dc.contributor.author |
Wessels, Quenton
|
|
dc.contributor.author |
Pretorius, Etheresia
|
|
dc.date.accessioned |
2016-09-02T06:48:15Z |
|
dc.date.available |
2016-09-02T06:48:15Z |
|
dc.date.issued |
2015-08 |
|
dc.description.abstract |
Burn wound care today has a primary objective of temporary or permanent wound closure.
Commercially available engineered alternative tissues have become a valuable adjunct to
the treatment of burn injuries. Their constituents can be biological, alloplastic or a
combination of both. Here the authors describe the aspects of the development of a
siloxane epidermis for a collagen-glycosaminoglycan and for nylon-based artificial skin
replacement products. A method to fabricate an ultra-thin epidermal equivalent is
described. Pores, to allow the escape of wound exudate, were punched and a tri-filament
nylon mesh or collagen scaffold was imbedded and silicone polymerisation followed at
120°C for 5 minutes. The ultra-structure of these bilaminates was assessed through scanning
electron microscopy. An ultra-thin biomedical grade siloxane film was reliably created
through precision coating on a pre-treated polyethylene terephthalate carrier. |
en_ZA |
dc.description.department |
Anatomy |
en_ZA |
dc.description.librarian |
hb2016 |
en_ZA |
dc.description.sponsorship |
Southern Group of Companies, Gauteng, South Africa. |
en_ZA |
dc.description.uri |
http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1742-481X |
en_ZA |
dc.identifier.citation |
Wessels, Q & Pretorius, E 2015, 'Development and ultra-structure of an ultra-thin silicone epidermis of bioengineered alternative tissue', International Wound Journal, vol. 12, no. 4, pp. 428-431 |
en_ZA |
dc.identifier.issn |
1742-4801(print) |
|
dc.identifier.issn |
1742-481X (online) |
|
dc.identifier.other |
10.1111/iwj.12126 |
|
dc.identifier.uri |
http://hdl.handle.net/2263/56583 |
|
dc.language.iso |
en |
en_ZA |
dc.publisher |
Wiley |
en_ZA |
dc.rights |
© 2013 The Authors. International Wound Journal © 2013 Medicalhelplines.com Inc and John Wiley & Sons Ltd. This is the pre-peer reviewed version of the following article : Development and ultra-structure of an ultra-thin silicone epidermis of bioengineered alternative tissue, International Wound Journal, vol. 12, no. 4, pp. 428-431, 2015. doi : 10.1111/iwj.12126. The definite version is available at : http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1742-481X. |
en_ZA |
dc.subject |
Bioengineered alternative tissue |
en_ZA |
dc.subject |
Burn wound |
en_ZA |
dc.subject |
Siloxane epidermis |
en_ZA |
dc.subject |
Temporary skin substitute |
en_ZA |
dc.subject |
Ultra-thin membrane |
en_ZA |
dc.subject.other |
Health sciences article SDG-03 |
|
dc.subject.other |
SDG-03: Good health and well-being |
|
dc.subject.other |
Health sciences article SDG-17 |
|
dc.subject.other |
SDG-17: Partnerships for the goals |
|
dc.title |
Development and ultra-structure of an ultra-thin silicone epidermis of bioengineered alternative tissue |
en_ZA |
dc.type |
Postprint Article |
en_ZA |