Le Manach, Claire; Paquet, Tanya; Brunschwig, Christel; Njoroge, Mathew; Han, Ze; Cabrera, Diego Gonzaalez; Bashyam, Sridevi; Dhinakaran, Rajkumar; Taylor, Dale; Reader, Janette; Botha, M.E. (Mariette); Churchyard, Alisje; Lauterbach, Sonja B.; Coetzer, Theresa L.; Birkholtz, Lyn-Marie; Meister, Stephan; Winzeler, Elizabeth A.; Waterson, David; Witty, Michael J.; Wittlin, Sergio; Jimenez-Diaz, Maria-Belen; Martinez, Maria Santos; Ferrer, Santiago; Angulo-Barturen, Inigo; Street, Leslie J.; Chibale, Kelly
(American Chemical Society, 2015-10-26)
Toward improving pharmacokinetics, in vivo
efficacy, and selectivity over hERG, structure−activity relationship
studies around the central core of antimalarial imidazopyridazines
were conducted. This study led to the ...
