Browsing Health Sciences by Author "Ueckermann, Veronica"

Browsing Health Sciences by Author "Ueckermann, Veronica"

Sort by: Order: Results:

  • Acute intermittent porphyria mimicking Guillain–Barré syndrome in a HIV patient 
    Soma, Prashilla; Ueckermann, Veronica; Sasikumar, S.S. (Sunayana); Mashoeshoe, K.S. (Sam) (Elsevier, 2016-01)
    The diagnosis of porphyria remains challenging as the condition is characterized by a myriad of clinical and biochemical features. More importantly, an acute attack is associated with increased morbidity and mortality. ...
  • Ad26.COV2.S breakthrough infections induce high titers of neutralizing antibodies against Omicron and other SARS-CoV-2 variants of concern 
    Kitchin, Dale; Richardson, Simone I.; Van der Mescht, Mieke Adri; Motlou, Thopisang; Mzindle, Nonkululeko; Moyo-Gwete, Thandeka; Makhado, Zanele; Ayres, Frances; Manamela, Nelia P.; Spencer, Holly; Lambson, Bronwen; Oosthuysen, Brent; Kaldine, Haajira; Du Pisanie, Marizane; Mennen, Mathilda; Skelem, Sango; Williams, Noleen; Ntusi, Ntobeko A.B.; Burgers, Wendy A.; Gray, Glenda G.; Bekker, Linda-Gail; Boswell, Michael T.; Rossouw, Theresa M.; Ueckermann, Veronica; Moore, Penny L. (Cell Press, 2022-03-15)
    The Janssen (Johnson & Johnson) Ad26.COV2.S non-replicating viral vector vaccine has been widely deployed for COVID-19 vaccination programs in resource-limited settings. Here we confirm that neutralizing and binding ...
  • Antibody-dependent cellular cytotoxicity against SARS-CoV-2 Omicron sub-lineages is reduced in convalescent sera regardless of infecting variant 
    Richardson, Simone I.; Kgagudi, Prudence; Manamela, Nelia P.; Kaldine, Haajira; Venter, Elizabeth M.; Pillay, Thanusha; Lambson, Bronwen E.; Van der Mescht, Mieke Adri; Hermanus, Tandile; Balla, Sashkia R.; De Beer, Zelda; De Villiers, Talita R.; Bodenstein, Annie; Van den Berg, Gretha; Du Pisanie, Marizane; Burgers, Wendy A.; Ntusi, Ntobeko A.B.; Abdullah, Fareed; Ueckermann, Veronica; Rossouw, Theresa; Boswell, Michael T.; Moore, Penny L. (Cell Press, 2023-01)
    The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.4 and BA.5 variants caused major waves of infections. Here, we assess the sensitivity of BA.4 to binding, neutralization, and antibodydependent cellular ...
  • The association between elevated troponin levels and all cause 30 day mortality in critically ill patients seen at an Academic Hospital – a prospective cohort study 
    Joseph, Darren; Ker, James A.; Rheeder, Paul; Ueckermann, Veronica (University of Leicester, 2017-03-07)
    PURPOSES : Elevated cardiac troponins have been shown to be associated with mortality in critical care, but its utility is not well established, especially in the setting of renal failure. This study aimed to examine the ...
  • Case study : a novel use for faecal microbial transplantation 
    Ueckermann, Veronica; Francis, E.W. (NISC (Pty) Ltd, Medpharm Publications, and Informa UK Limited, 2019)
    Faecal microbiota transplantation (FMT) refers to the infusion of faeces from a healthy donor, into the gastrointestinal tract of a recipient patient. There is considerable evidence for the efficacy of FMT for the ...
  • A challenging case of hypercalcaemia 
    Ueckermann, Veronica (Health and Medical Publishing Group, 2013)
    Hypercalcaemia is not uncommon in clinical practice. The majority of cases are accounted for by hyperparathyroidism and malignancy. The patient discussed below presented with an unusual case of hypercalcaemia.
  • Comparison of platelet-and endothelial-associated biomarkers of disease activity in people hospitalized with Covid-19 with and without HIV co-infection 
    Van der Mescht, Mieke Adri; Steel, Helen C.; De Beer, Zelda; Abdullah, Fareed; Ueckermann, Veronica; Anderson, Ronald; Rossouw, Theresa (Frontiers Media, 2023-08-14)
    INTRODUCTION : SARS-CoV-2 elicits a hyper-inflammatory response that contributes to increased morbidity and mortality in patients with COVID-19. In the case of HIV infection, despite effective anti-retroviral therapy, ...
  • Comparison of targeted metagenomics and IS-Pro methods for analysing the lung microbiome 
    Goolam Mahomed, Tanweer; Peters, Remco P.H.; Pretorius, G.H.J.; Mahomed, A. Goolam; Ueckermann, Veronica; Kock, Marleen M.; Ehlers, Marthie Magdaleen (BioMed Central, 2021-08-18)
    BACKGROUND : Targeted metagenomics and IS-Pro method are two of the many methods that have been used to study the microbiome. The two methods target different regions of the 16 S rRNA gene. The aim of this study was to ...
  • COVID-19 severity and in-hospital mortality in an area with high HIV prevalence 
    Boswell, Michael; Maimela, T.C.R. (Tshegofatso); Hameiri-Bowen, Dan; Riley, George; Malan, Albertus; Steyn, Nickietta; Nolutshungu, Nomonde; De Villiers, Talita R.; De Beer, Zelda; Mathabathe, John; Tshabalala, Khanyisile; Abdullah, Fareed; Ramlall, Rajiev; Heystek, Marthinus J.; Basu, Debashis; Rheeder, Paul; Ueckermann, Veronica; Van Hougenhouck-Tulleken, W.G. (Wesley) (AOSIS, 2023-01-27)
    BACKGROUND : HIV infection causes immune dysregulation affecting T-cell and monocyte function, which may alter coronavirus disease 2019 (COVID-19) pathophysiology. OBJECTIVES : We investigated the associations among ...
  • Cross-reactive neutralizing antibody responses elicited by SARS-CoV-2 501Y.V2 (B.1.351) 
    Moyo‑Gwete, Thandeka; Madzivhandila, Mashudu; Makhado, Zanele; Ayres, Frances; Mhlanga, Donald; Oosthuysen, Brent; Lambson, Bronwen E.; Kgagudi, Prudence; Tegally, Houriiyah; Iranzadeh, Arash; Doolabh, Deelan; Tyers, Lynn; Chinhoyi, Lionel R.; Mennen, Mathilda; Skelem, Sango; Marais, Gert; Wibmer, Constantinos K.; Bhiman, Jinal N.; Ueckermann, Veronica; Rossouw, Theresa M.; Boswell, Michael T.; De Oliveira, Tulio (Massachusetts Medical Society, 2021-06)
    No abstract available.
  • Decline in antibody responses to SARS-CoV-2 post-vaccination poses a risk to health care workers 
    Worsley, Catherine M.; Van der Mescht, Mieke Adri; Hoffmann, Daniel; Meyer, Pieter Willem Adriaan; Ueckermann, Veronica; Rossouw, Theresa M. (Elsevier, 2022-09)
    No abstract available.
  • Decreased severity of disease during the first global Omicron variant COVID-19 outbreak in a large hospital in Tshwane, South Africa 
    Abdullah, Fareed; Myers, J.; Basu, Debashis; Tintinger, Gregory; Ueckermann, Veronica; Mathebula, M.; Ramlall, R.; Spoor, S.; De Villiers, T.; Van der Walt, Z.; Cloete, Jeane; Soma-Pillay, Priya; Rheeder, Paul; Paruk, Fathima; Engelbrecht, Adel; Lalloo, Vidya; Myburg, M.; Kistan, J.; Van Hougenhouck-Tulleken, W.G. (Wesley); Boswell, Michael T.; Gray, G.; Welch, R.; Blumberg, Lucille Hellen; Jassat, W. (Elsevier, 2022-03)
    INTRODUCTION : The coronavirus disease 2019 (COVID-19) first reported in Wuhan, China in December 2019 is a global pandemic that is threatening the health and wellbeing of people worldwide. To date there have been more ...
  • Despite delayed kinetics, people living with HIV achieve equivalent antibody function after SARS-CoV-2 infection or vaccination 
    Motsoeneng, Boitumelo M.; Manamela, Nelia; Kaldine, Haajira; Kgagudi, Prudence; Hermanus, Tandile; Ayres, Frances; Makhado, Zanele; Moyo-Gwete, Thandeka; Van der Mescht, Mieke Adri; Abdullah, Fareed; Boswell, Michael; Ueckermann, Veronica; Rossouw, Theresa; Madhi, Shabir A.; Moore, Penny L.; Richardson, Simone I. (Frontiers Media, 2023-08-03)
    The kinetics of Fc-mediated functions following SARS-CoV-2 infection or vaccination in people living with HIV (PLWH) are not known. We compared SARS-CoV-2 spike-specific Fc functions, binding, and neutralization in ...
  • Detection of neutralizing antibodies in COVID-19 patients from Steve Biko Academic Hospital Complex : a pilot study 
    Kgatle, Mankgopo; Chalwe, Joseph Musonda; Van der Westhuizen, Donald; Xu, Shuting; Damane, Botle Precious; Mathebela, Precious; Ueckermann, Veronica; Mayaphi, Simnikiwe; Rodrigues, Hosana Gomes; Moura-Alves, Pedro; Ndlovu, Honest; Mzizi, Yonwaba; Zongo, Lusanda; Hairwadzi, Henry; Vorster, Mariza; Zeevaart, Jan Rijn; Sathekge, Mike Machaba (MDPI, 2023-07-03)
    A correlation between neutralization activity after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination and protection against coronavirus disease 2019 (COVID-19) has been demonstrated by several ...
  • Molecular epidemiology of Staphylococcus epidermidis implicated in catheter-related bloodstream infections at an academic hospital in Pretoria, South Africa 
    Ehlers, Marthie Magdaleen; Strasheim, Wilhelmina; Lowe, Michelle; Ueckermann, Veronica; Kock, Marleen M. (Frontiers Media, 2018-03)
    Staphylococcus epidermidis is one of the most prevalent pathogens implicated in catheter-related bloodstream infections (CRBSI) at an academic hospital in Pretoria, South Africa. Little is known about the clonality and ...
  • The prevalence of subclinical hypothyroidism among patients with diabetes mellitus at the Kalafong Hospital Diabetes Clinic : a cross-sectional study 
    Ueckermann, Veronica; Van Zyl, Danie G. (MedPharm Publications, 2013)
    OBJECTIVE: The purpose of this study was to determine the prevalence of subclinical hypothyroidism among patients with diabetes mellitus at the Kalafong Diabetes Clinic in Pretoria. DESIGN: Cross-sectional study. SETTING ...
  • SARS-CoV-2 501Y.V2 escapes neutralization by South African COVID-19 donor plasma 
    Wibmer, Constantinos Kurt; Ayres, Frances; Hermanus, Tandile; Madzivhandila, Mashudu; Kgagudi, Prudence; Oosthuysen, Brent; Lambson, Bronwen E.; De Oliveira, Tulio; Vermeulen, Marion; Van der Berg, Karin; Rossouw, Theresa M.; Boswell, Michael T.; Ueckermann, Veronica; Meiring, Susan; Von Gottberg, Anne; Cohen, Cheryl; Morris, Lynn; Bhiman, Jinal N.; Moore, Penny L. (Springer, 2021-04)
    SARS-CoV-2 501Y.V2 (B.1.351), a novel lineage of coronavirus causing COVID-19, contains substitutions in two immunodominant domains of the spike protein. Here, we show that pseudovirus expressing 501Y.V2 spike protein ...
  • SARS-CoV-2 Beta and Delta variants trigger Fc effector function with increased cross-reactivity 
    Richardson, Simone I.; Manamela, Nelia P.; Motsoeneng, Boitumelo M.; Kaldine, Haajira; Ayres, Frances; Makhado, Zanele; Mennen, Mathilda; Skelem, Sango; Williams, Noleen; Sullivan, Nancy J.; Misasi, John; Gray, Glenda G.; Bekker, Linda‑Gail; Ueckermann, Veronica; Rossouw, Theresa M.; Boswell, M.T.; Ntusi, Ntobeko A.B.; Burgers, Wendy A.; Moore, Penny L. (Cell Press, 2022-02-15)
    Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) variants of concern (VOCs) exhibit escape from neutralizing antibodies, causing concern about vaccine effectiveness. However, while non-neutralizing cytotoxic ...
  • SARS-CoV-2 Omicron triggers cross-reactive neutralization and Fc effector functions in previously vaccinated, but not unvaccinated, individuals 
    Richardson, Simone I.; Madzorera, Tatenda; Spencer, Holly; Manamela, Nelia P.; Van der Mescht, Mieke Adri; Lambson, Bronwen E.; Oosthuysen, Brent; Ayres, Frances; Makhado, Zanele; Moyo-Gwete, Thandeka; Mzindle, Nonkululeko; Motlou, Thopisang; Strydom, Amy; Mendes, Adriano; Tegally, Houriiyah; De Beer, Zelda; De Villiers, Talita Roma; Bodenstein, Annie; Van den Berg, Gretha; Venter, Marietjie; De Oliviera, Tulio; Ueckermann, Veronica; Rossouw, Theresa M.; Boswell, M.T.; Moore, Penny L. (Cell Press, 2022-03-24)
    The SARS-CoV-2 Omicron variant escapes neutralizing antibodies elicited by vaccines or infection. However, whether Omicron triggers cross-reactive humoral responses to other variants of concern (VOCs) remains unknown. We ...
  • Severe porphyric neuropathy – importance of screening for porphyria in Guillain-Barré syndrome 
    Schutte, Clara-Maria; Van der Meyden, C.H. (Kees); Van Niekerk, Linette; Kakaza, Mandisa; Van Coller, Riaan; Ueckermann, Veronica; Oosthuizen, Nicholette M. (Health and Medical Publishing Group, 2016-01)
    The hepatic porphyrias are a group of rare metabolic disorders, each of which is associated with a specific enzymatic alteration in the haem biosynthesis pathway. In South Africa (SA), a high incidence of variegate porphyria ...