Browsing Research Articles (Medical Microbiology) by Title

Browsing Research Articles (Medical Microbiology) by Title

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  • Assessment of Atopobium vaginae and Gardnerella vaginalis concentrations in a cohort of pregnant South African women 
    Redelinghuys, Mathys J.; Ehlers, Marthie Magdaleen; Bezuidenhout, J.E.; Becker, Piet J.; Kock, Marleen M. (BMJ Publishing Group, 2017-09)
    OBJECTIVES : The purpose of this cross-sectional study was to assess Atopobium vaginae and Gardnerella vaginalis concentrations in pregnant women of different age groups, gestational age groups, vaginal flora categories ...
  • Assessment of epidemiological and genetic characteristics and clinical outcomes of resistance to bedaquiline in patients treated for rifampicin-resistant tuberculosis : a cross-sectional and longitudinal study 
    Ismail, Nazir Ahmed; Omar, Shaheed Vally; Moultrie, Harry; Bhyat, Zaheda; Conradie, Francesca; Enwerem, M.; Ferreira, Hannetjie; Hughes, Jennifer; Joseph, Lavania; Kock, Yulene; Letsaolo, Vancy; Maartens, Gary; Meintjes, Graeme; Ngcamu, Dumisani; Okozi, Nana; Padanilam, Xavier; Reuter, Anja; Romero, Rodolfo; Schaaf, Simon; Te Riele, Julian; Variava, Ebrahim; Van der Meulen, Minty; Ismail, Farzana; Ndjeka, Norbert (Elsevier, 2022-04)
    BACKGROUND : Bedaquiline improves outcomes of patients with rifampicin-resistant and multidrug-resistant (MDR) tuberculosis; however, emerging resistance threatens this success. We did a cross-sectional and longitudinal ...
  • The association between vaginal microbiota dysbiosis, bacterial vaginosis, and aerobic vaginitis, and adverse pregnancy outcomes of women living in Sub-Saharan Africa : a systematic review 
    Juliana, Naomi C.A.; Suiters, Meghan J.M.; Al-Nasiry, Salwan; Morre, Servaas A.; Peters, Remco P.H.; Ambrosino, Elena (Frontiers Media, 2020-12)
    BACKGROUND: Previous studies have described the association between dysbiosis of the vaginal microbiota (VMB) and related dysbiotic conditions, such as bacterial vaginosis (BV) and aerobic vaginitis (AV), and various adverse ...
  • Autophagy, Inflammation, and Metabolism (AIM) Center in its second year 
    Deretic, Vojo; Prossnitz, Eric; Burge, Mark; Campen, Matthew J.; Cannon, Judy; Liu, Ke Jian; Liu, Meilian; Hall, Pamela; Sklar, Larry A.; Allers, Lee; Mariscal, Luisa; Garcia, Sally Ann; Weaver, John; Baehrecke, Eric H.; Behrends, Christian; Cecconi, Francesco; Codognoe, Patrice; Chen, Guang-Chao; Elazar, Zvulun; Eskelinen, Eeva-Liisa; Gozuacik, Devrim; Hong, Wanjin; Jo, Eun-Kyeong; Johansen, Terje; Juhasz, Gabor; Kimchi, Adi; Ktistakis, Nicholas; Kroemer, Guido; Mizushima, Noboru; Munz, Christian; Reggiori, Fulvio; Rubinsztein, David; Ryan, Kevin; Schroder, Kate; Shen, Han-Min; Simonsen, Anne; Tooze, Sharon A.; Vaccaro, Maria; Yoshimori, Tamotsu; Yu, Li; Zhang, Hong; Klionsky, Daniel J. (Taylor and Francis, 2019)
    The NIH-funded center for autophagy research named Autophagy, Inflammation, and Metabolism (AIM) Center of Biomedical Research Excellence, located at the University of New Mexico Health Science Center is now completing its ...
  • Autophagy, Inflammation, and Metabolism (AIM) Center of Biomedical Research Excellence : supporting the next generation of autophagy researchers and fostering international collaborations 
    Deretic, Vojo; Prossnitz, Eric; Burge, Mark; Campen, Matthew J.; Cannon, Judy; Liu, Ke Jian; Sklar, Larry A.; Allers, Lee; Garcia, Sally Ann; Baehrecke, Eric H.; Behrends, Christian; Cecconi, Francesco; Codogno, Patrice; Chen, Guang-Chao; Elazar, Zvulun; Eskelinen, Eeva-Liisa; Fourie, P.B. (Petrus Bernardus); Gozuacik, Devrim; Hong, Wanjin; Hotamisligi, Gokhan; Jaattela, Marja; Jo, Eun-Kyeong; Johansen, Terje; Juhasz, Gábor; Kimchi, Adi; Ktistakis, Nicholas; Kroemer, Guido; MIzushima, Noboru; Munz, Christian; Reggiori, Fulvio; Rubinsztein, David; Ryan, Kevin; Schroder, Kate; Simonsen, Anne; Tooze, Sharon; Vaccaro, Maria I.; Yoshimori, Tamotsu; Yu, Li; Zhang, Hong; Klionsky, Daniel J. (Taylor and Francis, 2018)
    Recently, NIH has funded a center for autophagy research named the Autophagy, Inflammation, and Metabolism (AIM) Center of Biomedical Research Excellence, located at the University of New Mexico Health Science Center (UNM ...
  • Awaking a sleeping epidemic 
    Van Coller, Riaan; Van Rensburg, Elna; Schutte, Clara-Maria; Brink, Delene; Welthagen, Gerhard Frederick; Dove, Mike G. (South African Medical Association, 2007-04)
    Two patients with African sleeping sickness (SS) presented to the neurology unit, Pretoria Academic Hospital, during 2004 and 2005. SS has shown a recent resurgence, with epidemics in the Sudan, Angola and the Democratic ...
  • Bacterial profile among patients with suspected bloodstream infections in Ethiopia : a systematic review and meta-analysis 
    Alemnew, Birhan; Biazin, Habtamu; Demis, Asmamaw; Reta, Melese Abate (Hindawi, 2020-09)
    The burden of bloodstream infections (BSIs) has been warranted in Ethiopia. Globally, the emergency and raised resistance rate of bacterial antimicrobial resistance is becoming a prominent problem, and it is difficult to ...
  • Bacterial vaginosis : current diagnostic avenues and future opportunities 
    Redelinghuys, Mathys J.; Geldenhuys, Janri; Jung, Hyun-Sul; Kock, Marleen M. (Frontiers Media, 2020-08-11)
    A healthy female genital tract harbors a microbiome dominated by lactic acid and hydrogen peroxide producing bacteria, which provide protection against infections by maintaining a low pH. Changes in the bacterial ...
  • Bedaquiline and clofazimine : successes and challenges 
    Ndjeka, Norbert; Ismail, Nazir Ahmed (Elsevier, 2020-08)
    Bedaquiline, a novel therapeutic drug, and clofazimine, a re-purposed drug, are front-line therapies recommended by WHO to treat rifampicin-resistant or multidrugresistant tuberculosis. Both drugs have been in use ...
  • Biolog for the determination of microbial diversity in activated sludge systems 
    Van Heerden, J.; Ehlers, Marthie Magdaleen; Cloete, Thomas Eugene (Elsevier, 2001)
    In this study, different carbon source profiles were generated by inoculating Biolog GN microwell plates, with different dilutions of microbial communities from a number of activated sludge systems. This led to the successful ...
  • Biting off more than you can chew : microbiological flora isolated from human and animal bite wounds 
    Visser, Adele; Visser, Hilgaard Frans (Media 24 & South African Orthopaedic Association, 2012)
    BACKGROUND: Bite wounds, from human and animal origin, can lead to significant complications if appropriate therapy is not undertaken timeously. A basic knowledge of the microbiological flora is essential for each clinical ...
  • A broad profile of co-dominant epitopes shapes the peripheral mycobacterium tuberculosis specific CD8+ T-Cell immune response in South African patients with active tuberculosis 
    Axelsson-Robertson, Rebecca; Loxton, Andre G.; Walzl, Gerhard; Ehlers, Marthie Magdaleen; Kock, Marleen M.; Zumla, Alimuddin; Maeurer, Markus; Scriba, Thomas Jens (Public Library of Science, 2013-03-26)
  • A call to standardize the definition and method of assessing women for vaginal discharge syndrome in pregnancy 
    Babalola, Chibuzor M.; Peters, Remco P.H.; Mukomana, Freedom; Mdingi, Mandisa; Gigi, Ranjana M.S.; Muzny, Christina A.; Taylor, Christopher M.; Medina-Marino, Andrew; Klausner, Jeffrey D (Oxford University Press, 2023-04)
    No abstract available.
  • Carbapenemase-producing Klebsiella pneumoniae : a key pathogen set for global nosocomial dominance 
    Pitout, Johann D.D.; Nordmann, Patrice; Poirel, Laurent (American Society for Microbiology, 2015-10)
    The management of infections due to Klebsiella pneumoniae has been complicated by the emergence of antimicrobial resistance, especially to the carbapenems. Resistance to the carbapenems in K. pneumoniae involves multiple ...
  • A case report of Nocardia asiatica constrictive pericarditis in a patient with Human Immunodeficiency Virus 
    Griessel, Rosemary; Mitton, Barend C.; Rule, Roxanne; Said, Mohamed (Elsevier, 2022-05)
    Nocardiosis commonly affects the respiratory system and is a rare cause of purulent pericarditis. Invasive nocardial infections occur more frequently in patients with immunosuppression. A misdiagnosis as tuberculosis ...
  • Case-fatality and sequelae following acute bacterial meningitis in South Africa, 2016 through 2020 
    Meiring, Susan; Cohen, Cheryl; De Gouveia, Linda; Du Plessis, Mignon; Quan, Vanessa; Kleynhans, Jackie; Menezes, Colin; Reubenson, Gary; Dawood, Halima; Nchabeleng, Maphoshane; Said, Mohamed; Mvelase, Nomonde; Mahabeer, Prasha; Chomba, Rispah; Lekalakala, Ruth; Nana, Trusha; Chibabhai, Vindana; Black, Marianne; Von Gottberg, Anne (Elsevier, 2022-09)
    OBJECTIVES : Providing country-specific estimates of case fatality and sequelae from bacterial meningitis (BM) is important to evaluate and monitor progress toward the World Health Organization's roadmap to “defeating ...
  • Causes of hyperferritinaemia classified by HIV status in a tertiary-care setting in South Africa 
    Visser, Adele; Mostert, Chris J. (Cambridge University Press, 2012-03)
    This study included all patients, with known HIV-1 status, admitted to hospital over a 5-year period with serum ferritin values exceeding 1500 mg/l. Markedly elevated serum ferritin levels are associated with a host of ...
  • CD4+ T cell responses to Toxoplasma gondii are a double-edged sword 
    El Bissati, Kamal; Krishack, Paulette A.; Zhou, Ying; Weber, Christopher R.; Lykins, Joseph; Jankovic, Dragana; Edelblum, Karen L.; Fraczek, Laura; Grover, Harshita; Chentoufi, Aziz Alami; Singh, Gurminder; Reardon, Catherine; Dubey, J.P.; Reed, Steve; Alexander, Jeff; Sidney, John; Sette, Alessandro; Shastri, Nilabh; McLeod, Rima (MDPI, 2023-09-14)
    CD4+ T cells have been found to play critical roles in the control of both acute and chronic Toxoplasma infection. Previous studies identified a protective role for the Toxoplasma CD4+ T celleliciting peptide AS15 ...
  • The Centre for Tuberculosis : from reference laboratory to public health institution 
    Ismail, Nazir Ahmed; Ihekweazu, Chikwe; Koornhof, Hendrik; Madhi, Shabir A. (Federation of Infectious Diseases Societies of South Africa, 2012)
    Tuberculosis (TB) continues to be one of the biggest public health challenges of our time, and as epidemiology of the disease evolves in an era of high HIV prevalence in South Africa, so must the response. With exciting ...
  • The changing global epidemic of HIV and ocular disease 
    Peters, Remco P.H.; Kestelyn, Philippe G.; Zierhut, Manfred; Kempen, John H. (Taylor and Francis, 2020)
    PURPOSE : Overview of the evolving epidemiology of human immunodeficiency virus (HIV)-related ocular disease over time. METHOD : Narrative review. RESULTS : HIV enhances susceptibility to opportunistic eye infections, ...