dc.contributor.author |
Kunert, Karl J.
|
|
dc.contributor.author |
Van Wyk, Stefan George
|
|
dc.contributor.author |
Cullis, C.A. (Christoper Ashley)
|
|
dc.contributor.author |
Vorster, Barend Juan
|
|
dc.contributor.author |
Foyer, Christine H.
|
|
dc.date.accessioned |
2015-08-24T05:17:47Z |
|
dc.date.available |
2015-08-24T05:17:47Z |
|
dc.date.issued |
2015-06 |
|
dc.description.abstract |
Phytocystatins are a well-characterized class of naturally-occurring protease inhibitors that
function by preventing the catalysis of papain-like cysteine proteases. The action of cystatins
in biotic stress resistance has been intensively studied but relatively little is known about their
functions in plant growth and defence responses to abiotic stresses, such as drought. Extreme
weather events such as drought and flooding will become more frequent as a result of climate
change. The concepts that changes in cellular protein content and composition are required for
acclimation to different abiotic stresses and that these adjustments are achieved through regulation of proteolysis are widely accepted. However, the nature and regulation of the
protein turnover machinery that underpins essential stress-induced cellular re-structuring
remains poorly characterised. Cysteine proteases are intrinsic to the genetic programs that
underpin developmental senescence, but their functions in stress-induced senescence are
poorly defined. While much remains uncertain regarding the individual cysteine protease
targets of endogenous cystatins and their precise functions in the regulation of physiological
processes are largely unknown, current evidence suggests that manipulation of cysteine
protease activities by engineered cystatin expression might be used for to improve the
resilience and quality of crop plants in the face of climate change. |
en_ZA |
dc.description.embargo |
2016-06-30 |
en_ZA |
dc.description.librarian |
hb2015 |
en_ZA |
dc.description.sponsorship |
This work was funded by FP7-PIRSES-GA-2008-230830 (LEGIM) and PIIF-GA-2011-
299347 (Soylife; K.K.). This work was further funded by the International Foundation of
Science (IFS grant C/5151-1), the NRF Thuthuka program (B.J.V.) and the NRF Incentive
Funding program for rated researchers (K.K.). The funding received from the Genomic
Research Institute, University of Pretoria, is hereby also acknowledged. S.G.V.W. thank the NRF/DST in South Africa for bursaries. |
en_ZA |
dc.description.uri |
http://jxb.oxfordjournals.org |
en_ZA |
dc.identifier.citation |
Kunert, KJ, Van Wyk, SG, Cullis, CA, Vorster, BJ & Foyer, CH 2015, 'Potential use of phytocystatins in crop improvement, with a particular focus on legumes', Journal of Experimental Botany, vol. 66, no. 12, pp. 3559-3570. |
en_ZA |
dc.identifier.issn |
0022-0957 (print) |
|
dc.identifier.issn |
1460-2431 (online) |
|
dc.identifier.other |
10.1093/jxb/erv211 |
|
dc.identifier.uri |
http://hdl.handle.net/2263/49447 |
|
dc.language.iso |
en |
en_ZA |
dc.publisher |
Oxford University Press |
en_ZA |
dc.rights |
© The Author 2015. Published by Oxford University Press on behalf of the Society for Experimental Biology. All rights reserved. This is a pre-copy-editing, author-produced PDF of an article accepted for publication in Journal of Experimental Botany following peer review. The definitive publisher-authenticated version is : Potential use of phytocystatins in crop improvement, with a particular focus on legumes, Journal of Experimental Botany, vol. 66, no. 12, pp. 3559-3570, 2015. doi : 10.1093/jxb/erv211. Journal of Experimental Botany is available online at : http://jxb.oxfordjournals.org. |
en_ZA |
dc.subject |
Cystatin |
en_ZA |
dc.subject |
Senescence |
en_ZA |
dc.subject |
Protein degradation |
en_ZA |
dc.subject |
Soybean |
en_ZA |
dc.subject |
Drought |
en_ZA |
dc.subject |
Chilling |
en_ZA |
dc.subject |
Stress tolerance |
en_ZA |
dc.title |
Potential use of phytocystatins in crop improvement, with a particular focus on legumes |
en_ZA |
dc.type |
Postprint Article |
en_ZA |