dc.contributor.author |
Caetano, M.C.
|
|
dc.contributor.author |
Afonso, F.
|
|
dc.contributor.author |
Ribeiro, R.
|
|
dc.contributor.author |
Fonseca, A.P.
|
|
dc.contributor.author |
Abernethy, D.A. (Darrell)
|
|
dc.contributor.author |
Boinas, F.
|
|
dc.date.accessioned |
2014-10-08T07:33:49Z |
|
dc.date.issued |
2016-02 |
|
dc.description.abstract |
Bovine brucellosis due to Brucella abortus infection causes significant reproduc-tive and production losses in cattle and is a
major zoonosis. Eradication of this disease has proved difficult to achieve in Portugal where it still occurs in some regions
despite an ongoing national eradication programme. In 2004, the Alent-ejo region, a major cattle producing area, reported
one of the highest levels of bovine brucellosis in the country, especially in one divisional area. In that area, bovine brucellosis
was particularly problematic in a holding of ten herds, the largest extensive cattle unit in the country, which remained infected
despite an extensive test-and-slaughter programme and depopulation of five herds. A 5-year programme of RB51 vaccination
with biannual test-and-slaughter was thus implemented in 2004. The apparent animal seroprevalence decreased from 19%
(646/3,400) to 3% (88/2930) on the third herd-level test and remained below 0.8% (27/3324) after the fourth test. After the
tenth test, the holding had a prevalence of 0.1% (2/2332) and only one herd remained positive with a within-herd prevalence
of 1.1% (2/177). The results were compared to all other herds (n = 10) in the divisional area that were also persistently
infected but were subject only to test-and-slaughter before being depopulated. In these herds, the strategy of test-andslaughter
did not reduce the prevalence, which remained significantly higher than the vaccinated group (median = 0.48% and
8.5% in vaccinated versus non-vaccinated herds; Wilcoxon rank sum test; P < 0.01). The success of this pilot programme in
continental Portugal pro-vided a valuable case study to the official veterinary services by illustrating the value of RB51
vaccination with parallel testing and improved biosecurity as a comprehensive and sustainable strategy for bovine brucellosis
control in persis-tently infected herds. |
en_US |
dc.description.embargo |
2015-04-30 |
|
dc.description.librarian |
hb2014 |
en_US |
dc.description.uri |
http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1865-1682 |
en_US |
dc.identifier.citation |
Caetano, MC, Afonso, F, Ribeiro, R, Fonseca, AP, Abernethy, DA & Boinas, F 2016, 'Control of bovine brucellosis from persistently infected holdings using RB51 vaccination with test-and-slaughter : a comparative case report from a high incidence area in Portugal', Transboundary and Emerging Diseases, vol. 63, no. 1, pp. e39–e47. |
en_US |
dc.identifier.issn |
1865-1674 (print) |
|
dc.identifier.issn |
1865-1682 (online) |
|
dc.identifier.other |
10.1111/tbed.12228 |
|
dc.identifier.other |
21638520700 |
|
dc.identifier.uri |
http://hdl.handle.net/2263/42295 |
|
dc.language.iso |
en |
en_US |
dc.publisher |
Wiley |
en_US |
dc.relation.requires |
Adobe Acrobat Reader |
en |
dc.rights |
© 2014 Blackwell Verlag GmbH. This is the pre-peer reviewed version of the following article : Control of Bovine Brucellosis from Persistently Infected Holdings Using RB51 Vaccination with Test-and-Slaughter: A Comparative Case Report from a High Incidence Area in Portugal, Transboundary and Emerging Diseases, vol. 63, no. 1, pp. e39–e47, 2016, doi : 10.1111/tbed.12228. The definite version is available at : http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1865-1682. |
en_US |
dc.subject |
Bovine brucellosis |
en_US |
dc.subject |
Eradication programme |
en_US |
dc.subject |
Portugal |
en_US |
dc.subject |
Test-and-slaughter |
en_US |
dc.subject |
Stamping-out |
en_US |
dc.subject |
RB51 vaccination |
en_US |
dc.title |
Control of bovine brucellosis from persistently infected holdings using RB51 vaccination with test-and-slaughter : a comparative case report from a high incidence area in Portugal |
en_US |
dc.type |
Postprint Article |
en_US |