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Browsing Research Articles (Veterinary Tropical Diseases) by Author "Hackeng, Tilman M."

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Molecular basis of anticoagulant and anticomplement activity of the tick salivary protein Salp14 and its homologs

Denisov, Stepan S.; Ippel, Johannes H.; Castoldi, Elisabetta; Mans, Ben J. (Barend Johannes); Hackeng, Tilman M.; Dijkgraaf, Ingrid (American Society for Biochemistry and Molecular Biology, 2021)

During feeding, a tick’s mouthpart penetrates the host’s skin and damages tissues and small blood vessels, triggering the extrinsic coagulation and lectin complement pathways. To elude these defense mechanisms, ticks secrete ...

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