UPSpace Home
→
Veterinary Science
→
Veterinary Tropical Diseases
→
Research Articles (Veterinary Tropical Diseases)
→
Browsing Research Articles (Veterinary Tropical Diseases) by UP Author

Browsing Research Articles (Veterinary Tropical Diseases) by UP Author "Thema, Nontobeko"

Now showing items 1-4 of 4

Cellular immune responses induced in vitro by Ehrlichia ruminantium secreted proteins and identification of vaccine candidate peptides

Thema, Nontobeko; Pretorius, Alri; Tshilwane, Selaelo Ivy; Liebenberg, Junita; Steyn, Helena; Van Kleef, Mirinda (AOSIS OpenJournals, 2016-08-30)

Secreted proteins are reported to induce cell-mediated immunity characterised by the production of interferon-gamma (IFN)-γ. In this study three open reading frames (ORFs) (Erum8060, Erum7760, Erum5000) encoding secreted ...
Ehrlichia ruminantium antigens and peptides induce cytotoxic T cell responses in vitro

Thema, Nontobeko; Tshilwane, Selaelo Ivy; Son, L.; Smith, R.M.; Faber, Frederika E.; Steyn, Helena C.; Van Kleef, Mirinda; Liebenberg, Junita; Pretorius, Alri (Elsevier, 2019-01)

Since CD8+ T cells play an important role in resistance to infection with heartwater, effective vaccines against this disease will likely require identification of antigens that contain CD8+ T cell epitopes responsible for ...
Identification and characterisation of conserved epitopes of E. ruminantium that activate Th1 CD4+ T cells : towards the development of a multi-epitope vaccine

Thema, Nontobeko; Tshilwane, Selaelo Ivy; Pretorius, Alri; Son, L.; Smith, R.M.; Steyn, Helena C.; Liebenberg, Junita; Van Kleef, Mirinda (Elsevier, 2019-03)

Several studies have shown that cytotoxic T lymphocytes (CTL) require CD4 + Th1 epitopes to generate strong immune responses to intracellular pathogens. However, not much is known about Ehrlichia ruminantium epitopes, ...
A multi-epitope DNA vaccine co-administered with monophosphoryl lipid A adjuvant provides protection against tick transmitted Ehrlichia ruminantium in sheep

Tshilwane, Selaelo Ivy; Thema, Nontobeko; Steyn, Helena C.; Van Kleef, Mirinda; Pretorius, Alri (Elsevier, 2019-07)

Previously, a heartwater experimental DNA vaccine provided 100% protection following laboratory challenge with Ehrlichia ruminantium administered by needle but not against an E. ruminantium tick challenge in the field. A ...

Now showing items 1-4 of 4

Search UPSpace

Browse

All of UPSpace
This Collection
- Issue Date
- Authors
- Titles
- Subjects
- Supervisor
- UP Author
- UP Postgraduate
- Type

Browsing Research Articles (Veterinary Tropical Diseases) by UP Author "Thema, Nontobeko"

Browsing Research Articles (Veterinary Tropical Diseases) by UP Author "Thema, Nontobeko"

Search UPSpace

Browse

All of UPSpace

This Collection

My Account

UPSpace Workspace