The possible involvement of immunosuppression caused by a lentivirus in the aetiology of jaagsiekte and pasteurellosis in sheep

dc.contributor.authorMyer, M.S.
dc.contributor.authorHuchzermeyer, Hildegard F.A.K.
dc.contributor.authorYork, D.F
dc.contributor.authorHunter, P.
dc.contributor.authorGarnett, H.M.
dc.contributor.editorBigalke, R.D.
dc.contributor.upauthorVerwoerd, Daniel Wynand
dc.date.accessioned2014-10-14T10:56:03Z
dc.date.available2014-10-14T10:56:03Z
dc.date.created2014
dc.date.issued1988
dc.descriptionThe articles have been scanned in colour with a HP Scanjet 5590; 600dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format.en
dc.description.abstractA South African isolate of ovine lentivirus was shown to cause a mild immunosuppression in sheep, reflected by a reduced delayed hypersensitivity reaction. This effect, measured in terms of skin swelling after intradermal inoculation with tuberculin, showed a positive linear relationship with the latency period before the appearance of jaagsiekte symptoms in animals co-infected with JSRV, as well as with the activity of monocytes. In a parallel study, increased susceptibility of lentivirus-infected sheep to infection with Pasteurella haemolytica was demonstrated. It is concluded that the lentivirus may play an enhancing role in both viral and bacterial infections of sheep by compromising the host's cellular immune response.en
dc.description.librarianlmchunu2014en
dc.description.librarianmn2014
dc.identifier.citationMyer, MS, Huchzermeyer, HFAK, York, DF, Hunter, P, Verwoed, DW & Garnett, HM 1988, 'The possible involvement of immunosuppression caused by a lentivirus in the aetiology of jaagsiekte and pasteurellosis in sheep', Onderstepoort Journal of Veterinary Research, vol. 55, no. 3, pp. 127-133.en
dc.identifier.issn0330-2465
dc.identifier.urihttp://hdl.handle.net/2263/42373
dc.language.isoenen
dc.publisherPublished by the Government Printer, Pretoria.en
dc.rights©ARC - Onderstepoort and Faculty of Veterinary Science, University of Pretoria (original). ©University of Pretoria. Dept. of Library Services (digital).en
dc.subjectVeterinary medicineen
dc.subject.lcshVeterinary medicine -- South Africa
dc.titleThe possible involvement of immunosuppression caused by a lentivirus in the aetiology of jaagsiekte and pasteurellosis in sheepen
dc.typeArticleen

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