Browsing Research Articles (Medical Microbiology) by Title

Browsing Research Articles (Medical Microbiology) by Title

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  • A phase 2 study to evaluate the safety and immunogenicity of a recombinant HIV type 1 vaccine based on adeno-associated virus 
    Vardas, Eftyxia; Kaleebu, Pontiano; Bekker, Linda-Gail; Hoosen, Anwar Ahmed; Chomba, Elwyn; Johnson, Philip R.; Anklesaria, Pervin; Birungi, Josephine; Barin, Burc; Boaz, Mark; Cox, Josephine; Lehrman, Jennifer; Stevens, Gwynn; Gilmour, Jill; Tarragona, Tony; Hayes, Peter; Lowenbein, Sarah; Kizito, Eva; Fast, Patricia; Heald, Alison E.; Schmidt, Claudia (Mary Ann Liebert, 2010)
    The recombinant vaccine, tgAAC09, based on an adeno-associated virus serotype 2 (AAV2) vector encoding HIV-1 subtype C Gag, protease, and part of reverse transcriptase, induced robust T cell and antibody responses in ...
  • Phase I, single-dose, dose-escalating study of inhaled dry powder capreomycin : a new approach to therapy of drug-resistant tuberculosis 
    Dharmadhikari, Ashwin S.; Kabadi, Mohan; Gerety, Bob; Hickey, Anthony J.; Fourie, P.B. (Petrus Bernardus); Nardell, Edward Anthony (American Society for Microbiology, 2013-06)
    Multidrug-resistant tuberculosis (MDR-TB) threatens global TB control. The lengthy treatment includes one of the injectable drugs kanamycin, amikacin, and capreomycin, usually for the first 6 months. These drugs have ...
  • Phylogenomic and epidemiological insights into two clinical Mycobacterium bovis BCG strains circulating in South Africa 
    Modipane, Lesedi; Reva, Oleg N.; Magazi, Beki T.; Antiabong, John Francis; Osei Sekyere, John; Mbelle, Nontombi Marylucy (Elsevier, 2019-10)
    BACKGROUND : Mycobacterium bovis BCG is a live, attenuated tuberculosis vaccine. While the vaccine protects infants from tuberculosis, complications including disseminated infections have been reported following ...
  • Plasmid evolution in carbapenemase‐producing Enterobacteriaceae : a review 
    Kopotsa, Katlego; Osei Sekyere, John; Mbelle, Nontombi Marylucy (Wiley, 2019-12)
    Please read abstract in the article.
  • Plasmodium ovale : a case of not-so-benign tertian malaria 
    Strydom, Kathy-Anne; Ismail, Farzanah; Frean, John (BioMed Central, 2014-03-10)
    Severe malaria is most commonly associated with Plasmodium falciparum. Plasmodium vivax is increasingly recognized as being capable of causing severe disease. In contrast, Plasmodium ovale is considered as a cause of benign ...
  • Population dynamics of Escherichia coli causing bloodstream infections over extended time periods 
    Pitout, Johann D.D. (American Society for Microbiology, 2021-12-22)
    Escherichia coli is a leading cause of community-acquired and health careassociated bloodstream infections (BSIs) worldwide. Limited information is available regarding the changes in population dynamics of human E. coli ...
  • Population pharmacokinetic drug-drug interaction pooled analysis of existing data for rifabutin and HIV PIs 
    Hennig, Stefanie; Svensson, Elin M.; Niebecker, Ronald; Fourie, P.B. (Petrus Bernardus); Weiner, Marc H.; Bonora, Stefano; Peloquin, Charles A.; Gallicano, Keith; Flexner, Charles; Pym, Alex; Vis, Peter; Olliaro, Piero L.; McIlleron, Helen; Karlsson, Mats O. (Oxford University Press, 2016-05)
    OBJECTIVES : Extensive but fragmented data from existing studies were used to describe the drug-drug interaction between rifabutin and HIV-protease inhibitors, and predict doses achieving recommended therapeutic exposure ...
  • The population structure of clinical extra-intestinal Escherichia coli in a teaching hospital from Nigeria 
    Seni, Jeremiah; Peirano, Gisele; Okon, Kenneth Okwong; Jibrin, Yusuf Bara; Mohammed, Alkali; Mshana, Stephen E.; DeVinney, Rebekah; Pitout, Johann D.D. (Elsevier, 2018-09)
    Limited information is available regarding the population structure of extra-intestinal pathogenic Escherichia coli (ExPEC) in Africa. Antimicrobial resistance profiles, sequence types (STs) and fimH types were determined ...
  • Population-based epidemiology of Escherichia coli ST1193 causing blood stream infections in a centralized Canadian region 
    Peirano, Gisele; Matsumara, Yasufumi; Nobrega, Diego; DeVinney, Rebekah; Pitout, Johann D.D. (Springer, 2023)
    Please read abstract in the article.
  • Population-based genomic surveillance of Pseudomonas aeruginosa causing bloodstream infections in a large Canadian health region 
    Peirano, Gisele; Matsumara, Yasufumi; Nobrega, Diego; Church, Deirdre; Pitout, Johann D.D. (Springer, 2024-03)
    Please read abstract in the article.
  • Population-based resistance of Mycobacterium tuberculosis isolates to pyrazinamide and fluoroquinolones : results from a multicountry surveillance project 
    Zignol, Matteo; Dean, Anna S.; Alikhanova, Natavan; Andres, Sonke; Cabibbe, Andrea Maurizio; Cirillo, Daniela Maria; Dadu, Andrei; Dreyer, Andries; Driesen, Michèle; Gilpin, Christopher; Hasan, Rumina; Hasan, Zahra; Hoffner, Sven; Husain, Ashaque; Hussain, Alamdar; Ismail, Nazir Ahmed; Kamal, Mostofa; Mansjo, Mikael; Mvusi, Lindiwe; Niemann, Stefan; Omar, Shaheed Vally; Qadeer, Ejaz; Rigouts, Leen; Ruesch-Gerdes, Sabine; Schito, Marco; Seyfaddinova, Mehriban; Skrahina, Alena; Tahseen, Sabira; Wells, William A.; Mukadi, Ya Diul; Kimerling, Michael; Floyd, Katherine; Weyer, Karin; Raviglione, Mario C. (Elsevier, 2016-10)
    BACKGROUND : Pyrazinamide and fluoroquinolones are essential antituberculosis drugs in new rifampicin-sparing regimens. However, little information about the extent of resistance to these drugs at the population level is ...
  • Population-based surveillance of Enterobacter cloacae complex causing blood stream infections in a centralized Canadian region 
    Stokes, William; Peirano, Gisele; Matsumara, Yasufumi; Nobrega, Diego; Pitout, Johann D.D. (Springer, 2022-01)
    Active population-based surveillance determined clinical factors, susceptibility patterns, incidence rates (IR), and genomics among Enterobacter cloacae complex (n = 154) causing blood stream infections in a centralized ...
  • Possible transmission of human immunodeficiency virus-1 infection from an elite controller to a patient who progressed to acquired immunodeficiency syndrome : a case report 
    Killian, Michael Scott; Vyas, Girish N.; Mehta, Rochak; Young, Karen; Ebrahim, Osman (BioMed Central, 2012-09-11)
    INTRODUCTION: Most individuals infected with human immunodeficiency virus-1, in the absence of antiretroviral therapy, exhibit persistent virus replication and declining CD4+ cell numbers, and progress to acquired ...
  • Post-procedural Bacillus cereus septic arthritis in a patient with systemic lupus erythematosus 
    Mitton, Barend C.; Rule, Roxanne; Mbelle, Nontombi Marylucy; Van Hougenhouck-Tulleken, W.G. (Wesley); Said, Mohamed (AOSIS Open Journals, 2020-08-20)
    INTRODUCTION : Bacillus species are often considered as contaminants when cultured from clinical samples. Bacillus cereus may be a pathogen in certain circumstances and is known to cause musculoskeletal infections. This ...
  • Potential for maternally administered vaccine for infant group B streptococcus 
    Madhi, Shabir A.; Anderson, Annaliesa S.; Absalon, Judith; Radley, David; Simon, Raphael; Jongihlati, Babalwa; Strehlau, Renate; Van Niekerk, Anika M.; Izu, Alane; Naidoo, Niree; Kwatra, Gaurav; Ramsamy, Yogandree; Said, Mohamed; Jones, Stephanie; Jose, Lisa; Fairlie, Lee; Barnabas, Shaun L.; Newton, Ryan; Munson, Samantha; Jefferies, Zahra; Pavliakova, Danka; Silmon de Monerri, Natalie C.; Gomme, Emily; Perez, John L.; Scott, Daniel A.; Gruber, William C.; Jansen, Kathrin U. (Massachusetts Medical Society, 2023-07)
    BACKGROUND : Natural history studies have correlated serotype-specific anti–capsular polysaccharide (CPS) IgG in newborns with a reduced risk of group B streptococcal disease. A hexavalent CPS–cross-reactive material 197 ...
  • Potential mosquito vectors for Shuni Virus, South Africa, 2014-2018 
    Guarido, Milehna M.; Motlou, Thopisang; Riddin, Megan A.; MacIntyre, Caitlin; Manyana, Sontaga Cris; Johnson, Todd; Schrama, Maarten; Gorsich, Erin E.; Brooke, Basil D.; Almeida, Antonio Paulo Gouveia; Venter, Marietjie (Centers for Disease Control and Prevention, 2021-12)
    Shuni virus is associated with neurologic and febrile illness in animals and humans. To determine potential vectors, we collected mosquitoes in South Africa and detected the virus in species of the genera Mansonia, Culex, ...
  • Pre-detection history of extensively drug-resistant tuberculosis in KwaZulu-Natal, South Africa 
    Brown, Tyler S.; Challagundla, Lavanya; Baugh, Evan H.; Omar, Shaheed Vally; Mustaev, Arkady; Auld, Sara C.; Shah, N. Sarita; Kreiswirth, Barry N.; Brust, James C.M.; Nelson, Kristin N.; Narechania, Apurva; Kurepina, Natalia; Mlisana, Koleka; Bonneau, Richard; Eldholm, Vegard; Ismail, Nazir Ahmed; Kolokotronis, Sergios-Orestis; Robinson, D. Ashley; Gandhi, Neel R.; Mathema, Barun (National Academy of Sciences, 2019-11)
    Antimicrobial-resistant (AMR) infections pose a major threat to global public health. Similar to other AMR pathogens, both historical and ongoing drug-resistant tuberculosis (TB) epidemics are characterized by transmission ...
  • Predicting the environmental suitability for onchocerciasis in Africa as an aid to elimination planning 
    Ahmadpour, Ehsan; Beshir Ahmed, Muktar; Akalu, Temesgen Yihunie; Al- Aly, Ziyad; Alanezi, Fahad Mashhour; Alanzi, Turki M.; Alipour, Vahid; Andrei, Catalina Liliana; Ansari, Fereshteh; Ansha, Mustafa Geleto; Anvari, Davood; Appiah, Seth Christopher Yaw; Arabloo, Jalal; Arnold, Benjamin F.; Ausloos, Marcel; Ayanore, Martin Amogre; Baig, Atif Amin; Banach, Maciej; Barac, Aleksandra; Barnighausen, Till Winfried; Bayati, Mohsen; Bhattacharyya, Krittika; Bhutta, Zulfiqar A.; Bibi, Sadia; Bijani, Ali; Bohlouli, Somayeh; Bohluli, Mahdi; Brady, Oliver J.; Bragazzi, Nicola Luigi; Butt, Zahid A.; Carvalho, Felix; Chatterjee, Souranshu; Chattu, Vijay Kumar; Chattu, Soosanna Kumary; Cormier, Natalie Maria; Dahlawi, Saad M.A.; Damiani, Giovanni; Daoud, Farah; Darwesh, Aso Mohammad; Daryani, Ahmad; Deribe, Kebede; Dharmaratne, Samath Dhamminda; Diaz, Daniel; Do, Hoa Thi; Zaki, Maysaa El Sayed; Tantawi, Maha El; Elemineh, Demelash Abewa; Faraj, Anwar; Harandi, Majid Fasihi; Fatahi, Yousef; Feigin, Valery L.; Fernandes, Eduarda; Foigt, Nataliya A.; Foroutan, Masoud; Franklin, Richard Charles; Gubari, Mohammed Ibrahim Mohialdeen; Guido, Davide; Guo, Yuming; Haj-Mirzaian, Arvin; Abdullah, Kanaan Hamagharib; Hamidi, Samer; Herteliu, Claudiu; De Hidru, Hagos Degefa; Higazi, Tarig B.; Hossain, Naznin; Hosseinzadeh, Mehdi; Househ, Mowafa; Ilesanmi, Olayinka Stephen; Ilic, Milena D.; Ilic, Irena M.; Iqbal, Usman; Irvani, Seyed Sina Naghibi; Jha, Ravi Prakash; Joukar, Farahnaz; Jozwiak, Jacek Jerzy; Kabir, Zubair; Kalankesh, Leila R.; Kalhor, Rohollah; Matin, Behzad Karami; Karimi, Salah Eddin; Kasaeian, Amir; Kavetskyy, Taras; Kayode, Gbenga A.; Karyani, Ali Kazemi; Kelbore, Abraham Getachew; Keramati, Maryam; Khalilov, Rovshan; Khan, Ejaz Ahmad; Khan, Md Nuruzzaman Nuruzzaman; Khatab, Khaled; Khater, Mona M.; Kianipour, Neda; Kibret, Kelemu Tilahun; Kim, Yun Jin; Kosen, Soewarta; Krohn, Kris J.; Kusuma, Dian; La Vecchia, Carlo; Lansingh, Charles; Lee, Paul H.; LeGrand, Kate E.; Li, Shanshan; Longbottom, Joshua; Abd El Razek, Hassan Magdy; Abd El Razek, Muhammed Magdy; Maleki, Afshin; Mamun, Abdullah A.; Manafi, Ali; Manafi, Navid; Mansournia, Mohammad Ali; Martins- Melo, Francisco Rogerlandio; Mazidi, Mohsen; McAlinden, Colm; Meharie, Birhanu Geta; Mendoza, Walter; Mengesha, Endalkachew Worku; Mengistu, Desalegn Tadese; Mereta, Seid Tiku; Mestrovic, Tomislav; Miller, Ted R.; Miri, Mohammad; Moghadaszadeh, Masoud; Mohammadian-Hafshejani, Abdollah; Mohammadpourhodki, Reza; Mohammed, Shafiu; Mohammed, Salahuddin; Moradi, Masoud; Moradzadeh, Rahmatollah; Moraga, Paula; Mosser, Jonathan F.; Naderi, Mehdi; Nagarajan, Ahamarshan Jayaraman; Naik, Gurudatta; Negoi, Ionut; Nguyen, Cuong Tat; Nguyen, Huong Lan Thi; Nguyen, Trang Huyen; Nikbakhsh, Rajan; Oancea, Bogdan; Olagunju, Tinuke O.; Olagunju, Andrew T.; Bali, Ahmed Omar; Onwujekwe, Obinna E.; Pana, Adrian; Pourjafar, Hadi; Rahim, Fakher; Rahman, Mohammad Hifz Ur; Rathi, Priya; Rawaf, Salman; Rawaf, David Laith; Rawassizadeh, Reza; Resnikoff, Serge; Reta, Melese Abate; Rezapour, Aziz; Rubagotti, Enrico; Rubino, Salvatore; Sadeghi, Ehsan; Saghafipour, Abedin; Sajadi, S. Mohammad (Public Library of Science, 2021-07-28)
    Recent evidence suggests that, in some foci, elimination of onchocerciasis from Africa may be feasible with mass drug administration (MDA) of ivermectin. To achieve continental elimination of transmission, mapping surveys ...
  • Prevalence and detection of Trichomonas vaginalis in HIV-infected pregnant women 
    Price, Collin M.; Peters, Remco P.H.; Steyn, Janré; Mudau, Maanda; Olivier, Dawie; De Vos, Lindsey; Morikawa, Erika; Kock, Marleen M.; Medina-Marino, Andrew; Klausner, Jeffrey D. (Lippincott, Williams and Wilkins, 2018-05)
    BACKGROUND : Trichomonas vaginalis is a sexually transmitted infection associated with increased transmission of HIV and significant adverse birth outcomes; culture and polymerase chain reaction (PCR) are commonly used in ...
  • Prevalence and trends of Staphylococcus aureus bacteraemia in hospitalized patients in South Africa, 2010 to 2012 : laboratory-based surveillance mapping of antimicrobial resistance and molecular epidemiology 
    Perovic, Olga; Iyaloo, Samantha; Kularatne, Ranmini; Lowman, Warren; Bosman, Noma; Wadula, Jeannette; Seetharam, Sharona; Duse, Adriano; Mbelle, Nontombi Marylucy; Bamford, Colleen; Dawood, Halima; Mahabeer, Yesholata; Bhola, Prathna; Abrahams, Shareef; Singh-Moodley, Ashika (Public Library of Science, 2015-12-31)
    INTRODUCTION We aimed to obtain an in-depth understanding on recent antimicrobial resistance trends and molecular epidemiology trends of S. aureus bacteraemia (SAB). METHODS Thirteen academic centres in South Africa ...