The serological and immunological relationship of type strains A and D of Pasteurella multocida to field isolates from sheep
Loading...
Date
Authors
Cameron, Colin McKenzie
Engelbrecht, Maria M.
Vermeulen, Aletta S.M.
Journal Title
Journal ISSN
Volume Title
Publisher
The Government Printer, Pretoria
Abstract
Investigations with antisera prepared in rabbits and sheep and active immunity experiments in mice showed that strains of Pasteurella multocida which, according to the haemagglutination test, are serologically related, do not necessarily give rise to cross immunity. Conversely, it was found that serologically unrelated strains may exhibit an appreciable degree of cross protection. The unreliability of the haemagglutination test as an indicator of immunological identity of strains was further confirmed in that peritoneal fluid from immunized mice showed passive protection properties despite the absence of haemagglutinating antibodies. There was no consistent agreement between the results obtained with antisera prepared in different species and active immunity experiments in mice, and this leads to the conclusion that different species probably vary quantitatively and qualitatively in their immune response to immunization with P. multocida. Attempts to determine whether combined bacterins afforded a better immunity than monovalent bacterins were inconclusive.
Description
The articles have been scanned in colour with a HP Scanjet 5590; 300dpi.
Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format.
Keywords
Veterinary Medicine
Sustainable Development Goals
Citation
Cameron, CM, Engelbrecht, MM & Vermeulen, ASM 1978, 'The serological and immunological relationship of type Strains A and D of Pasteurella multocida to field isolates from sheep’, Onderstepoort Journal of Veterinary Research, vol. 45, no. 4, pp. 215-220.