The treatment of cholesterol : issues, effects and targets
| dc.contributor.author | Ker, James A. | |
| dc.contributor.email | james.ker@up.ac.za | en_US |
| dc.date.accessioned | 2011-04-05T10:07:41Z | |
| dc.date.available | 2011-04-05T10:07:41Z | |
| dc.date.issued | 2010-11 | |
| dc.description.abstract | Statins are the most powerful cholesterol lowering drugs currently available. Statins inhibit 3-hydroxy-3-methylglutaryl-coenzyme A (HMG CoA) reductase, which leads to reduced cholesterol synthesis. In addition, low-density cholesterol receptors on the hepatocyte surface are upregulated, leading to increased clearance of cholesterol. The end result is a significant reduction in cholesterol levels, and a consequent significant reduction in mortality and cardiovascular events in the appropriate individual. | en_US |
| dc.identifier.citation | Ker, JA 2010, 'The treatment of cholesterol : issues, effects and targets', South African Family Practice, vol. 52, no. 6, pp. 523-524. [http;//www.safpj.co.za] | en_US |
| dc.identifier.issn | 1726-426X (online) | |
| dc.identifier.issn | 1026-9177 (print) | |
| dc.identifier.uri | http://hdl.handle.net/2263/16212 | |
| dc.language.iso | en | en_US |
| dc.publisher | South African Academy of Family Practice/Primary Care | en_US |
| dc.rights | © SAAFP | en_US |
| dc.subject | Cholesterol | en_US |
| dc.subject | Hypercholesterolemia | en_US |
| dc.subject | Treatment | en_US |
| dc.subject | Drug therapy | en_US |
| dc.subject | Statins | en_US |
| dc.subject | Effectivity | en_US |
| dc.subject | LDL cholesterol | en_US |
| dc.subject | Target | en_US |
| dc.subject | Risk | en_US |
| dc.subject | Prevention | en_US |
| dc.subject | Elderly | en_US |
| dc.subject | Time factors | en_US |
| dc.subject | Atherosclerosis | en_US |
| dc.subject | Safety | en_US |
| dc.subject.lcsh | Cholesterol -- Treatment | |
| dc.title | The treatment of cholesterol : issues, effects and targets | en_US |
| dc.type | Article | en_US |