Assessing a sustainable manufacturing route to lapatinib
Loading...
Date
Authors
Stark, Roderick T.
Pye, Dominic R.
Chen, Wenyi
Newton, Oliver J.
Deadman, Benjamin J.
Miller, Philip W.
Panayides, Jenny-Lee
Riley, Darren Lyall
Hellgardt, Klaus
Hii, King Kuok (Mimi)
Journal Title
Journal ISSN
Volume Title
Publisher
Royal Society of Chemistry
Abstract
A synthetic route to an anti-cancer drug, lapatinib, was devised to support the development of a
sustainable manufacturing process in South Africa. Quantitative metrics were employed to evaluate the
sustainability of the key steps of the reaction.
Description
Keywords
Anti-cancer drug, Lapatinib, Quantitative metrics, SDG-03: Good health and well-being, South Africa (SA)
Sustainable Development Goals
Citation
Stark, R.T., Pye, D.R., Chen, W. et al. 2022, 'Assessing a sustainable manufacturing route to lapatinib', Reaction Chemistry and Engineering, vol. 7, no. 11, pp. 2420-2426, doi : 10.1039/d2re00267a.