Browsing Research Articles (University of Pretoria) by Author "Saba, Adebowale Benard"

Browsing Research Articles (University of Pretoria) by Author "Saba, Adebowale Benard"

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  • Antihypertensive action of Launaea taraxacifolia and its molecular mechanism of action 
    Oyagbemi, Ademola Adetokunbo; Hassan, Fasilat Oluwakemi; Ajibade, Temitayo Olabisi; Ola-Davies, Olufunke Eunice; Omobowale, Temidayo Olutayo; Ajani, Olumide Samuel; Jarikre, Theophilus Aghogho; Soetan, Kehinde Olugboyega; Saba, Adebowale Benard; Adedapo, Adeolu Alex; Aro, Abimbola Obemisola; Oyeyemi, Matthew Olugbenga; Emikpe, Benjamin Obukowho; Nkadimeng, Sanah Malomile; McGaw, Lyndy Joy; Kayoka-Kabongo, Prudence Ngalula; Yakubu, Momoh Audu; Oguntibeju, Oluwafemi Omoniyi (University of Karachi, 2022-11)
    Launaea taraxacifolia has been traditionally used for the management of conditions such as cardiovascular, respiratory, and metabolic diseases. High blood pressure was established by oral administration of L-Nitro ...
  • Antihypertensive power of Naringenin is mediated via attenuation of mineralocorticoid receptor (MCR)/ angiotensin converting enzyme (ACE)/ kidney injury molecule (Kim-1) signaling pathway 
    Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Adejumobi, Olumuyiwa Abiola; Owolabi, Abiodun Mary; Ogunpolu, Blessing Seun; Falayi, Olufunke Olubunmi; Hassan, Fasilat Oluwakemi; Ogunmiluyi, Iyanuoluwa Omolola; Asenuga, Ebunoluwa Racheal; Ola-Davies, Olufunke Eunice; Soetan, Kehinde Olugboyega; Saba, Adebowale Benard; Adedapo, Adeolu Alex; Nkadimeng, Sanah Malomile; McGaw, Lyndy Joy; Oguntibeju, Oluwafemi Omoniyi; Yakubu, Momoh Audu (Elsevier, 2020-08)
    Please read abstract in the article.
  • Clofibrate, a peroxisome proliferator–activated receptor-alpha (PPARα) agonist, and Its molecular mechanisms of action against sodium fluoride–induced toxicity 
    Oyagbemi, Ademola Adetokunbo; Adejumobi, Olumuyiwa Abiola; Jarikre, Theophilus Aghogho; Ajani, Olumide Samuel; Asenuga Ebunoluwa Racheal; Gbadamosi, Idayat Titilayo; Adedapo, Aduragbenro Deborah A.; Aro, Abimbola O.; Ogunpolu, Blessing Seun; Hassan, Fasilat Oluwakemi; Falayi, Olufunke Olubunmi; Ogunmiluyi, Iyanuoluwa Omolola; Omobowale, Temidayo Olutayo; Arojojoye, Oluwatosin Adetola; Ola-Davies, Olufunke Eunice; Saba, Adebowale Benard; Adedapo, Adeolu Alex; Emikpe, Benjamin Obukowho; Oyeyemi, Matthew Olugbenga; Nkadimeng, Sanah Malomile; McGaw, Lyndy Joy; Kayoka-Kabongo, Prudence Ngalula; Oguntibeju, Oluwafemi Omoniyi; Yakubu, Momoh Audu (Springer, 2022-03)
    Sodium fluoride (NaF) is one of the neglected environmental pollutants. It is ubiquitously found in the soil, water, and environment. Interestingly, fluoride has been extensively utilized for prevention of dental caries ...
  • Clofibrate, a PPAR-alpha agonist, abrogates sodium fluoride-induced neuroinflammation, oxidative stress, and motor incoordination via modulation of GFAP/Iba-1/anti-calbindin signaling pathways 
    Oyagbemi, Ademola A.; Adebiyi, Olamide E.; Adigun, Kabirat O.; Ogunpolu, Blessing Seun; Falayi, Olufunke Olubunmi; Hassan, Fasilat Oluwakemi; Folarin, Oluwabusayo R,; Adebayo, Adedeji K.; Adejumobi, Olumuyiwa Abiola; Asenuga, Ebunoluwa R.; Ola-Davies, Olufunke Eunice; Omobowale, Temidayo Olutayo; Olopade, James O.; Saba, Adebowale Benard; Adedapo, Adeolu Alex; Nkadimeng, Sanah Malomile; McGaw, Lyndy Joy; Oguntibeju, Oluwafemi Omoniyi; Yakubu, Momoh Audu (Wiley, 2020-02)
    Please read abstract in the article.
  • L-arginine and lisinopril supplementation protects against sodium fluoride–induced nephrotoxicity and hypertension by suppressing mineralocorticoid receptor and angiotensin-converting enzyme 3 activity 
    Ajibade, Temitayo Olabisi; Awodele, Olusola Adedayo; Tijani, Monsuru Oladunjoye; Adejumobi, Olumuyiwa Abiola; Adetona, Moses Olusola; Oyagbemi, Ademola Adetokunbo; Adedapo, Aduragbenro Deborah A.; Omobowale, Temidayo Olutayo; Aro, Abimbola O.; Ola-Davies, Olufunke Eunice; Saba, Adebowale Benard; Adedapo, Adeolu Alex; Nkadimeng, Sanah Malomile; McGaw, Lyndy Joy; Kayoka-Kabongo, Prudence Ngalula; Oguntibeju, Oluwafemi Omoniyi; Yakubu, Momoh Audu (Springer, 2023-02)
    Sodium fluoride (NaF) is one of the neglected environmental toxicants that has continued to silently cause toxicity to both humans and animals. NaF is universally present in water, soil, and atmosphere. The persistent and ...
  • Novel antihypertensive action of rutin is mediated via inhibition of angiotensin converting enzyme/mineralocorticoid receptor/angiotensin 2 type 1 receptor (ATR1) signaling pathways in uninephrectomized hypertensive rats 
    Oyagbemi, Ademola Adetokunbo; Bolaji-Alabi, Foluso Bolawaye; Ajibade, Temitayo Olabisi; Adejumobi, Olumuyiwa Abiola; Ajani, Olumide Samuel; Jarikre, Theophilus Aghogho; Omobowale, Temidayo Olutayo; Ola-Davies, Olufunke Eunice; Soetan, Kehinde Olugboyega; Aro, Abimbola Obemisola; Emikpe, Benjamin Obukowho; Saba, Adebowale Benard; Adedapo, Adeolu Alex; Oyeyemi, Matthew Olugbenga; Nkadimeng, Sanah Malomile; Kayoka-Kabongo, Prudence Ngalula; McGaw, Lyndy Joy; Oguntibeju, Oluwafemi Omoniyi; Yakubu, Momoh Audu (Wiley, 2020-12)
    Hypertension is the most common cardiovascular disease that affects approximately 26% of adult population, worldwide. Rutin is one of the important flavonoids that is consumed in the daily diet, and found in many food ...
  • Potential health benefits of zinc supplementation for the management of COVID-19 pandemic 
    Oyagbemi, Ademola A.; Ajibade, Temitayo Olabisi; Aboua, Yapo Guillaume; Gbadamosi, Idayat Titilayo; Adedapo, Aduragbenro Deborah A.; Aro, A.O. (Abimbola); Adejumobi, Olumuyiwa Abiola; Thamahane-Katengua, Emma; Omobowale, Temidayo Olutayo; Falayi, Olufunke Olubunmi; Oyagbemi, Taiwo Olaide; Ogunpolu, Blessing Seun; Hassan, Fasilat Oluwakemi; Ogunmiluyi, Iyanuoluwa Omolola; Ola-Davies, Olufunke Eunice; Saba, Adebowale Benard; Adedapo, Adeolu Alex; Nkadimeng, Sanah Malomile; McGaw, Lyndy Joy; Kayoka-Kabongo, Prudence Ngalula; Oguntibeju, Oluwafemi Omoniyi; Yakubu, Momoh Audu (Wiley, 2021-02)
    The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the etiological agent for the Coronavirus Disease 2019 (COVID-19). The COVID-19 pandemic has created unimaginable and unprecedented global health crisis. ...
  • The therapeutic potential of the novel angiotensin-converting enzyme 2 in the treatment of coronavirus disease-19 
    Oyagbem, Ademola Adetokunbo; Ajibade, Temitayo Olabisi; Aboua, Yapo Guillaume; Gbadamosi, Idayat Titilayo; Adedapo, Aduragbenro Deborah A.; Aro, Abimbola Obemisola; Adejumobi, Olumuyiwa Abiola; Thamahane-Katengua, Emma; Omobowale, Temidayo Olutayo; Falayi, Olufunke Olubunmi; Oyagbemi, Taiwo Olaide; Ogunpolu, Blessing Seun; Hassan, Fasilat Oluwakemi; Ogunmiluyi, Iyanuoluwa Omolola; Ola-Davies, Olufunke Eunice; Saba, Adebowale Benard; Adedapo, Adeolu Alex; Nkadimeng, Sanah Malomile; McGaw, Lyndy Joy; Kayoka-Kabongo, Prudence Ngalula; Yakubu, Momoh Audu; Oguntibeju, Oluwafemi Omoniyi (Veterinary World, 2021-10-14)
    Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the etiological agent of coronavirus disease 2019 (COVID-19). This virus has become a global pandemic with unprecedented mortality and morbidity along with ...