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Browsing Research Articles (Veterinary Tropical Diseases) by Author "Van den Biggelaar, Robin H.G.A."

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A detailed analysis of innate and adaptive immune responsiveness upon infection with Salmonella enterica serotype Enteritidis in young broiler chickens

Meijerink, Nathalie; Van den Biggelaar, Robin H.G.A.; Van Haarlem, Daphne A.; Stegeman, J. Arjan; Rutten, Victor P.M.G.; Jansen, Christine A. (BMC, 2021-08)

Salmonella enterica serotype Enteritidis (SE) is a zoonotic pathogen which causes foodborne diseases in humans as well as severe disease symptoms in young chickens. More insight in innate and adaptive immune responses ...
In vitro chicken bone marrow-derived dendritic cells comprise subsets at different states of maturation

Van den Biggelaar, Robin H.G.A.; Arkesteijn, Ger J.A.; Rutten, Victor P.M.G.; Van Eden, Willem; Jansen, Christine A. (Frontiers Media, 2020-02)

Research in chickens has been fundamental for the discovery of basic aspects of the immune system and has led to an interest in the in-depth characterization of avian immune cell types including dendritic cells (DCs). ...
Macrophage activation assays to evaluate the immunostimulatory capacity of avibacterium paragallinarum in a multivalent poultry vaccine

Van den Biggelaar, Robin H.G.A.; Van Eden, Willem; Rutten, Victor P.M.G.; Jansen, Christine A. (MDPI, 2020-11-10)

High-quality vaccines are crucial to prevent infectious disease outbreaks in the poultry industry. In vivo vaccination tests are routinely used to test poultry vaccines for their potency, i.e., their capacity to induce ...
Nitric oxide production and Fc receptor-mediated phagocytosis as functional readouts of macrophage activity upon stimulation with inactivated poultry vaccines in vitro

Van den Biggelaar, Robin H.G.A.; Van Eden, Willem; Rutten, Victor P.M.G.; Jansen, Christine A. (MDPI, 2020-06-22)

Vaccine batches must pass routine quality control to confirm that their ability to induce protection against disease is consistent with batches of proven efficacy from development studies. For poultry vaccines, these tests ...
Overcoming scientific barriers in the transition from in vivo to non-animal batch testing of human and veterinary vaccines

Van den Biggelaar, Robin H.G.A.; Hoefnagel, Marcel H.N.; Vandebriel, Rob J.; Sloots, Arjen; Hendriksen, Coenraad F.M.; Van Eden, Willem; Rutten, Victor P.M.G.; Jansen, Christine A. (Taylor and Francis Group, 2021-09-22)

INTRODUCTION : Before release, vaccine batches are assessed for quality to evaluate whether they meet the product specifications. Vaccine batch tests, in particular of inactivated and toxoid vaccines, still largely rely ...

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Browsing Research Articles (Veterinary Tropical Diseases) by Author "Van den Biggelaar, Robin H.G.A."

Browsing Research Articles (Veterinary Tropical Diseases) by Author "Van den Biggelaar, Robin H.G.A."

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