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Browsing Health Sciences by UP Author "Pheiffer, Carmen"
Now showing items 1-14 of 14
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Masete, Matladi Innocent; Dias, Stephanie; Malaza, Nompumelelo; Adam, Sumaiya; Pheiffer, Carmen (Frontiers Media S.A., 2022-07-25)Maternal diabetes is associated with pregnancy complications and poses a serious health risk to both mother and child. Growing evidence suggests that pregnancy complications are more frequent and severe in pregnant women ...
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Pheiffer, Carmen; Dias, Stephanie; Mendham, Amy E.; Jack, Babalwa; Willmer, Tarryn; Eshibona, Nasr; Bendou, Hocine; Pretorius, Ashley; Goedecke, Julia H. (Nature Research, 2022-11-01)The mechanisms that underlie exercise-induced adaptations in adipose tissue have not been elucidated, yet, accumulating studies suggest an important role for microRNAs (miRNAs). This study aimed to investigate miRNA ...
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Malaza, Nompumelelo; Pheiffer, Carmen; Dias, S.; Adam, Sumaiya (Health and Medical Publishing Group, 2023-06)BACKGROUND : Diabetes and obesity in pregnancy have been associated with increased rates of adverse maternal and neonatal outcomes compared with women with normoglycaemia and normal weight. OBJECTIVE : To investigate the ...
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Adam, Sumaiya; Pheiffer, Carmen; Dias, Stephanie; Hlongwane, T.M.A.G. (Tsakane); Vannevel, Valerie; Soma-Pillay, Priya; Abdullah, Fareed (Frontiers Media SA, 2022-07-13)Despite many advances in medicine we are still faced with emerging pathogens. Pregnant women have been disproportionately affected by previous coronavirus outbreaks. The COVID-19 pandemic has not affected pregnant women ...
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Jack, Babalwa Unice; Ramharack, Pritika; Malherbe, Christiaan; Gabuza, Kwazi; Joubert, Elizabeth; Pheiffer, Carmen (MDPI, 2023-02)Previously, we reported that a crude polyphenol-enriched fraction of Cyclopia intermedia (CPEF), a plant consumed as the herbal tea, commonly known as honeybush, reduced lipid content in 3T3-L1 adipocytes and inhibited ...
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Abrahams, Yoonus; Willmer, Tarryn; Patel, Oelfah; Samodien, Ebrahim; Muller, Christo J.F.; Windvogel, Shantal; Johnson, Rabia; Pheiffer, Carmen (Elsevier, 2023-11)Previously we reported that a high fat, high sugar (HFHS) diet induced adiposity, hyperinsulinaemia, hyperleptinaemia, hypertriglyceridaemia and increased liver mass in male Wistar rats. In the present study, the mechanisms ...
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Riedel, Sylvia; Pheiffer, Carmen; Johnson, Rabia; Louw, Johan; Muller, Christo J. F. (Frontiers Media S.A., 2022-01-25)Noncommunicable diseases, such as type 2 diabetes (T2D), place a burden on healthcare systems worldwide. The rising prevalence of obesity, a major risk factor for T2D, is mainly attributed to the adoption of Westernized ...
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Nyawo, Thembeka A.; Pheiffer, Carmen; Mazibuko-Mbeje, Sithandiwe E.; Mthembu, Sinenhlanhla X.H.; Nyambuya, Tawanda M.; Nkambule, Bongani B.; Sadie-Van Gijsen, Hanel; Strijdom, Hans; Tiano, Luca; Dludla, Phiwayinkosi V. (MDPI, 2021-11-04)Excess epicardial adiposity, within a state of obesity and metabolic syndrome, is emerging as an important risk factor for the development of cardiovascular diseases (CVDs). Accordingly, increased epicardial fat thickness ...
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Willmer, Tarryn; Oosthuizen, Amberly; Dias, Stephanie; Mendham, Amy E.; Goedecke, Julia H.; Pheiffer, Carmen (Nature Research, 2022)We investigated gluteal (GSAT) and abdominal subcutaneous adipose tissue (ASAT) DNA methylation of FKBP5 in response to a 12-week intervention in African women with obesity, as well as the efect of the rs1360780 single ...
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Pheiffer, Carmen; Pillay-van Wyk, Victoria; Turawa, Eunice; Levitt, Naomi; Kengne, Andre P.; Bradshaw, Debbie (MDPI Publishing, 2021-05-30)Synthesis of existing prevalence data using rigorous systematic review methods is considered an effective strategy to generate representative and robust prevalence figures to inform health planning and policy. The purpose ...
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Nyawo, Thembeka A.; Dludla, Phiwayinkosi V.; Mazibuko-Mbeje, Sithandiwe E.; Mthembu, Sinenhlanhla X.H.; Nyambuya, Tawanda M.; Nkambule, Bongani B.; Sadie-Van Gijsen, Hanel; Strijdom, Hans; Pheiffer, Carmen (Springer, 2022-03)Emerging evidence suggests that epicardial fat thickness (EFT) may be a critical feature to understand cardiac health and determine the risk of heart failure. The current review critically assesses and discusses evidence ...
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Malaza, Nompumelelo; Masete, Matladi; Adam, Sumaiya; Dias, Stephanie; Nyawo, Thembeka; Pheiffer, Carmen (MDPI, 2022-08-31)Pregestational type 1 (T1DM) and type 2 (T2DM) diabetes mellitus and gestational diabetes mellitus (GDM) are associated with increased rates of adverse maternal and neonatal outcomes. Adverse outcomes are more common in ...
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Moetlediwa, Marakiya T.; Ramashia, Rudzani; Pheiffer, Carmen; Titinchi, Salam J. J.; Mazibuko-Mbeje, Sithandiwe E.; Jack, Babalwa U. (MDPI, 2023-09)Obesity is a major cause of morbidity and mortality globally, increasing the risk for chronic diseases. Thus, the need to identify more effective anti-obesity agents has spurred significant interest in the health-promoting ...
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Jackson, Hayley C.; Pheiffer, Carmen; Jack, Babalwa; Africander, Donita (Elsevier, 2023-09)The 3T3-L1 murine adipocyte cell line remains one of the most widely used models to study the mechanisms of obesity and related pathologies. Most studies investigate such mechanisms using mature adipocytes that have been ...
Now showing items 1-14 of 14