Browsing Health Sciences by Title

Browsing Health Sciences by Title

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  • Optimisation of histocompatibility testing in living-donor renal transplantation 
    Kwofie, Luyanda Laura Illicia (University of Pretoria, 2018)
    The study addressed the development and evaluation of novel procedures for the rapid, reproducible and efficient measurement of T cell alloreactivity both pre- and post-transplantation, with the aim of optimizing donor/ ...
  • Optimising perioperative care for hip and knee arthroplasty in South Africa : a Delphi consensus study 
    Plenge, U.; Nortje, M.B.; Marais, L.C.; Jordaan, J.D.; Parker, R.; Van der Westhuizen, N.; Van der Merwe, J.F.; Marais, J.; September, W.V.; Davies, G.L.; Pretorius, T.; Solomon, C.; Ryan, P.; Torborg, A.M.; Farina, Z.; Smit, R.; Cairns, C.; Shanahan, H.; Sombili, Simon; Mazibuko, A.N. (Andile); Hobbs, H.R.; Porrill, O.S.; Timothy, N.E.; Siebritz, R.E.; Van der Westhuizen, C.; Troskie, A.J.; Blake, C.A.; Gray, L.A.; Munting, T.W.; Steinhaus, H.K.S.; Rowe, P.; Van der Walt, J.G.; Noordien, R. Isaacs; Theron, A.; Biccard, Bruce McIure (BioMed Central, 2018-05-09)
    BACKGROUND : A structured approach to perioperative patient management based on an enhanced recovery pathway protocol facilitates early recovery and reduces morbidity in high income countries. However, in low- and middle-income ...
  • Optimising the efficacy of clofazimine against biofilm-encased Mycobacterium tuberculosis 
    Mashele, Sizeka Aubrey (University of Pretoria, 2020)
    Background: The chemotherapy of tuberculosis (TB) patients is administered for a six to nine- month period consisting of an intensive phase during the first two months with four primary anti- TB drugs, rifampicin (RMP), ...
  • Optimising the International Classification of Diseases to identify the maternal condition in the case of perinatal death 
    Allanson, Emma R.; Tunçalp, Ozge; Gardosi, Jason; Pattinson, Robert Clive; Francis, Andre; Vogel, Joshua P.; Erwich, Jan Jaap H.M.; Flenady, Vicki J.; Frøen, J. Frederik; Neilson, James; Quach, Amanda; Chou, Doris; Mathai, Matthews; Say, Lale; Gülmezoglu, A. Metin (Wiley, 2016-11)
    OBJECTIVE : The WHO application of the tenth edition of the International Classification of Diseases (ICD-10) to deaths during the perinatal period (ICD Perinatal Mortality, ICD-PM) captures the essential characteristics ...
  • An optimistic vision for biosciences in South Africa : reply to Thaldar et al. (2019) 
    Pepper, Michael Sean; Dandara, Collet; De vries, Jantina; Dhai, Amaboo; Labuschaigne, Melodie; Mnyongani, Freddy; Moodley, Keymanthri; Olckers, Antonel; Pope, Anne; Ramesar, Ray; Ramsay, Michele; Towers, Wayne (Academy of Science of South Africa, 2019)
    Our reply to Thaldar et al.’s response to the ASSAf report on human genetics and genomics focuses on two elements of the Report which they highlight, namely ubuntu and sovereignty. The lack of engagement with other issues ...
  • Optimization of critical hairpin features allows miRNA-based gene knockdown upon single-copy transduction 
    Myburgh, Renier; Cherpin, Ophélie; Schlaepfer, Erika; Rehrauer, Hubert; Speck, Roberto F.; Krause, Karl-Heinz; Salmon, Patrick (Nature Publishing Group, 2014)
    Gene knockdown using micro RNA (miRNA)-based vector constructs is likely to become a prominent gene therapy approach. It was the aim of this study to improve the efficiency of gene knockdown through optimizing the structure ...
  • Optimization of techniques required for somatic cell nuclear transfer using a mouse model 
    Gouveia, Chantel (University of Pretoria, 2018)
    Introduction: Somatic cell nuclear transfer (SCNT) is the removal (enucleation) of chromosomes from a metaphase II oocyte, followed by the transfer and fusion of a donor somatic cell to the enucleated oocyte (cytoplast). ...
  • Optimizing adherence in HIV prevention product trials : development and psychometric evaluation of simple tools for screening and adherence counseling 
    Tolley, Elizabeth E.; Guthrie, Kate Morrow.; Zissette, Seth; Fava, Joseph L.; Gill, Katherine; Louw, Cheryl; Kotze, Philip; Reddy, Krishnaveni; MacQueen, Kathleen (Public Library of Science, 2018-04)
    BACKGROUND: Low adherence in recent HIV prevention clinical trials highlights the need to better understand, measure, and support product use within clinical trials. Conventional self-reported adherence instruments within ...
  • Optimizing mycobacterial culture in smear-negative, human immunodeficiency virus-infected Tuberculosis cases 
    Ismail, Nazir Ahmed; Said, H.M. (Halima Mohammed); Pinini, Z.; Omar, Shaheed Vally; Beyers, N.; Naidoo, P. (Public Library of Science, 2015-11-06)
    INTRODUCTION Tuberculosis (TB) is a significant public health problem and the diagnosis in human immunodeficiency virus (HIV)—infected individuals is challenging. The use of mycobacterial culture remains an important ...
  • Oral and oropharyngeal impalement injury in pediatric patients - focus on rural environment 
    Syebele, Kabunda; Van Straten, Cornelia; Chidinyane, Lebaka (Elsevier, 2012-08)
    OBJECTIVE : This article describes a case series of oral and oropharyngeal impalement injuries in pediatric patients and highlights the peculiar etiological role of the rural environment. STUDY DESIGN : The records of nine ...
  • Oral brincidofovir therapy for monkeypox outbreak : a focused review on the therapeutic potential, clinical studies, patent literature, and prospects 
    Imran, Mohd.; Alshammari, Mohammed Kanan; Arora, Mandeep Kumar; Dubey, Amit Kumar; Das, Sabya Sachi; Kamal, Mehnaz; Alqahtani, Abdulaziz Saad Abdulrahman; Sahloly, Mohammed Ahmed Yahya; Alshammari, Ahmed Hammad; Alhomam, Hessah Mohammed; Mahzari, Aeshah Mousa; Abida; Rabaan, Ali A.; Dzinamarira, Tafadzwa (MDPI, 2023-02)
    The monkeypox disease (MPX) outbreak of 2022 has been reported in more than one hundred countries and is becoming a global concern. Unfortunately, only a few treatments, such as tecovirimat (TCV), are available against ...
  • Oral complications of HIV disease in children in the post 1998 era of HAART : a descriptive cross sectional study of prevalences, retrospective and clinical 
    Mthethwa, S.R.; Mmutlana, M.I.; Booysen, A.; Chabikuli, Nzapfurundi O. (South African Dental Association, 2015-09)
    INTRODUCTION : The administration of HAART* has changed the frequency and character of the oral complications of HIV disease. AIMS AND OBJECTIVES : This study describes and compares the incidence and status of dental ...
  • Oral exposure to cadmium and mercury alone and in combination causes damage to the lung tissue of Sprague-Dawley rats 
    Koopsamy Naidoo, Sirasha Venketsamy; Bester, Megan Jean; Arbi, Sandra; Venter, Chantelle; Dhanraj, Priyanka; Oberholzer, Hester Magdalena (Elsevier, 2019-07)
    Environmental presence and human exposure to heavy metals in air and cigarette smoke has led to a worldwide increase in respiratory disease. The effects of oral exposure to heavy metals in liver and kidney structure and ...
  • Oral health and subjective psychological well-being among South African adults : findings from a national household survey 
    Ayo-Yusuf, Olalekan Abdulwahab; Motloba, P.; Ayo-Yusuf, Imade J. (South African Dental Association, 2015-11)
    OBJECTIVE : To determine the association between oral health and socioeconomic status with subjective psychological well-being. METHODS : An interviewer-administered questionnaire was conducted during 2011 on a nationally ...
  • Oral health in general practice 
    Van Heerden, Willem Francois Petrus (Medpharm Publishers, 2007-09)
  • Oral health knowledge, attitudes and practices among school teachers in Tshwane district, South Africa 
    Mfolo, Tshepiso; Madiba, Thomas Khomotjo; Bhayat, Ahmed (South African Dental Association, 2021-06)
    INTRODUCTION : Teachers are perceived as role models and studies have shown that they can enhance the oral health behaviour of young children. AIMS AND OBJECTIVES : To assess the oral health (OH) knowledge, attitudes and ...
  • Oral malodour 
    Van Zyl, Andre W.; Fourie, Jeanine; Van Heerden, Willem Francois Petrus (South African Academy of Family Practice/Primary Care, 2011-07)
    Oral malodour may affect up to three billion people worldwide, with millions of dollars spent on treatment. Halitosis is often used synonymously, but oral malodour is the preferred term for any bad breath emanating from ...
  • Oral manifestations of viral infections 
    Van Heerden, Willem Francois Petrus (Medpharm Publishers, 2006-09)
    Examination of the oral cavity is an integral part of every clinical examination. The clinical presentation of various viral conditions is discussed in this article and will provide the family practitioner with an up to ...
  • Oral medicine case book 40 : Oral histoplasmosis 
    Stander, S.; Molatjana, R.E.; Dreyer, W.P.; Marnewick, J.C. (Johan); Afrogheh, A.; Schubert, P.T.; Hille, J. (South African Dental Association, 2012-06)
    No abstract available.
  • Oral medicine case book 59 : Syphilis of the oral mucosa 
    Bunn, Belinda Kathleen; Marnewick, J.C. (Johan); Van Zyl, Andre W.; Van Heerden, Willem Francois Petrus (South African Dental Association, 2014-05)
    A 35-year-old male patient presented to the Oral Medicine Clinic complaining of painful oral ulcers of six weeks duration. The patient was a non-smoker and did not report any additional medical history of clinical significance.