. MATERIALS AND METHODS : Molecular docking, cytotoxicity ...
Crosstalk between the Warburg effect, redox regulation and autophagy induction in tumourigenesis

Gwangwa, Mokgadi Violet; Joubert, Anna Margaretha; Visagie, M.H. (Michelle Helen) (BioMed Central, 2018-05-04)

Tumourigenic tissue uses modified metabolic signalling pathways in order to support hyperproliferation and survival. Cancer-associated aerobic glycolysis resulting in lactic acid production was described nearly 100 years ...
Effects of glutamine deprivation on oxidative stress and cell survival in breast cell lines

Gwangwa, Mokgadi Violet; Joubert, Anna Margaretha; Visagie, M.H. (Michelle Helen) (BioMed Central, 2019-03-27)

BACKGROUND : Tumourigenic cells modify metabolic pathways in order to facilitate increased proliferation and cell survival resulting in glucose- and glutamine addiction. Previous research indicated that glutamine deprivation ...
Promising anticancer activity of batumin : a natural polyene antibiotic produced by Pseudomonas batumici

Soldatkina, Maria.A.; Klochko, Vitalii V.; Zagorodnya, Svitlana D.; Rademan, Sunelle; Visagie, M.H. (Michelle Helen); Lebelo, M.T. (Maphuti); Gwangwa, Mokgadi Violet; Joubert, Anna Margaretha; Lall, Namrita; Reva, Oleg N. (Future Science, 2018-09)

AIM : To determine the computer-predicted anticancer activity of antibiotic batumin. MATERIALS AND METHODS : Cytotoxicity assays, cell morphology microscopy and cell cycle progression were studied in cancer and nontumorigenic ...

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Browsing Research Articles (Physiology) by Author "Gwangwa, Mokgadi Violet"

Browsing Research Articles (Physiology) by Author "Gwangwa, Mokgadi Violet"

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