Assessing a sustainable manufacturing route to lapatinib

dc.contributor.authorStark, Roderick T.
dc.contributor.authorPye, Dominic R.
dc.contributor.authorChen, Wenyi
dc.contributor.authorNewton, Oliver J.
dc.contributor.authorDeadman, Benjamin J.
dc.contributor.authorMiller, Philip W.
dc.contributor.authorPanayides, Jenny-Lee
dc.contributor.authorRiley, Darren Lyall
dc.contributor.authorHellgardt, Klaus
dc.contributor.authorHii, King Kuok (Mimi)
dc.date.accessioned2023-10-16T07:37:26Z
dc.date.available2023-10-16T07:37:26Z
dc.date.issued2022-10
dc.description.abstractA synthetic route to an anti-cancer drug, lapatinib, was devised to support the development of a sustainable manufacturing process in South Africa. Quantitative metrics were employed to evaluate the sustainability of the key steps of the reaction.en_US
dc.description.departmentChemistryen_US
dc.description.librarianam2023en_US
dc.description.sponsorshipThe ROAR facility by EPSRC.en_US
dc.description.urihttps://pubs.rsc.org/en/journals/journalissues/reen_US
dc.identifier.citationStark, R.T., Pye, D.R., Chen, W. et al. 2022, 'Assessing a sustainable manufacturing route to lapatinib', Reaction Chemistry and Engineering, vol. 7, no. 11, pp. 2420-2426, doi : 10.1039/d2re00267a.en_US
dc.identifier.issn2058-9883 (online)
dc.identifier.other10.1039/d2re00267a
dc.identifier.urihttp://hdl.handle.net/2263/92873
dc.language.isoenen_US
dc.publisherRoyal Society of Chemistryen_US
dc.rights© The Royal Society of Chemistry 2022. This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.en_US
dc.subjectAnti-cancer drugen_US
dc.subjectLapatiniben_US
dc.subjectQuantitative metricsen_US
dc.subjectSDG-03: Good health and well-beingen_US
dc.subjectSouth Africa (SA)en_US
dc.titleAssessing a sustainable manufacturing route to lapatiniben_US
dc.typeArticleen_US

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