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Browsing Research Articles (University of Pretoria) by Subject "P-Glycoprotein"

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Solamargine, a bioactive steroidal alkaloid isolated from Solanum aculeastrum induces non-selective cytotoxicity and P-glycoprotein inhibition

Burger, Trevor; Mokoka, Tsholofelo; Fouche, Gerda; Steenkamp, Paul; Steenkamp, Vanessa; Cordier, Werner (BioMed Central, 2018-05-02)

BACKGROUND : Solanum aculeastrum fruits are used by some cancer sufferers as a form of alternative treatment. Scientific literature is scarce concerning its anticancer activity, and thus the aim of the study was to assess ...

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