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Browsing Health Sciences by Supervisor "Anderson, Ronald"
Now showing items 1-14 of 14
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(University of Pretoria, 2015)Rheumatoid arthritis (RA) is a chronic inflammatory disorder resulting in joint pain, stiffness and joint destruction. This can lead to considerable loss of physical and psycho-social function and even premature death. ...
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(University of Pretoria, 2009-05-26)The one-way mixed lymphocyte culture (MLC) is used to assess histocompatibility between donor and recipient. First introduced in 1966, this method involves the co-culture of lymphocytes from the peripheral blood of the ...
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(University of Pretoria, 2006-10-28)Please read the abstract in the section 00front of this document
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(University of Pretoria, 2016)Background: Neutrophil extracellular traps (NETs) constitute a network of chromatin fibres containing histone and antimicrobial peptides that are released by activated neutrophils. NETs protect the host against infection ...
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(University of Pretoria, 2005-09-22)The Streptococcus pneumoniae-derived toxin, pneumolysin, has been reported to augment neutrophil-mediated inflammatory responses in murine models of experimental infection of the airways, and to favour invasive pneumococcal ...
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(University of Pretoria, 2007-01-04)Please read the abstract in the section 00front of this document
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(University of Pretoria, 2010-09-20)The in vitro antimalarial activity of clofazimine and seven of its analogues, all TMP(tetramethyl-piperidyl group)-derivatives except 8669, against the R8-1 and pfUP-1 laboratory strains of Plasmodium falciparum was ...
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(University of Pretoria, 2007-01-04)The intra- and extracellular activities of 2 novel tetramethylpiperidine (TMP)-substituted phenazines, B4121 and B4128 against Mycobacterium tuberculosis H37R (ATCC 27294) were determined and compared with those of clofazimine ...
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(University of Pretoria, 2007-05-11)Moxifloxacin is considered to be a broad-spectrum fluoroquinolone due to its activity against both gram positive and gram negative bacteria. Importantly this agent is currently being evaluated in ongoing clinical trials ...
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(University of Pretoria, 2011)Montelukast (ML) is primarily an antagonist of type 1 cysteinyl leukotriene receptors (CysLT1R), an activity which underpins its therapeutic efficacy in bronchial asthma. However, ML has also been reported to be useful in ...
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(University of Pretoria, 2008-05-30)Please read the abstract in the section 00front of this document
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(University of Pretoria, 2010)The major cause of HIV-related mortality in Sub-Saharan countries is pulmonary tuberculosis (TB), which is an escalating threat due to the emergence of multidrug resistant (MDR) and extremely multidrug resistant (XDR) TB. ...
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(University of Pretoria, 2005-11-07)Neutrophils playa key role in the systemic inflammatory response which may lead to serious tissue injury and multiple organ dysfunction. In this setting, activated neutrophils, largely in response to tumour necrosis ...
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(University of Pretoria, 2006-10-28)Please read the abstract in the section 00front of this document
Now showing items 1-14 of 14