Browsing Research Articles (School of Health Systems and Public Health (SHSPH)) by UP Author "Patrick, Sean Mark"
- UPSpace Home
- →
- Health Sciences
- →
- School of Health Systems and Public Health (SHSPH)
- →
- Research Articles (School of Health Systems and Public Health (SHSPH))
- →
- Browsing Research Articles (School of Health Systems and Public Health (SHSPH)) by UP Author
JavaScript is disabled for your browser. Some features of this site may not work without it.
Browsing Research Articles (School of Health Systems and Public Health (SHSPH)) by UP Author "Patrick, Sean Mark"
Now showing items 1-16 of 16
-
Jaratlerdsiri, Weerachai; Jiang, Jue; Gong, Tingting; Patrick, Sean Mark; Willet, Cali; Chew, Tracy; Lyons, Ruth J.; Haynes, Anne-Maree; Pasqualim, Gabriela; Louw, Melanie; Kench, James G.; Campbell, Raymond; Horvath, Lisa G.; Chan, Eva K.F.; Wedge, David C.; Sadsad, Rosemarie; Brum, Ilma Simoni; Mutambirwa, Shingai B.A.; Stricker, Phillip D.; Bornman, Maria S. (Riana); Hayes, Vanessa M. (Nature Research, 2022-09)Prostate cancer is characterized by considerable geo-ethnic disparity. African ancestry is a significant risk factor, with mortality rates across sub-Saharan Africa of 2.7-fold higher than global averages. The contributing ...
-
Bornman, Maria S. (Riana); Delport, Rhena; Farías, Paulina; Aneck-Hahn, Natalie Hildegard; Patrick, Sean Mark; Millar, Robert P.; De Jager, Christiaan (Elsevier, 2018-04)DDT [1, 1, 1-trichloro-2,2-bis (p-chlorophenyl)-ethane] compounds are used for indoor residual spraying (IRS) to control malaria mosquitoes. DDT is an endocrine disruptor chemical in experimental conditions, but little is ...
-
Craddock, Jenna; Jiang, Jue; Patrick, Sean Mark; Mutambirwa, Shingai B.A.; Stricker, Phillip D.; Bornman, Maria S. (Riana); Jaratlerdsiri, Weerachai; Hayes, Vanessa M. (MDPI, 2023-07)African ancestry is a significant risk factor for aggressive prostate cancer (PCa), with southern African ethnicity conferring a nearly 3-fold increased global risk for associated mortality. It is well understood that ...
-
Patrick, Sean Mark; Cox, Sarah N.; Guidera, Kathryn E.; Simon, Molly J.; Kruger, Taneshka; Bornman, Maria S. (Riana) (Taylor and Francis, 2022)The global Coronavirus disease 2019 (COVID-19) pandemic has resulted in public health, political, scientific and private sector response at an unprecedented scale. However, this shift in focus has caused widespread disruption ...
-
Letsoalo, Kganya; Nortje, Evangeline; Patrick, Sean Mark; Nyakudya, Trevor Tapiwa; Hlophe, Yvette Nkondo (Wiley, 2024-03)Melanoma, an invasive class of skin cancer, originates from mutations in melanocytes, the pigment-producing cells. Globally, approximately 132,000 new cases are reported each year, and in South Africa, the incidence stands ...
-
Patrick, Sean Mark; Bornman, Maria S. (Riana); Joubert, Annie M.; Pitts, Neville; Naidoo, Vinny; De Jager, Christiaan (Elsevier, 2016-06)The male reproductive system is sensitive to endocrine disrupting chemicals (EDCs) during critical developmental windows. Male Sprague-Dawley rats were exposed in utero-, during lactation- and directly to 1,1,1-trichloro ...
-
Patrick, Sean Mark; De Jager, Christiaan; Bornman, Maria S. (Riana); Joubert, Annie M. (Suid Afrikaanse Akademie vir Wetenskap & Kuns, 2012)Endocrine disrupting chemicals may disrupt hormonal processes leading to impaired development. The studies aim was to investigate the relationship between various EDC exposures and development of urogenital system in male ...
-
Bornman, Maria S. (Riana); Aneck-Hahn, Natalie Hildegard; De Jager, Christiaan; Wagenaar, Gesina M.; Bouwman, Hindrik; Barnhoorn, Irene E.J.; Patrick, Sean Mark; Vandenberg, Laura N.; Kortenkamp, Andreas; Blumberg, Bruce; Kimmins, Sarah; Jegou, Bernard; Auger, Jacques; DiGangi, Joseph; Heindel, Jerrold J. (National Institute of Environmental Health Sciences, 2017)BACKGROUND : Africa faces a number of unique environmental challenges. Unfortunately, it lacks the infrastructure needed to support the comprehensive environmental studies that could provide the scientific basis to inform ...
-
Bradshaw, Debbie; Chopra, Mickey; Kerber, Kate; Lawn, Joy E.; Bamford, Lesley; Moodley, Jack; Pattinson, Robert Clive; Patrick, Sean Mark; Stephen, C.R. (Cindy); Velaphi, Sithembiso (Elsevier, 2008-04-12)South Africa is one of the few developing countries with a national confidential inquiry into maternal deaths. 164 health facilities obtain audit data for stillbirths and neonatal deaths, and a new audit network does so ...
-
Dieng, Sokhna; Adebayo-Ojo, Temitope Christina; Kruger, Taneshka; Riddin, Megan A.; Trehard, Helene; Tumelero, Serena; Bendiane, Marc-Karim; De Jager, Christiaan; Patrick, Sean Mark; Bornman, Maria S. (Riana); Gaudart, Jean (Nature Research, 2023)In South Africa, the population at risk of malaria is 10% (around six million inhabitants) and concern only three provinces of which Limpopo Province is the most affected, particularly in Vhembe District. As the elimination ...
-
Patrick, Sean Mark; Bendiane, Marc-Karim; Kruger, Taneshka; Harris, Bernice Nerine; Riddin, Megan A.; Trehard, Helene; De Jager, Christiaan; Bornman, Maria S. (Riana); Gaudart, Jean (BMC, 2023-05)BACKGROUND : Over the past decade, implementation of multiple malaria control strategies in most countries has largely contributed to advance the global malaria elimination agenda. Nevertheless, in some regions, seasonal ...
-
Ramatsoma, Hlologelo; Patrick, Sean Mark (Frontiers Media, 2022-03)INTRODUCTION : Hypertension is one of the leading causes of morbidity and mortality worldwide, and has been associated with target organ damage. Effects of hypertension on the auditory system are varied and requires further ...
-
Iwu, Chidozie Declan; Patrick, Sean Mark (Elsevier, 2021-10)INTRODUCTION : The Global Action Plan (GAP) on antimicrobial resistance (AMR) delivers a ‘One Health’ strategy for the development of the national action plan. It encourages the optimal use of antimicrobials and strengthens ...
-
Metagenomic analysis reveals a rich bacterial content in high‐risk prostate tumors from African men Feng, Ye; Jaratlerdsiri, Weerachai; Patrick, Sean Mark; Lyons, Ruth J.; Haynes, Anne‐Maree; Collins, Colin C.; Stricker, Phillip D.; Bornman, Maria S. (Riana); Hayes, Vanessa M. (Wiley, 2019-11)BACKGROUND : Inflammation is a hallmark of prostate cancer (PCa), yet no pathogenic agent has been identified. Men from Africa are at increased risk for both aggressive prostate disease and infection. We hypothesize that ...
-
Blackburn, James; Vecchiarelli, Stefano; Heyer, Erin E.; Patrick, Sean Mark; Lyons, Ruth J.; Jaratlerdsiri, Weerachai; Van Zyl, Smit; Bornman, Maria S. (Riana); Mercer, Tim R.; Hayes, Vanessa M. (Wiley, 2019-07)BACKGROUND : The androgen‐regulated gene TMPRSS2 to the ETS transcription factor gene ERG fusion is the most common genomic alteration acquired during prostate tumorigenesis and biased toward men of European ancestry. ...
-
Patrick, Sean Mark; Aneck-Hahn, Natalie Hildegard; Van Wyk, Susan; Van Zijl, Magdelena Catherina; Huma, Mampedi; De Jager, Christiaan (Springer, 2020-04)The contribution of veterinary growth promoters (VGP) to the environmental burden of endocrine-disrupting chemicals (EDCs) is largely unknown. At cattle feedlots, the excrement of cattle may contain VGPs, which can contaminate ...
Now showing items 1-16 of 16