The presence of endotoxin activity in cases of experimentally-induced heartwater in sheep
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Date
Authors
Van Amstel, S.R.
Oberem, P.T.
Didomenico, M.
Kirkpatrick, R.D.
Mathee, J.
Journal Title
Journal ISSN
Volume Title
Publisher
Published by the Government Printer, Pretoria.
Abstract
The presence of endotoxin was examined in 5 sheep with experimentally-induced heartwater. Two peaks in endotoxin levels were recorded in 4 out of the 5 sheep during the acute stage of the disease. The 1st peak coincided with or occurred shortly after the febrile reaction (over 40 °C). The 2nd peak occurred 3-5 days after the 1st, and in 2 sheep this 2nd elevation in endotoxin levels was associated with severe clinical signs (rapid and laboured breathing, cyanosis and recumbency), and 1 of the 2 sheep died on the day of the 2nd elevation. Both endotoxin peaks were of short duration and levels had decreased in the 24-h follow-up samples.
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Keywords
Veterinary medicine
Sustainable Development Goals
Citation
Van Amstel, SR, Oberem, PT, Didomenico, M, Kirkpatrick, RD & Mathee, J 1988, 'The presence of endotoxin activity in cases of experimentally-induced heartwater in sheep', Onderstepoort Journal of Veterinary Research, vol. 55, no. 4, pp. 217-220.