Browsing Research Articles (Biochemistry) by Title

Browsing Research Articles (Biochemistry) by Title

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  • Discovery of compounds blocking the proliferation of toxoplasma gondii and plasmodium falciparum in a chemical space based on piperidinyl-benzimidazolone analogs 
    Saidani, Nadia; Botte, Cyrille Y.; Deligny, Michael; Bonneau, Anne-Laure; Reader, Janette; Lasselin, Ronald; Merer, Goulven; Niepceron, Alisson; Brossier, Fabien; Cintrat, Jean-Christophe; Rousseau, Bernard; Birkholtz, Lyn-Marie; Cesbron-Delauw, Marie-France; Dubremetz, Jean-François; Mercier, Corinne; Vial, Henri; Lopez, Roman; Marechal, Eric (American Society for Microbiology, 2014-05)
    A piperidinyl-benzimidazolone scaffold has been found in the structure of different inhibitors of membrane glycerolipid metabolism, acting on enzymes manipulating diacylglycerol and phosphatidic acid. Screening a focus ...
  • Discovery of novel alkylated (bis)urea and (bis)thiourea polyamine analogues with potent antimalarial activities 
    Verlinden, Bianca K.; Niemand, Jandeli; Snyman, Janette; Sharma, Shirv K.; Beattie, Ross J.; Woster, Partick M.; Birkholtz, Lyn-Marie (American Chemical Society, 2011-10)
    A series of alkylated (bis)urea and (bis)thiourea polyamine analogues were synthesized and screened for antimalarial activity against chloroquine-sensitive and -resistant strains of Plasmodium falciparum in vitro. All ...
  • Discovery-2 : an interactive resource for the rational selection and comparison of putative drug target proteins in malaria 
    Mpangase, Phelelani Thokozani; Szolkiewicz, Michal Jerzy; Le Grange, Misha; Smit, Jeanre H.; Burger, Pieter Buys; Joubert, Fourie (BioMed Central, 2013-03-28)
    BACKGROUND: Drug resistance to anti-malarial compounds remains a serious problem, with resistance to newer pharmaceuticals developing at an alarming rate. The development of new anti-malarials remains a priority, and ...
  • Distinct expression and methylation patterns for genes with different fates following a single whole-genome duplication in flowering plants 
    Shi, Tao; Rahmani, Razgar Seyed; Gugger, Paul F.; Wang, Muhua H.; Li, Hui; Zhang, Yue; Li, Zhizhong; Wang, Qingfeng; Van de Peer, Yves; Marchal, Kathleen; Chen, Jinming (Oxford University Press, 2020-08)
    For most sequenced flowering plants, multiple whole-genome duplications (WGDs) are found. Duplicated genes following WGD often have different fates that can quickly disappear again, be retained for long(er) periods, or ...
  • Distribution and evolution of nonribosomal peptide synthetase gene clusters in the Ceratocystidaceae 
    Sayari, Mohammad; Van der Nest, Magrieta Aletta; Steenkamp, Emma Theodora; Soal, Nicole Christine; Wilken, Pieter Markus; Wingfield, Brenda D. (MDPI Publishing, 2019-04-30)
    In filamentous fungi, genes in secondary metabolite biosynthetic pathways are generally clustered. In the case of those pathways involved in nonribosomal peptide production, a nonribosomal peptide synthetase (NRPS) gene ...
  • Distribution and genetic diversity of five invasive pests of Eucalyptus in sub-Saharan Africa 
    Wondafrash, Mesfin; Slippers, Bernard; Nambazimana, Alphonsine; Kayumba, Isaac; Nibouche, Samuel; Van der Lingen, Simon; Asfaw, Birhane A.; Jenya, Herbert; Mutitu, Eston K.; Makowe, Idea A.; Chungu, Donald; Kiwuso, Peter; Kiwuso, Peter; Kulimushi, Emmanuel; Razafindrakotomamonjy, Andrianantenaina; Bosu, Paul P.; Sookar, Preeaduth; Hurley, Brett Phillip (Springer, 2020-07)
    Eucalyptus is one of the most planted tree genera across the world, but is heavily challenged by invasive insect pests originating from the native range of these trees. The rate of introduction of non-native Eucalyptus-feeding ...
  • Distribution of Gonipterus species and their egg parasitoids in Australia : implications for biological control 
    Schroder, Michelle L.; Nahrung, Helen F.; De Souza, Natalia M.; Lawson, Simon A.; Slippers, Bernard; Wingfield, Michael J.; Hurley, Brett Phillip (MDPI, 2021-07-22)
    Gonipterus species are pests of Eucalyptus plantations worldwide. The egg parasitoid wasp Anaphes nitens is used in many countries for the biological control of Gonipterus spp. Recent taxonomic studies have shown that ...
  • Distribution of horizontally transferred heavy metal resistance operons in recent outbreak bacteria 
    Reva, Oleg N.; Bezuidt, Keoagile Ignatius Oliver (Landes Bioscience, 2012-03)
    Mankind is confronted by the outbreaks of highly virulent and multi-drug resistant pathogens. The outbreak strains often belong to wellknown disease-associated species belonging to genera such as Salmonella, Klebsiella ...
  • The distribution of onion virulence gene clusters among Pantoea spp. 
    Stice, Shaun P.; Shin, Gi Yoon; De Armas, Stefanie; Koirala, Santosh; Galvan, Guillermo A.; Siri, Maria Ines; Severns, Paul M.; Coutinho, Teresa A.; Dutta, Bhabesh; Kvitko, Brian H. (Frontiers Media, 2021-03)
    Pantoea ananatis is a gram-negative bacterium and the primary causal agent of center rot of onions in Georgia. Previous genomic studies identified two virulence gene clusters, HiVir and alt, associated with center rot. ...
  • Diversity and evolution of polyketide biosynthesis gene clusters in the Ceratocystidaceae 
    Sayari, Mohammad; Steenkamp, Emma Theodora; Van der Nest, Magrieta Aletta; Wingfield, Brenda D. (Elsevier, 2018-09)
    Polyketides are low-molecular weight secondary metabolites with diverse biological activities. Polyketide synthase (PKS) and other proteins responsible for producing these compounds are often encoded from genes that are ...
  • Diversity and seasonality of fungal communities in soil from the Succulent Karoo biodiversity hotspot, South Africa 
    Pieterse, Zelda; Aveling, T.A.S. (Terry); Jacobs, Adriana; Cowan, Don A. (Elsevier, 2020-01)
    The fungal rhizosphere communities associated with soil surrounding Aizoaceae plants in the Namaqua National Park in the Succulent Karoo biodiversity hotspot, South Africa, were analysed by culture-dependent and ...
  • Diversity of glycosyl hydrolases from cellulose-depleting communities enriched from casts of two earthworm species 
    Beloqui, Ana; Nechitaylo, Taras Y.; Lopez-Cortes, Nieves; Ghazi, Azam; Guazzaroni, Maria-Eugenia; Polaina, Julio; Strittmatter, Axel W.; Reva, Oleg N.; Waliczek, Agnes; Yakimov, Michail M.; Golyshina, Olga V.; Ferrer, Manuel; Golyshin, Peter N. (American Society for Microbiology, 2010-09)
    The guts and casts of earthworms contain microbial assemblages that process large amounts of organic polymeric substrates from plant litter and soil; however, the enzymatic potential of these microbial communities remains ...
  • Diversity structure of the microbial communities in the guts of four neotropical termite species 
    Vikram, Surendra; Arneodo, Joel D.; Calcagno, Javier; Ortiz, Maximiliano; Mon, Maria Laura; Etcheverry, Clara; Cowan, Don A.; Talia, Paola (PeerJ, 2021-04-07)
    The termite gut microbiome is dominated by lignocellulose degrading microorganisms. This study describes the intestinal microbiota of four Argentinian higher termite species with different feeding habits: Microcerotermes ...
  • DNA metabarcoding of microbial communities for healthcare 
    Zaets, I.YE.; Podolich, O.V.; Reva, Oleg N.; Kozyrovska, Natalia (Institute of Molecular Biology and Genetics, National Academy of Sciences of Ukraine, 2016)
    High-throughput sequencing allows obtaining DNA barcodes of multiple species of microorganisms from a single environmental sample. Next Generation Sequencing (NGS)-based profiling provides new opportunities to evaluate ...
  • Does the applicability of Bacillus strains in probiotics rely upon their taxonomy? 
    Safronova, L.A.; Zelena, L.B.; Klochko, V.V.; Reva, Oleg N. (NRC Research Press, 2012-02)
    The taxonomic position and biological activities of two Bacillus strains used in veterinary probiotics were studied in this work. These microorganisms inhibit growth of a broad spectrum of pathogenic cultures. They ...
  • Doing it alone : unisexual reproduction in filamentous ascomycete fungi 
    Wilson, Andi M.; Gabriel, Raphael; Singer, Steven W.; Schuerg, Timo; Wilken, Pieter Markus; Van der Nest, Magrieta Aletta; Wingfield, Michael J.; Wingfield, Brenda D. (Elsevier, 2021-03)
    Unisexuality in fungi is the result of sexual reproduction in a single isolate that harbors genes associated with only a single mating type. To date, unisexual reproduction has been described in only three genera of ...
  • Draft genome assembly of the false spider mite Brevipalpus yothersi 
    Navia, Denise; Novelli, Valdenice M.; Rombauts, Stephane; Freitas-Astua, Juliana; Santos de Mendonca, Renata; Nunes, Maria Andreia; Machado, Marcos A.; Lin, Yao-Cheng; Le, Phuong; Zhang, Zaichao; Grbic, Miodrag; Wybouw, Nicky; Breeuwer, Johannes A. J.; Van Leeuwen, Thomas; Van de Peer, Yves (American Society for Microbiology, 2019-02-07)
    The false spider mite Brevipalpus yothersi infests a broad host plant range and has become one of the most economically important species within the genus Brevipalpus. This phytophagous mite inflicts damage by both feeding ...
  • Draft genome assembly of the poultry red mite, Dermanyssus gallinae 
    Burgess, Stewart T.G.; Bartley, Kathryn; Nunn, Francesca; Wright, Harry W.; Hughes, Margaret; Gemmell, Matthew; Haldenby, Sam; Paterson, Steve; Rombauts, Stephane; Tomley, Fiona M.; Blake, Damer P.; Pritchard, James; Schicht, Sabine; Strube, Christina; Oines, Oines; Van Leeuwen, Thomas; Van de Peer, Yves; Nisbet, Alasdair J. (American Society for Microbiology, 2018-11-08)
    The poultry red mite, Dermanyssus gallinae, is a major worldwide concern in the egg-laying industry. Here, we report the first draft genome assembly and gene prediction of Dermanyssus gallinae, based on combined PacBio ...
  • Draft genome of Cercospora zeina, Fusarium pininemorale, Hawksworthiomyces lignivorus, Huntiella decipiens and Ophiostoma ips 
    Wingfield, Brenda D.; Berger, David Kenneth; Steenkamp, Emma Theodora; Lim, Hye-Jin; Duong, Tuan A.; Bluhm, Burton H.; De Beer, Z. Wilhelm; De Vos, Lieschen; Fourie, Gerda; Naidoo, Kershney; Olivier, Nicholas Abraham; Lin, Yao-Cheng; Van de Peer, Yves; Joubert, Fourie; Crampton, Bridget Genevieve; Swart, Velushka; Soal, Nicole Christine; Tatham, Catherine; Van der Nest, Magrieta Aletta; Van der Merwe, Nicolaas Albertus (Albie); Van Wyk, Stephanie; Wilken, Pieter Markus; Wingfield, Michael J. (International Mycological Association, 2017-11-21)
    The genomes of Cercospora zeina, Fusarium pininemorale, Hawksworthiomyces lignivorus, Huntiella decipiens, and Ophiostoma ips are presented in this genome announcement. Three of these genomes are from plant pathogens and ...
  • The draft genome of Deladenus siricidicola 
    Postma, Alisa; Mlonyeni, X.O.M. (Xolile Osmond Mnyamezeli); Clasen, Frederick Johannes; Joubert, Fourie; Slippers, Bernard (Exeley, 2019)
    The nematode Deladenus siricidicola is used as biological control agent against the invasive woodwasp Sirex noctilio, a serious invasive pest of Pinus plantations globally. The draft genome of this ecologically ...