Molecular detection of Yaba monkey tumour virus from a vervet monkey

dc.contributor.authorBrettschneider, Helene
dc.contributor.authorVoster, Johan H.
dc.contributor.authorLane, Emily P.
dc.contributor.authorVan Wilpe, Erna
dc.contributor.authorBiden, Peter
dc.contributor.authorDalton, Desire L.
dc.contributor.authorKotze, Antoinette
dc.date.accessioned2013-11-06T07:49:05Z
dc.date.available2013-11-06T07:49:05Z
dc.date.issued2013-09-20
dc.description.abstractYaba monkey tumour virus (YMTV) was first diagnosed in a colony of captive rhesus monkeys (Macaca mulatta) in Yaba, Nigeria. It has been implicated as the cause of cutaneous nodules in wild baboons (Papio species), rhesus monkeys (Macaca mulatta) and cynomolgus monkeys (Macaca fascicularis). This article reports a case of cutaneous pox lesions caused by YMTV in a free-ranging adult female vervet monkey (Chlorocebus pygerythrus) from the Umkomaas coastal area in South Africa. The virus was identified by molecular sequencing from fragments of the insulin metalloprotease-like protein and intracellular mature virion membrane protein as well as the DNA polymerase genes. Phylogenetic analyses of these gene regions revealed a 99% similarity of the sample to YMTV. Although human disease caused by YMTV is normally mild, it is recommended that persons in contact with non-human primates in the area of Umkomaas who develop cutaneous lesions should inform their doctors of the possibility of this infection. The extent and significance of the virus to human and non-human primates in South Africa are not known. To the authors’ knowledge, this is the first diagnosis of YMTV in South Africa and in vervet monkeys.en_US
dc.description.librarianam2013en_US
dc.description.sponsorshipThe South African National Research Foundation (NRF)en_US
dc.description.urihttp://www.jsava.co.zaen_US
dc.identifier.citationBrettschneider, H., Voster, J.H., Lane, E.P., Van Wilpe, E., Biden, P., Dalton, D.L. et al., 2013, 'Molecular detection of Yaba monkey tumour virus from a vervet monkey', Journal of the South African Veterinary Association 84(1), Art. #978, 5 pages. http://dx.DOI.org/ 10.4102/jsava.v84i1.978en_US
dc.identifier.issn0038-2809 (print)
dc.identifier.issn2224-9435 (online)
dc.identifier.other10.4102/jsava.v84i1.978
dc.identifier.urihttp://hdl.handle.net/2263/32285
dc.language.isoenen_US
dc.publisherOpenJournals Publishingen_US
dc.rights© 2013. The Authors. Licensee: AOSIS OpenJournals. This work is licensed under the Creative Commons Attribution License.en_US
dc.subjectVervet monkeys (Chlorocebus pygerythrus)en_US
dc.subjectYaba monkey tumour virus (YMTV)en_US
dc.subjectUmkomaas coastal area, South Africaen_US
dc.titleMolecular detection of Yaba monkey tumour virus from a vervet monkeyen_US
dc.typeArticleen_US

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