A biomimetic approach to the synthesis of a mycolic acid motif

dc.contributor.authorDriver, Kathy (Cathryn Helena Stanford)
dc.contributor.authorBalogun, Mohammed Olusegun
dc.contributor.authorToschi, Gianna
dc.contributor.authorVerschoor, Jan Adrianus
dc.contributor.authorBaird, Mark S.
dc.contributor.authorPilcher, Lynne A.
dc.contributor.emaillynne.pilcher@up.ac.zaen
dc.date.accessioned2010-01-28T10:13:31Z
dc.date.available2010-01-28T10:13:31Z
dc.date.issued2010-02
dc.description.abstractA new method for the stereoselective synthesis of the (R,R)-b-hydroxy-a-alkyl fatty acid fragment of mycolic acids, via an asymmetric anti-aldol reaction is reported. The ‘mycolic acid motif’ fragment was prepared in three steps and >98% ee.en
dc.identifier.citationDriver, C. H. S.; et al. A biomimetic approach to the synthesis of a mycolic motif, Tetrahedron Letters, vol. 51, no. 8, pp. 1185-1186 (2010), doi:10.1016/j.tetlet.2009.12.105en
dc.identifier.isbn0040-4039
dc.identifier.other10.1016/j.tetlet.2009.12.105
dc.identifier.urihttp://hdl.handle.net/2263/12794
dc.language.isoenen
dc.publisherElsevieren
dc.rightsElsevieren
dc.subjectMycolic acid motifen
dc.subjectAsymmetric anti-aldol reactionen
dc.subject.lcshTuberculosisen
dc.subject.lcshBiomimeticsen
dc.titleA biomimetic approach to the synthesis of a mycolic acid motifen
dc.typePostprint Articleen

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