Browsing Health Sciences by UP Author "Peta, Kimberly"

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Effect of 2-methoxyestradiol treatment on early- and late-stage breast cancer progression in a mouse model

Peta, Kimberly; Durandt, Chrisna; Van Heerden, M.B. (Marlene); Joubert, Anna Margaretha; Pepper, Michael Sean; Ambele, Melvin Anyasi (Wiley, 2023-10)

The prevalence of breast cancer (BC) continues to increase and is the leading cause of cancer deaths in many countries. Numerous in vitro and in vivo studies have demonstrated that 2‐methoxyestradiol (2‐ME) has ...
SARS-CoV-2 variants, vaccines, and host immunity

Mistry, Priyal; Barmania, Fatima; Mellet, Juanita; Peta, Kimberly; Strydom, Adele; Viljoen, Ignatius M.; James, William; Gordon, Siamon; Pepper, Michael Sean (Frontiers Media SA, 2022-01-03)

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a new beta coronavirus that emerged at the end of 2019 in the Hubei province of China. SARS-CoV-2 causes coronavirus disease 2019 (COVID-19) and was declared ...
Similarities between tumour immune response and chronic wound microenvironment : influence of mesenchymal stromal/stem cells

Peta, Kimberly; Ambele, Melvin Anyasi; Pepper, Michael Sean (Hindawi, 2021-03-30)

Tumours are characterized by a state of chronic inflammation and are regarded as wounds that never heal. Mesenchymal stromal/stem cells (MSCs) are being considered as a possible treatment option. While MSCs can regulate ...

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