Browsing by Supervisor "Bornman, Riana"

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Differential genome-wide DNA methylation in prostate tumours from South African men

Craddock, Jenna (University of Pretoria, 2021)

Background: DNA methylation is an epigenetic mechanism known to aid the progression of cancer, including prostate cancer. It is part of a cluster of molecular processes that initiate tumorigenesis and drive its early ...
Methylation of glutathione S-transferase pi 1 as an epigenetic biomarker for prostate cancer detection in black South African men

Channer, Kirsten Jade (University of Pretoria, 2021)

African ancestry is a major risk factor for prostate cancer (PCa), contributing to a 1.6-fold increased incidence and a 2.5-fold increased mortality in African Americans compared to European Americans. These are further ...

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